Food additives data book - wordpres

FOOD SAFETY ISSUES: Toxicology: LD 50 (oral, rat) = 2000 mg/kg
Toxic levels: For infants = 100,000 IU single dose; for children = 300,000 IU single dose; for adults =
500,000 IU single dose. Chronic toxicity can develop from prolonged daily intake of 25,000 IU
LEGISLATION: USA: CANADA:
GRAS in specified applications. For For specific regulations, refer to Part D: Vitamins, Minerals
adults and children over 4 years, and Amino Acids of the Food and Drug. Regulations, Health
Recommended Daily Intake is and Welfare Canada. For adults and children over 2 years,
5,000 IU Vitamin A Recommended Daily Intake is 1,000 RE Vitamin A. For
children under 2 years old, Recommended Daily Intake is 400
UK and EUROPE: RE Vitamin A
Recommended Daily Allowance is
800mg
REFERENCES: Ash, M., and Ash, I. (1995) Food Additives: Electronic Handbook. Gower Publishing Company,
Brookfield, VT, 05036, USA.
Augustin, J., and Scarbrough, F. E. (1990) Nutritional Additives. In: Branen, A. L., Davidson, P. M.,
and S. Salminen (Eds.), Food Additives, pp. 33–81.
Budavari, S. (1996) The Merck Index, 12th edition.
Health and Welfare Canada (1996) Part D: Vitamins, Minerals and Amino Acids. In: Food and Drug
Regulations. Department of Health, Ottawa, ON, Canada.
ANY OTHER RELEVANT INFORMATION: Nutritive activity measured in retinol equivalents (RE): 1 RE = 1mg retinol = 1.147mg retinyl acetate =
3.33 IU Vitamin A
Retinol 653