Zeitschrift für Rheumatologie – Supplement 1 - Deutsche ...

S4
Abstracts
FV1 Abstract Session I: Spondyloarthropathien/
Kristallarthritiden
FV1-1
Enthesitis in early Spondyloarthritis – results from a prospective longitudinal
observational study (GESPIC)
Rudwaleit M. 1 , Niewerth M. 0, Listing J. 0, Märker-Hermann E. 3 , Zeidler H. 2 ,
Braun J. 2 , Sieper J. 1
1 Reumatologie, Med. Klinik I, Charité - Campus Benjamin Franklin, Berlin,
2 3 Medizinische Hochschule, Hannover, Horst-Schmidt-Kliniken, Wiesbaden,
4 Rheumazentrum Ruhrgebiet, HernE
Background: Enthesitis is a clinical hallmark of spondyloarthritis. Th e
frequency and type of enthesitis in patients in early disease has not
been well studied.
Methods: Data were retrieved from the German Spondyloarthritis Inception
Cohort (GESPIC), a prospective longitudinal cohort on patients
with early SpA. Baseline data of 520 patients were analysed with
respect to current (baseline visit) and past enthesitis.
Results: Th e mean (SD) duration of symptoms was 5.4 (2.5) years
among 234 patients with AS, 2.7 (2.1) years in 196 patients with undifferentiated
spondyloarthritis (uSpA), 1.2 (2.0) years in 51 patients with
ReA, and 2.8 (2.0) years in 39 patients with psoriatic SpA (Pso-SpA).
Current enthesitis as assessed clinically was found in 25.9% of all patients,
and enthesitis ever was reported by 43.1% of all patients. When
comparing the various SpA subtypes, the highest frequency of current
enthesitis was found in ReA (32%), followed by uSpA (30.9%), Pso-SpA
(23.1%), and AS (20.5%). Similarly, enthesitis ever was found highest
in ReA (49%), followed by uSpA (47.7%), Pso-SpA (43.6%), and AS
(37.6%). Th e heal (insertion of achilles tendon and plantar fascia) was
a preferred enthesitic site of current enthesitis in both AS (16.9% of all
enthesitic region) and other SpA (27.4% of all enthesitic regions), with
an almost even distribution of other enthesitic sites. Enthesitis without
peripheral arthritis was found in 76 of all SpA patients 14.4%), and peripheral
arthritis without enthesitis in 88 of all SpA patients (16.7%).
Th e combination of enthesitis and concomitant peripheral arthritis occurred
in 59 patients (11.2%) which was more frequently than expected
(OR 2.7, 95% CI 1.8-4.0; p