studies

HEPATOLOGY, VOLUME 62, NUMBER 1 (SUPPL) AASLD ABSTRACTS 837A
MS was diagnosed at 3, 6 and 12 months post-LT respectively
in 6/26 (23%), 7/23 (30%) e 7/16 (44%) patients. After 12
months post-LT 11/16 patients (66%) had an HOMA2 test
suggestive for IR, whereas at 6 months post-LT that finding
was present in 10/23 (43%). No cardiovascular events were
recorded in the study cohort. In conclusion, these data show
that post-LT MS affects nearly half of LT recipients, starting early
after LT. Lifestyle modifications, should be recommended to
transplanted recipients, starting in the early post-LT period. This
would facilitate prevention of body weight gain and the associated
abnormalities, thus reducing incidence of post-LT MS and
the related cardio-vascular events.
Disclosures:
The following authors have nothing to disclose: Veronica Pepe, Giacomo Germani,
Alberto Ferrarese, Alberto Zanetto, Elena Nadal, Ilaria Bortoluzzi, Francesco
P. Russo, Marco Senzolo, Umberto Cillo, Patrizia Burra
Intraoperative Factors
1271
How intra-operative factors affect kidney recovery after
simultaneous liver-kidney transplantation (SLK)
Mario Spaggiari 1 , Mohamed Shaaban 2 , Galal El-Gazzaz 1 , Lisa
Louwers 1 , Emmanouil Palaios 1 , Cristiano Quintini 1 , Federico N.
Aucejo 1 , Koji Hashimoto 1 , Teresa Diago 1 , Masato Fujiki 1 , Bijan
Eghtesad 1 , Charles M. Miller 1 , Mauricio Perilla 2 , Dympna Kelly 1 ;
1 Cleveland Clinic, Cleveland, OH; 2 Department of Anesthesia,
Cleveland Clinic Foundation, Cleveland, OH
Introduction: The present study by analyzing our SLK population
wants to identify the modifiable risk factors that affect
kidney recovery after transplant with particular focus on the
intraoperative events. Material and Methods: This a retrospective
analysis performed between 2004 and 2014. The
patient/graft survival of SLK were compared with the group of
liver transplant alone (OLT) and kidney transplant alone (KT)
in the same era. DGF was defined as the need of dialysis in
the first week post-transplant. Results: 64 SLK were performed
from 2004 to 2014.21.8% of patients (14/64) didn’t require
dialysis at the time of the transplant. When compared to OLT
(n=936) and KT (n=632) there was no significant differences
in patient and graft survival. The incidence of DGF was higher
in the SLK group (27%) compared to 20% in the KT (P= 0.3).
Pre-operative factors associated with DGF were higher recipient
BMI (p