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Abstracts (PDF file, 1.8MB) - Society for Risk Analysis

Abstracts (PDF file, 1.8MB) - Society for Risk Analysis

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SRA 2013 Annual Meeting <strong>Abstracts</strong><br />

M4-E.4 Prasad, B*; Sunger, N; Lennon, E; Drexel University;<br />

bp348@drexel.edu<br />

A risk model <strong>for</strong> inhaled toxins and spores associated<br />

with Stachybotrys chartarum<br />

Stachybotrys chartarum, a black mold frequently present in<br />

damp indoor environments, has been well-characterized due to<br />

its ability to produce human toxins such as trichothecene. The<br />

inhalation exposure to S. chartarum has been implicated in<br />

cases of acute idiopathic pulmonary hemorrhages (AIPH) in<br />

infants. The goals <strong>for</strong> this study were (1) to determine the risk<br />

of death in human infants using the maximum reported<br />

concentration of toxins and spores in an average<br />

water-damaged residential unit and (2) to determine the levels<br />

at which S. chartarum might pose as an acceptable risk.<br />

Studies of experimental administration of S. chartarum spores<br />

or trichothecene toxin on young animals were selected to model<br />

the dose response relationship between exposure and<br />

probability of death. The best-fit dose-response models <strong>for</strong> the<br />

threshold data were the Log-logistic <strong>for</strong> S. chartarum spores as<br />

exposure indicator in infant rats, and the Weibull <strong>for</strong> the<br />

trichothecene toxin in young mice. Stochastic risk estimates<br />

were developed using the proposed dose-response models to<br />

predict the risk of death in infants exposed to spores or toxins<br />

via inhalation. <strong>Analysis</strong> results showed that there is<br />

significantly high daily risk <strong>for</strong> acute 24-hour exposure to toxins<br />

ranging from 1 in 10,000 to 3 in a million. For a 10% daily risk<br />

based on inhalation instillation, the acceptable level of human<br />

equivalent dose in environmental samples was 413 spores/m3<br />

or 3.94E-05 mg-toxin/m3. Sensitivity analysis was conducted<br />

using Monte Carlo simulations to identify factors that are highly<br />

correlated with risk estimates. This study indicates that S.<br />

chartarum toxin exposure via inhalation in indoor environments<br />

may cause a risk <strong>for</strong> AIPH, but a conclusive epidemiology study<br />

is needed to validate the risk estimates. However, the<br />

conclusion of insignificant health risk to infants in moldy indoor<br />

environments is based on spore quantification and may<br />

under-report the disease burden associated with this fungi.<br />

W3-J.3 Price, JC*; Strellec, K; Industrial Economics, Inc.;<br />

Bureau of Ocean Energy Management; jprice@indecon.com<br />

The Development and Use of the Bureau of Ocean Energy<br />

Management’s Offshore Environmental Cost Model<br />

(OECM) to Evaluate the Environmental <strong>Risk</strong>s of Offshore<br />

Energy Development<br />

Under the Outer Continental Shelf (OCS) Lands Act, the Bureau<br />

of Ocean Energy Management (BOEM) is required to prepare<br />

<strong>for</strong>ward-looking five year schedules of proposed OCS lease<br />

sales that define the size, timing, and location of proposed oil<br />

and gas leasing activity. Policy decisions regarding the<br />

inclusion or exclusion of areas from these Five Year Programs<br />

require careful consideration of the environmental risks<br />

associated with exploration and development, as well as the<br />

risks that might be avoided when OCS development displaces<br />

production from other sources. BOEM requires the capacity to<br />

assess these risks in a timely manner, to allow <strong>for</strong> comparisons<br />

across multiple exploration and development scenarios and to<br />

in<strong>for</strong>m refinements to policy options under consideration. To<br />

address these competing needs, BOEM developed the Offshore<br />

Environmental Cost Model (OECM), an MS Access-based model<br />

that quantifies and (where possible) monetizes the net<br />

environmental and social impacts of each OCS exploration and<br />

development scenario. We present an overview of the model<br />

and illustrate how it is used to in<strong>for</strong>m development of BOEM’s<br />

Five Year Program.<br />

P.1 Qian, H*; Zaleski, R; Money, C; ExxonMobil Biomedical<br />

Sciences, Inc.; hua.qian@exxonmobil.com<br />

Approach <strong>for</strong> developing Specific Consumer Exposure<br />

Determinants (SCEDs) <strong>for</strong> fuel and lubricant scenarios<br />

The ECETOC TRA tool, a preferred lower tier exposure tool<br />

under REACH, provides conservative (intentionally high)<br />

estimates of consumer exposure. Under REACH, if a predicted<br />

exposure exceeds a substance hazard benchmark (Derived No<br />

Effect Level or DNEL) using lower tier tools, the assessment is<br />

either refined via higher tier analysis or <strong>Risk</strong> Management<br />

Measures are implemented to reduce the exposure predictions<br />

to values < DNEL. Much ef<strong>for</strong>t has recently been directed to<br />

identifying a rigorous and transparent approach <strong>for</strong> refining the<br />

TRA defaults so that initial exposure estimates are closer to<br />

reality, limiting the need to per<strong>for</strong>m higher tier analysis which<br />

requires more data. In 2012, ECETOC introduced the concept<br />

of Specific Consumer Exposure Determinants (SCEDs), a<br />

template that helps provide a basis <strong>for</strong> delivering a more<br />

realistic estimate of consumer exposure. We populated this<br />

template and developed 9 SCEDs to cover a range of consumer<br />

fuel use scenarios and 4 SCEDs to better define consumer<br />

lubricant use scenarios based on public data. SCED<br />

development required: data mining, data assessment, data<br />

documentation, and evaluation of the final scenario as whole.<br />

We describe the steps taken in SCED development, and provide<br />

examples of a completed product. This approach has general<br />

utility <strong>for</strong> documentation of consumer exposure determinants<br />

and development of improved consumer exposure scenarios. It<br />

is currently being implemented by other industry sectors as<br />

well.<br />

W3-F.1 Race, MS; SETI Institute; mracemom@aol.com<br />

<strong>Risk</strong> Communcation and In<strong>for</strong>mation Needs <strong>for</strong><br />

Anticipated Catastrophic Threats by NEOs<br />

Research on Near Earth Objects (NEO’s) has intensified in<br />

recent decades following the recognition that certain categories<br />

of objects have the potential to cause extensive or even global<br />

catastrophic impacts on life, environments, infrastructure, and<br />

perhaps even civilization as we know it. A small sector of the<br />

space science community has been systematically surveying<br />

and tracking asteroids in an attempt to detect potentially<br />

hazardous objects (PHOs) in advance, determine their<br />

probability of Earth impact, and subsequently send missions to<br />

deflect those that might be catastrophic. At a recent<br />

international meeting, deliberations after a conference-wide<br />

simulation exercise focused on the many scientific,<br />

technological, risk assessment, geopolitical, infrastructural and<br />

communication issues that will be involved in planning and<br />

developing an international Planetary Defense system. This<br />

presentation dissects the anticipated process <strong>for</strong> developing<br />

international planning and response preparedness <strong>for</strong> PHO<br />

threats and compares it with patterns pf familiar disaster cycles<br />

and threat levels Just as with preparedness and response to<br />

extreme threats(e.g., bioterrorism, WMDs, massive tsunamis or<br />

pandemics), there is need to incorporate fast-evolving science<br />

in<strong>for</strong>mation with new technologies and traditional disaster<br />

management infrastructures that involve coordination with<br />

officials and organizations at international, national,<br />

state/regional and local levels. In addition to addressing the<br />

risk communication needs of experts, there are also many<br />

unusual issues and in<strong>for</strong>mation needs of the diverse publics at<br />

risk. The operational and implementation challenges are<br />

unprecedented, and the associated risk communication and<br />

in<strong>for</strong>mation needs are likewise complex <strong>for</strong> both expert and<br />

public audiences. In addition to assessing the full spectrum of<br />

communication needs <strong>for</strong> potentially hazardous NEOs, the<br />

paper identifies a number of possible complications which will<br />

need special research and technological attention in the coming<br />

years.<br />

December 8-11, 2013 - Baltimore, MD

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