studies

576A AASLD ABSTRACTS HEPATOLOGY, October, 2015
735
Obesity is associated with increased mortality and need
for transplant in patients with alcoholic liver disease
Mohamed G. Shoreibah 2 , Donny Kakati 1 , Sudha Kodali 2 , Ashwani
K. Singal 2 ; 1 Internal Medicine, University of Alabama at Birmingham,
Birrmingham, AL; 2 Gastroenetrology and Hepatology,
University of Alabam at Birmingham, Birmingham, AL
Obesity is associated with increased mortality and need for
liver transplant in patients with alcoholic liver disease Background
and aims: Alcoholic liver disease (ALD) is the second
most common cause of cirrhosis and the need for liver transplant.
Increasing prevalence of obesity has also resulted in a
growing population of obese alcoholics. Data on the impact of
obesity on the natural history of ALD are scarce. Methods: We
performed a retrospective study on 286 well characterized ALD
patients. After excluding 28 patients without body mass index
(BMI) data at presentation, 258 ALD patients were stratified
into three groups based on BMI as Group A: normal weight
(BMI40 g/d in women and >60
g/d in men for >5 years. Results: Group A (N=97; mean age
47) differed compared to overweight alcoholics (N=78; mean
age 46 y) and obese alcoholics (N=83; mean age 43 y) for
male gender (53% vs. 58% vs. 70%; P