studies

1122A AASLD ABSTRACTS HEPATOLOGY, October, 2015
sensitivity index (ISI).Patients with HCV infection had significantly
lower TC and TG than healthy controls. This difference
remained significant when adjusted for sex, age and BMI.
During the antiviral treatment, we found a significant reduction
of TC levels independently from the outcome of treatment,
but this rebounded to baseline in patients achieving a SVR
(4.51-4.45mmol/l, P=0.509) and stayed below baseline in
patients without SVR (4.39-4.72mmol/l, P=0.004). Serum TG
levels were also significantly elevated in both groups at the end
of treatment, and persisted until week 24 post-treatment only
in the patients with SVR. In sustained responders, fasting insulin
(P=0.007), C-peptide (P