110 RS Rob<strong>in</strong>son, AJ Hammond, DC Wathes, MG Hunter and GE MannConclusionsThe establishment of pregnancy <strong>in</strong> cattle <strong>in</strong>volves aseries of highly coord<strong>in</strong>ated <strong>in</strong>teractions between theovary, endometrium and embryo. First, the appropriatetim<strong>in</strong>g of these <strong>in</strong>teractions is critical. In particular, thetim<strong>in</strong>g of the post-ovulatory rise <strong>in</strong> progesterone determ<strong>in</strong>esboth the transport of the embryo and thestimulation of appropriate endometrial secretions requiredfor the rapid development of the embryo. Any<strong>in</strong>adequacy <strong>in</strong> the post-ovulatory progesterone leads todelayed embryo development and embryo mortality.The ‘status’ of the pre-ovulatory follicle and rate ofsubsequent luteal development have profound effects onluteal function. Secondly, the precise <strong>in</strong>terplay betweenthe embryo and the endometrium on which it isdependent are also crucial. The embryo must blockluteolysis to establish pregnancy. It does this <strong>in</strong> the cowby secret<strong>in</strong>g IFNT, which <strong>in</strong> turn directly suppresses theup-regulation of the OXTR <strong>in</strong> the lum<strong>in</strong>al epithelium.Embryonic development is <strong>in</strong>fluenced by a number ofendometrial growth factors, such as the IGFs. Thesefactors are likely mediators of the cow’s metabolic statusand are thus excit<strong>in</strong>g targets for development ofstrategies to alleviate the decl<strong>in</strong><strong>in</strong>g fertility.AcknowledgementsThis work has been funded by M<strong>in</strong>istry of Agriculture, Fisheries andFood, DEFRA, BBSRC, the Wellcome Trust and the Milk DevelopmentCouncil. 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278 FF Bartol, AA Wiley and CA Bagn
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Reprod Dom Anim 43 (Suppl. 2), 280-
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282 KC Caires, JA Schmidt, AP Olive
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284 KC Caires, JA Schmidt, AP Olive
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286 KC Caires, JA Schmidt, AP Olive
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Reprod Dom Anim 43 (Suppl. 2), 288-
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290 I Dobrinskisuccessful also betw
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292 I DobrinskiCreemers LB, Meng X,
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294 I DobrinskiOkutsu T, Suzuki K,
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296 N Rawlings, ACO Evans, RK Chand
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298 N Rawlings, ACO Evans, RK Chand
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300 N Rawlings, ACO Evans, RK Chand
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304 A Dinnyes, XC Tian and X Yanggr
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306 A Dinnyes, XC Tian and X YangIn
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308 A Dinnyes, XC Tian and X YangHo
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Reprod Dom Anim 43 (Suppl. 2), 310-
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312 RC Bott, DT Clopton and AS Cupp
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314 RC Bott, DT Clopton and AS Cupp
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316 RC Bott, DT Clopton and AS Cupp
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318 BK Whitlock, JA Daniel, RR Wilb
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320 BK Whitlock, JA Daniel, RR Wilb
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322 BK Whitlock, JA Daniel, RR Wilb
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Reprod Dom Anim 43 (Suppl. 2), 324-
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326 CR Barb, GJ Hausman and CA Lent
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328 CR Barb, GJ Hausman and CA Lent
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330 CR Barb, GJ Hausman and CA Lent
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332 C Galli, I Lagutina, R Duchi, S
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334 C Galli, I Lagutina, R Duchi, S
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336 C Galli, I Lagutina, R Duchi, S
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340 D Rath and LA JohnsonCommercial
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342 D Rath and LA JohnsonThe Commer
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344 D Rath and LA JohnsonX- and Y-b
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346 D Rath and LA JohnsonWalker SK,
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348 JM Vazquez, J Roca, MA Gil, C C
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350 JM Vazquez, J Roca, MA Gil, C C
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352 JM Vazquez, J Roca, MA Gil, C C
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354 JM Vazquez, J Roca, MA Gil, C C
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356 CBA Whitelaw, SG Lillico and T
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358 CBA Whitelaw, SG Lillico and T
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360 ACO Evans, N Forde, GM O’Gorm
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362 ACO Evans, N Forde, GM O’Gorm
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364 ACO Evans, N Forde, GM O’Gorm
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366 ACO Evans, N Forde, GM O’Gorm
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Reprod Dom Anim 43 (Suppl. 2), 368-
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370 JP Kastelic and JC Thundathilsp
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372 JP Kastelic and JC Thundathilme
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Reprod Dom Anim 43 (Suppl. 2), 374-
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376 GC AlthouseTable 1. Potential s
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378 GC Althousesemen to the domesti
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380 B Leboeuf, JA Delgadillo, E Man
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382 B Leboeuf, JA Delgadillo, E Man
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384 B Leboeuf, JA Delgadillo, E Man
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Reprod Dom Anim 43 (Suppl. 2), 386-
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388 N Kostereva and M-C HofmannFig.
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390 N Kostereva and M-C HofmannMMPs
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392 N Kostereva and M-C HofmannTado
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394 P Mermillod, R Dalbie` s-Tran,
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396 P Mermillod, R Dalbie` s-Tran,
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398 P Mermillod, R Dalbie` s-Tran,
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400 P Mermillod, R Dalbie` s-Tran,
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402 K Kikuchi, N Kashiwazaki, T Nag
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404 K Kikuchi, N Kashiwazaki, T Nag
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406 K Kikuchi, N Kashiwazaki, T Nag
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408 B ObackNumber of publications20
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410 B ObackReprogramming Ability of
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412 B Obackstudies have shown that
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414 B ObackFig. 4. Climbing mount e
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416 B ObackRenard JP, Maruotti J, J
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418 P Loi, K Matzukawa, G Ptak, Y N
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420 P Loi, K Matzukawa, G Ptak, Y N
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422 P Loi, K Matzukawa, G Ptak, Y N
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Table of Contents Volume 43 · Supp