studies

HEPATOLOGY, VOLUME 62, NUMBER 1 (SUPPL) AASLD ABSTRACTS 605A
William M. Rosenberg - Advisory Committees or Review Panels: Janssen, Merk,
Gilead, Merk, Gilead, GSK; Board Membership: iQur Limited, iQur Limited;
Consulting: siemens; Speaking and Teaching: siemens, Roche
The following authors have nothing to disclose: Brian J. Hogan, James O’Beirne,
David W. Patch, Dominic Yu, Ioanna Parisi, Andrew R. Hall, Ankur Srivastava,
Paul M. Trembling, Sudeep Tanwar
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Association of skin capsular distance with accuracy
of liver stiffness measurements of the FibroScan XL
probe—comparison with virtual touch quantification
and the FibroScan M probe
Erina Kumagai 1,3 , Keiko Korenaga 2 , Masaaki Korenaga 1,2 ,
Misuzu Ueyama 1,3 , Yoshihiko Aoki 2 , Yoko Yamagiwa 1 , Masatoshi
Imamura 2 , Kazumoto Murata 1,2 , Tatsuya Kanto 1,2 , Naohiko
Masaki 1,2 , Sumio Watanabe 3 , Masashi Mizokami 1,2 ; 1 The
Research Center for Hepatitis and Immunology, National Center
for Global Health and Medicine at Kohnodai, Ichikawa, Japan;
2 Department of Gastroenterology and Hepatology, Kohnodai Hospital,
National Center for Global Health and Medicine, Ichikawa,
Japan; 3 Department of Gastroenterology, Juntendo University
School of Medicine, Bunkyo-ku, Japan
Background and Aim: The FibroScan XL probe was specifically
designed for obese patients. However, there is no data
regarding its use in Japanese individuals, who tend to be less
obese than Caucasians. This study evaluates the diagnostic
performance of the XL probe, the FibroScan M probe, and the
virtual touch quantification (VTQ) method in Japanese patients
with chronic liver disease. Methods: A total of 664 consecutive
patients with chronic liver disease who underwent ultrasonography
were prospectively enrolled from June through October
2014. The cause of liver disease was hepatitis C virus (HCV,
n = 179), hepatitis B virus (HBV, n = 79), fatty liver (n = 264),
or non-HBV non-HCV hepatitis (n = 142). Liver stiffness was
measured by VTQ, the M probe, and the XL probe on the same
day. Liver stiffness measurement (LSM) failure was defined as
zero valid shots; unreliable examination was defined as