studies

838A AASLD ABSTRACTS HEPATOLOGY, October, 2015
1273
Morbid Obesity and Diabetes (DM) are Associated with
Increased Risk of Death on the Liver Transplant (LT)
Waiting List
Ani A. Kardashian 1 , Jennifer L. Dodge 2 , John P. Roberts 2 , Danielle
Brandman 1 ; 1 Medicine, University of California, San Francisco,
San Francisco, CA; 2 Surgery, University of California, San Francisco,
San Francisco, CA
Purpose: Obesity is a growing problem in LT candidates, paralleling
the US obesity epidemic and the increase in LT for
nonalcoholic steatohepatitis (NASH). While post-LT survival
appears to be similar in obese and non-obese patients, data
is scarce regarding risk of waitlist dropout in morbidly obese
patients. We aimed to determine the impact of obesity on
waitlist outcomes and evaluate predictors of dropout in those
with morbid obesity or NASH. Methods: We retrospectively
evaluated LT candidates listed between 3/02-12/13. We
performed a competing risk analysis to evaluate predictors of
removal or death on the waitlist. Variables with p-value40. Compared to those
with BMI 25-29.9, patients with BMI≥40 were more likely to
be female (46% vs 28%), diabetic (25% vs 18%), have NASH
(35% vs 13%), and have shorter median waitlist times (161 vs
208 days); all p