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Abstracts (PDF file, 1.8MB) - Society for Risk Analysis

Abstracts (PDF file, 1.8MB) - Society for Risk Analysis

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SRA 2013 Annual Meeting <strong>Abstracts</strong><br />

P.15 Willis, AM*; Maier, A; Reichard, J; Haber, L; Patterson, J;<br />

Toxicology Excellence <strong>for</strong> <strong>Risk</strong> Assessment (TERA);<br />

Willis@TERA.org<br />

Practice makes perfect: Lessons and outcomes based on<br />

mode of action/human relevance framework application<br />

to case studies.<br />

A public workshop, organized by a Steering Committee of<br />

scientists from government, industry, university, and research<br />

organizations, was held at the National Institute of<br />

Environmental Health Sciences (NIEHS) in September, 2010.<br />

The workshop explored the development of dose-response<br />

approaches <strong>for</strong> receptor-mediated liver cancer within a Mode of<br />

Action (MOA) Human Relevance Framework (HRF)<br />

(WHO/IPCS). Case studies addressed activation of the aryl<br />

hydrocarbon receptor (AHR), the constitutive androstane<br />

receptor (CAR), and the pregnane X receptor alpha<br />

(PPAR&#945;). The workshop case studies provided a valuable<br />

exercise in applying the MOA/HRF and a number of insights<br />

and lessons emerged that may be useful <strong>for</strong> future applications.<br />

Inclusion of associative events and modulating factors into the<br />

framework was useful <strong>for</strong> the consideration of mechanistic data<br />

to in<strong>for</strong>m dose-response. In particular, associative events and<br />

modulating factors could be a useful approach <strong>for</strong> the<br />

integration of molecular and biomarker data to in<strong>for</strong>m risk<br />

assessment. Further guidance in the MOA/HRF would be useful<br />

to clarify the number of key events needed to define a MOA, to<br />

address the absence of human studies needed to in<strong>for</strong>m critical<br />

interspecies differences, and to assess activation of multiple<br />

MOA cascades and interactive molecular signaling pathways. In<br />

addition, variation in human population susceptibility needs to<br />

be addressed <strong>for</strong> assessing human relevance, particularly the<br />

possibility that populations exhibit widely ranging individual<br />

thresholds. A qualitative “value of in<strong>for</strong>mation” approach to<br />

assess the utility of further research to better in<strong>for</strong>m<br />

dose-response and a detailed and systematic uncertainty<br />

analysis <strong>for</strong> use in the framework would be useful.<br />

M4-G.3 WIlson, RS*; McCaffrey, S; The Ohio State University,<br />

USDA Forest Service; wilson.1376@osu.edu<br />

Do I stay or do I go? <strong>Risk</strong> attitudes and evacuation<br />

decisions during a wildfire event<br />

Most socio-psychological wildfire research focuses on risk<br />

mitigation actions taken be<strong>for</strong>e a fire event occurs with less<br />

attention paid to homeowner actions during a fire. However,<br />

increasing incidences of homeowners refusing to evacuate or<br />

leaving at the last minute during wildfires and other natural<br />

disasters had led to a growing interest in research into<br />

evacuation decision making. We randomly selected<br />

homeowners from three counties in the states of Washington,<br />

Texas and South Carolina, and conducted a mailed survey to<br />

assess their evacuation decision making process in the spring of<br />

2013. These three counties were specifically chosen because of<br />

their high wildfire risk, but they each varied in terms of past<br />

experience with wildfire and mandatory evacuation orders.<br />

Drawing on Protection Motivation Theory and the Extended<br />

Parallel Process Model, we assessed individual homeowner's<br />

threat and coping appraisal related to wildfire, as well as<br />

individual risk attitudes. We expected that individuals with risk<br />

averse attitudes would have higher threat appraisals and lower<br />

coping appraisals than those with risk tolerant attitudes. As a<br />

result it was expected that risk averse individuals would be<br />

more likely to evacuate early, whereas the risk tolerant would<br />

vary in their evacuation response based on their respective<br />

appraisals. In effect, the pattern would be that evacuation<br />

decisions are made heuristically, whereas decisions to stay and<br />

defend, or wait and see, are more systematic and driven by<br />

individual differences in the perceived threat and ability to cope<br />

with wildfire. To ensure maximum public safety, crisis<br />

communication ef<strong>for</strong>ts could target the risk tolerant, focusing<br />

on correcting the misperceptions or critical beliefs that tend to<br />

drive individuals to ignore evacuation orders and place their<br />

lives in danger.<br />

T3-G.1 Wilson, RS; The Ohio State University;<br />

wilson.1376@osu.edu<br />

In<strong>for</strong>mation processing, risk and uncertainty: A<br />

roundtable discussion<br />

There is a breadth of research that in<strong>for</strong>ms our understanding<br />

of how individuals process in<strong>for</strong>mation about risk and<br />

uncertainty, with much of this research focusing on the<br />

heuristic processing of in<strong>for</strong>mation through a variety of<br />

mechanisms. As a result of decades of research, many useful<br />

theoretical models have evolved to in<strong>for</strong>m how this type of<br />

processing influences judgments (e.g., hazard acceptance<br />

models, the risk in<strong>for</strong>mation seeking and processing model,<br />

etc). Ideally, these theoretical perspectives should influence the<br />

way we as practitioners communicate and structure decisions,<br />

yet the breadth of perspectives can make it difficult to know<br />

which is "best" or "right" <strong>for</strong> a particular context. This<br />

roundtable brings together an interdisciplinary panel of<br />

accomplished risk and decision scientists who will discuss how<br />

their research in<strong>for</strong>ms our understanding of in<strong>for</strong>mation<br />

processing and what their findings suggest <strong>for</strong> improving risk<br />

communication and decision making in the context of real-world<br />

problems. Each panelist will have an opportunity to address<br />

these two key points be<strong>for</strong>e opening up the session to general<br />

discussion and questions from the audience. Invited roundtable<br />

panelists include: Paul Slovic (Decision Research) Joe Arvai<br />

(University of Calgary) Katherine McComas (Cornell University)<br />

Michael Siegrist (ETH Zurich) Janet Yang (State University of<br />

New York at Buffalo) Nathan Dieckmann (Oregon Health and<br />

Science University)<br />

W4-F.2 Wilson, GS; Global Catastrophic <strong>Risk</strong> Institute;<br />

grant@gcrinstitute.org<br />

Minimizing Global Catastrophic and Existential <strong>Risk</strong>s<br />

from Emerging Technologies Through International Law<br />

Mankind is rapidly developing “emerging technologies” in the<br />

fields of bioengineering, nanotechnology, and artificial<br />

intelligence that have the potential to solve humanity’s biggest<br />

problems, such as by curing all disease, extending human life,<br />

or mitigating massive environmental problems like climate<br />

change. However, if these emerging technologies are misused<br />

or have an unintended negative effect, the consequences could<br />

be enormous, potentially resulting in serious, global damage to<br />

humans (known as “global catastrophic harm”) or severe,<br />

permanent damage to the Earth—including, possibly, human<br />

extinction (known as “existential harm”). The chances of a<br />

global catastrophic risk or existential risk actually materializing<br />

are relatively low, but mankind should be careful when a losing<br />

gamble means massive human death and irreversible harm to<br />

our planet. While international law has become an important<br />

source of global regulation <strong>for</strong> other global risks like climate<br />

change and biodiversity loss, emerging technologies do not fall<br />

neatly within existing international regimes, and thus any<br />

country is more or less free to develop these potentially<br />

dangerous technologies without practical safeguards that<br />

would curtail the risk of a catastrophic event. In light of these<br />

problems, this presentation serves to discuss the risks<br />

associated with bioengineering, nanotechnology, and artificial<br />

intelligence; review the potential of existing international law to<br />

regulate these emerging technologies; and propose an<br />

international regulatory regime that would put the international<br />

world in charge of ensuring that low-probability, high-risk<br />

catastrophes never materialize.<br />

December 8-11, 2013 - Baltimore, MD

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