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1238A AASLD ABSTRACTS HEPATOLOGY, October, 2015<br />

person for WD was 1,643.15 USD. Conclusion: The prevalence<br />

of WD was slightly lower in Korean than other countries,<br />

showing an increase from 2009. Since about one third of WD<br />

patients had advanced liver disease such as cirrhosis and cancer,<br />

more efforts for early diagnosis and treatment for WD are<br />

warranted, especially during pediatric age.<br />

Disclosures:<br />

The following authors have nothing to disclose: Joo Yeong Baeg, Eun Sun Jang,<br />

Mo-ran Ki, Bo Hyun Kim, Kyung-ah Kim, Hwa Young Choi, Sook-Hyang Jeong<br />

2114<br />

Relapse of porphyria cutanea tarda after achieving<br />

remission: A Meta-analysis<br />

Maira Rizwan 1 , Karl Anderson 2 , Ashwani K. Singal 1 ; 1 Gastroenterology<br />

and Hepatology, University of Alabama, Birmingham, AL;<br />

2 university of texas, Galveston, TX<br />

Background: Porphyria cutanea tarda (PCT) is due to inhibition<br />

of hepatic uroporphyrinogen decarboxylase (UROD).<br />

Phlebotomy and 4-aminoquinolines (hydroxychloroquine and<br />

chloroquine, preferably low-dose) are effective treatment<br />

options. Data comparing relapse after documenting biochemical<br />

remission of PCT with these treatments are lacking. Methods:<br />

Pubmed and Embase databases were searched for <strong>studies</strong><br />

reporting data on PCT relapse with minimum follow up for<br />

1 year after achieving remission with either phlebotomy or<br />

4-aminoquinolines. End point of treatment with phlebotomy<br />

was ferritin

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