studies

828A AASLD ABSTRACTS HEPATOLOGY, October, 2015
Comparing centers performing transplants for alcoholic hepatitis
to centers not performing such transplants
LT: Liver transplantation; AH: Alcoholic hepatitis; NRS: Non-response
to steroids
Disclosures:
Brendan M. McGuire - Grant/Research Support: bayer healthcare, salix
The following authors have nothing to disclose: Mohsen Hasanin, Derek Dubay,
Thomas D. Schiano, Ashwani Singal
1251
15 first-days over-immunosuppression (IS) is NOT associated
with immune-outcome measures post-liver transplantation
(LT)
Tommaso Di Maira, Victoria Aguilera, Angel Rubin, Carmen
Vinaixa, Maria Garcia, Salvador Benlloch, Eva Montalva, Angel
Moya, Fernando San Juan, Rafae Lopez-Andujar, Martin Prieto,
Marina Berenguer; La Fe University Hospital, Valencia, Spain
Body: Background & Aims: A recent study has described a
strong association between early post liver transplantation (LT)
(IS) and outcome. We aimed to confirm these findings in a
cohort with long-term follow up. Methods: Tac and CsA trough
levels obtained during the first 15 postLT days of patients
transplanted between 2006-2008 were collected. High IS
was defined by median Tac or CsA higher than 10 ng/ml or
250 ng/ml respectively and/or the presence of a peak of Tac
or CsA greater than 20 ng/ml and 400 ng/ml, respectively.
Optimal IS was defined by median Tac or CsA levels between
7-10 ng/ml or 150-250 ng/ml. Exclusion criteria were: lack of
available data,