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Section 6. Health Hazard Data,continuedMedkal Conditions Aggravated by Long-Term Rxposum: Nervous. liver. kidney. or skin disorders. Target Organs: Liver. kidney, eyes.upper respiratory tract. skin, <strong>and</strong> central nervous system. primary Entry Routes: Inhalation snd skin <strong>and</strong> eye contsct. Acute Effects: Exposure tohigh levels can cause liver damage which may take several weeks to develop. Vapor exposum can cause slight smarting of the eyes <strong>and</strong> thmat (inm~ high concentrations). In human studies, exposum to 2000 ppm/5 min caused mild CNS depression: 600 ppm/lO min caused numbness around thelouth, dizziness, <strong>and</strong> incoordination; 180 ppfl hr caused mild eye. nose, <strong>and</strong> throat irritation. flushing of the face <strong>and</strong> neck, headache, somnoma,<strong>and</strong> slurred speech. Skin contact may produce dermatitis because of perchlomethylene’s defatting action (more common after repeatedexposure). Direct eye contact causes tearing <strong>and</strong> burning but no permanent damage. Ingestion is mm but can cause irritation of the lips, mouth adgastrointestinal tract irregular heartbeat nausea I% vomiting diarrhea (possibly blood stained), drowsiness. unconsciousness, <strong>and</strong> rifk of puhonaryedema (fluid in lungs). Chronic Effects: Prolonged exposure can cause impaired memory, extremity (h<strong>and</strong>s, feet) weakness, peripheralneumpathies, impaired vision, muscle cramps, liver damage (fatty degeneration, necrosis, yellow jaundice, <strong>and</strong> dark urine) <strong>and</strong> kidney damage(oliguric uremia, amjesfion <strong>and</strong> granular swelling).FIRST AID Rescuers must not enter areas with potentiaUy high peddoroethykne kvek without a se&contained breathing apparatus.Eyes: Do not allow victim to tub or keep eyes tightly shut. Gently lift eyelids <strong>and</strong> flush immediately <strong>and</strong> continuously with flooding amounts ofwater until transported to an emergency medical facility. Consult a physician immediately. Skin: Quicwy remove contaminated clothing. Rinsewith flooding amounts of water <strong>for</strong> at least 15 min. Wash exposed area with soap <strong>and</strong> water. For reddened or blistered skin, consult a physician.Inhaiation: Remove exposed petson to Besh air <strong>and</strong> suppott breathing as needed Never adminirtcr u&nalinr Ingestion: Never give anything bymouth to an unconscious or convulsing person. Contact a poison control center <strong>and</strong> unless otherwise advised, have that cons&ru uad ufen persondrink 1 to 2 glasses of water. then induce vomiting. Be sure victims head is positioned to avoid aspiration of vomitus into the lungs. Note toPhysicians: Monitor level of consciousness, EEG (abnormalaties may indicate chronic toxicity), blood enyme levels (<strong>for</strong> 2 to 3 wk after exposure),EKG, adequacy of respirations & oxygenation. <strong>and</strong> liver <strong>and</strong> kidney function. BEZs: C$& io expired air (10 ppm). sample prior to last shiftof <strong>work</strong> week; C+& in blood (1 mg/L). sample prior to last shift of <strong>work</strong> week; trichlomacetic acid in urine (7 mg/L). sample at end of <strong>work</strong>week.Section 7. Spill, Leak, <strong>and</strong> Disposal Procedures :Spill/Leak: Notify safety personnel, isolate <strong>and</strong> ventilate area. deny enlay. <strong>and</strong> stay upwind. Shut off ignition sources (although noncombustible, it<strong>for</strong>ms toxic vapors from thermal decomposition). For small spills. take up with earth, s<strong>and</strong>, vermiculite, or other absorbent, noncombustiblematerial <strong>and</strong> place in suitable containers <strong>for</strong> later disposal. For large spills, dike far ahead of spill <strong>and</strong> await reclamation or disposal. Report anyrelease in excess of 1 lb. Follow applicable OSHA regulations (29 CFR 1910.120). Environmental Transport: If released to <strong>soil</strong>, perchloroethyleneevaporates <strong>and</strong> some leaches to groundwater. It may absorb slightly to <strong>soil</strong>s with heavy organic matter. Biodegradation may be important inanaerobic <strong>soil</strong>s. In water, it is subjecto rapid volatilization with an estimated half-life from

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