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HEPATOLOGY, VOLUME 62, NUMBER 1 (SUPPL) AASLD ABSTRACTS 473A<br />

26% to 19%. Paracentesis and thoracentesis increased, 12%<br />

to 20%. Conclusion: Elderly subjects with CLD present with<br />

more comorbidities, more complicated liver disease, higher<br />

prevalence of NAFLD rather than viral hepatitis, higher procedure<br />

utilization and substantial inpatient mortality. The epidemiology<br />

of CLD in the elderly is changing and warrants chronic<br />

disease management models to mitigate the burden expected<br />

to be borne by Medicare.<br />

Disclosures:<br />

The following authors have nothing to disclose: Michael Hagan, Maria A. Kouznetsova,<br />

Sumeet K. Asrani<br />

529<br />

Communication, sequence and system modeling of GI/<br />

Hepatology outpatient and inpatient work flows for targeting<br />

clinical decision support tools<br />

Anne Miller 3,4 , Jejo D. Koola 3,4 , Michael E. Matheny 3,4 , Julie<br />

Ducom 1 , Jason M. Slagle 4 , Erik J. Groessl 1,5 , Sterling M. Dubin 1,2 ,<br />

Freneka F. Minter 3,4 , Jennifer H. Garvin 6,7 , Matthew B. Weinger 4 ,<br />

Samuel B. Ho 1,5 ; 1 VA San Diego Healthcare System, San Diego,<br />

CA; 2 Medicine, University of California, San Diego, San Diego,<br />

CA; 3 VA Tennessee Valley Healthcare System, Nashville, TN;<br />

4 Vanderbilt University, Nashville, TN; 5 University of California,<br />

San Diego, San Diego, CA; 6 VA Salt Lake City Healthcare System,<br />

Salt Lake City, UT; 7 University of Utah, Salt Lake City, UT<br />

Objectives: Increasing numbers of cirrhotic patients have high<br />

re-admission and mortality rates. Interventions that improve<br />

care coordination with well-targeted clinical decision support<br />

(CDS) can improve outcomes. We analyzed work processes<br />

in outpatient and inpatient settings to identify opportunities for<br />

CDS placement. Methods: Ethnographic observations, guided<br />

by user-centered design principles, occurred at two VA medical<br />

centers. Within 24 hours, pairs of experienced observers met<br />

to interpret their notes. The debriefings elucidated the structure<br />

and meaning of work as practiced resulting in: 1) Affinity diagrams<br />

to aggregate interpreted themes, insights & intervention<br />

design ideas; 2) Communication models to elucidate information<br />

flows across roles; 3) Sequence models to define work<br />

in goal-oriented terms, and 4) Artifact analyses to elucidate<br />

cognitive & problem solving structures. Results: At Site A, 26<br />

physicians, 3 nurses and 1 clerk were observed in: 1) gastrointestinal<br />

(GI) outpatient clinics (31%); 2) inpatient medical<br />

rounds (69%). At Site B, 14 physicians were observed in: 1)<br />

GI outpatient (14%) & Primary Care clinics (29%); 2) Emergency<br />

Department (21%); 3) inpatient medical rounds (29%)<br />

and 4) inpatient GI consult rounds (7%). 2/3 of participants<br />

were trainees & 1/3 were attending physicians. We categorized<br />

168 and 147 notes, respectively, during debriefings<br />

into 3 major themes each with several sub-themes. Team and<br />

Care Coordination addressed work allocation among local<br />

and distributed providers. Alerting and Reviewing addressed<br />

information access and retrieval so as to confer meaning to<br />

patients’ situations. Executing patients’ plans-of-care addressed<br />

the implementation of clinical goals & tasks. We identified<br />

resident physicians as the primary vertical and horizontal communication<br />

and coordination hubs. Using artifact analyses we<br />

found that residents’ paper patient printouts most effectively<br />

supported their clinical work. Using sequence analysis we identified<br />

patient assessment & planning as critical resident tasks<br />

to be targeted for CDS interventions (e.g., automated dashboards,<br />

data visualization, diagnostic and therapeutic checklists).<br />

Conclusions: The success of quality improvement depends<br />

on how well interventions are integrated into routine work.<br />

This study identified 4 intervention design goals to enhance<br />

cirrhosis care: 1) interventions should assume distributed work<br />

environs; 2) target residents; 3) integrate CDS with clinical<br />

assessment & planning processes rather than global point of<br />

order entry; and 4) be provided in both electronic & hardcopy<br />

forms. The design/integration of specific CDS tools is ongoing.<br />

Disclosures:<br />

Samuel B. Ho - Grant/Research Support: Genentech, Gilead; Speaking and<br />

Teaching: Prime Education, Inc<br />

The following authors have nothing to disclose: Anne Miller, Jejo D. Koola,<br />

Michael E. Matheny, Julie Ducom, Jason M. Slagle, Erik J. Groessl, Sterling M.<br />

Dubin, Freneka F. Minter, Jennifer H. Garvin, Matthew B. Weinger<br />

530<br />

Reduction of 30 day Readmission Rate in Patients with<br />

End Stage Liver Disease<br />

Simona Rossi 1 , Manisha Verma 1 , Catherine Reynolds 2 , Dee Morrison<br />

2 , June Smith 2 , Cindy Mcglone 1 , Eyob L. Feyssa 1 , Victor J.<br />

Navarro 1 ; 1 Medicine, Albert Einstein Medical Center Philadelphia,<br />

Philadelphia, PA; 2 Nursing, Albert Einstein Medical Center Philadelphia,<br />

Philadelphia, PA<br />

BACKGROUND: Patients with end stage liver disease (ESLD) are<br />

a unique population prone to high hospital readmission rates,<br />

as evidenced by a 37% thirty day readmission rate (Volk M,<br />

2012) compared to a 20% readmission rate in the Medicare<br />

population of patients excluding those with liver disease. AIM:<br />

We tested an intervention designed specifically for patients with<br />

ESLD, intended to reduce 30 day readmission rates. METHODS:<br />

Using tools described in the evidence based literature for non-<br />

ELSD as a starting point, a liver specific discharge process was<br />

developed comprising 1) patient and family centered nurse<br />

administered medication training for adherence and side effect<br />

monitoring accompanied by performance feedback to assure<br />

understanding, 2) salt and free water restriction counseling,<br />

and 3) 48 hour post-discharge scripted telephone interviews<br />

for symptom and medication side effect monitoring, and follow<br />

up adherence. This process was implemented in June 2014.<br />

Nurses were educated to perform these interventions. Positive<br />

findings (e.g.; new symptoms) reported during the phone interview<br />

were managed with pre-determined responses, including<br />

electronic alerts to a physician for immediate intervention.<br />

Mean paired differences were compared for 30 day readmission<br />

rates during the six month period prior to implementation<br />

of the process, following a standard discharge process, and for<br />

the six months after implementation of the new discharge process.<br />

As this was a quality improvement exercise, all patients<br />

admitted to the Inpatient Liver Unit of the Einstein Medical Center,<br />

Philadelphia, were included. Results: The mean (SD) 30<br />

day hospital readmission rate for the six month period prior<br />

to implementation was 30.18(6.76), compared with 21.83<br />

(8.3) following implementation (p=0.19). Conclusion: In the<br />

ESLD population, strategies to reduce hospital readmissions

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