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Reproduction in Domestic Animals

Reproduction in Domestic Animals

Reproduction in Domestic Animals

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Reproductive Status Assessed by Milk Progesterone 1174 ng ⁄ ml (31 of 59 of false negatives). Of these, <strong>in</strong> 24cases smoothed progesterone did not decrease below6ng⁄ ml. This high-progesterone oestrus <strong>in</strong>creas<strong>in</strong>glyseems to be a real biological phenomenon (Fig. 2). Ofthe rema<strong>in</strong><strong>in</strong>g 28 false negatives, enlarg<strong>in</strong>g the w<strong>in</strong>dow()3 to + 5 dfo) around oestrus for align<strong>in</strong>g modeldetected and ratified oestruses by ±3 days of the oestruscaptured 21 cases. Accept<strong>in</strong>g these 21 cases as a matchreduced the number of false negatives to 38 result<strong>in</strong>g <strong>in</strong> amodel sensitivity of 93.3%. This sensitivity comparedvery favourably with the sensitivities reported for othermethods of oestrus detection (Firk et al. 2002), evenwhen these methods are used <strong>in</strong> very favourablecircumstances such as high <strong>in</strong>tensity visual oestrusdetection (85.7% Van Eerdenburg 2006) or after oestrussynchronisation (91.3% for tail pa<strong>in</strong>t, 81.4% forpedometers Cavalieri et al. 2003). Only the comb<strong>in</strong>edactivity, milk yield, milk temperature and conductivitymodel of de Mol et al. (1999) had a sensitivity (94%)that matched that for the ratified oestruses. Althoughthis sensitivity was less than the 99% found us<strong>in</strong>g theconfirmed oestruses.In addition to enlarg<strong>in</strong>g the number of oestrusesaccepted as ‘true’, the profile match<strong>in</strong>g procedure allowsexam<strong>in</strong>ation of those cases <strong>in</strong> which the model <strong>in</strong>dicatedoestrus <strong>in</strong> the absence of a ratified oestrus, and thusallows calculation of model specificity. There were 171model-detected oestruses (exclud<strong>in</strong>g first <strong>in</strong>creases <strong>in</strong>progesterone >4 ng ⁄ ml) that did not match a ratifiedoestrus (i.e. false positives). Thus, the model had apositive predictive value (proportion of model detectedoestruses that are true oestruses) of 72.2%[445 ⁄ (445 + 171)]. The total number of progesteronemeasures <strong>in</strong> the period of oestrus cycl<strong>in</strong>g (Status = 1and profile match<strong>in</strong>g weight

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