studies

HEPATOLOGY, VOLUME 62, NUMBER 1 (SUPPL) AASLD ABSTRACTS 631A
Disclosures:
The following authors have nothing to disclose: Daniela Ladner, Kathryn Skibba,
Kathryn Jackson, Niloufar Safaeinili, David S. Goldberg, Lisa B. VanWagner,
Satyender Goel, Abel Kho, Amna Daud, Nazanin Salehitezangi, Anton I. Skaro
850
Objective Measurement of Karnofsky Performance Status
in End Stage Liver Disease Patients
Lisa Louwers, Emmanouil Palaios, Galal El-Gazzaz, Mario Spaggiari,
Bijan Eghtesad, Dympna Kelly; Transplantation and Hepatobiliary
Surgery, Cleveland Clinic, Cleveland, OH
Purpose In OLT the Karnofsky performance score (KPS) is a
heavily weighted component in risk stratification in the Scientific
Registry of Transplant Recipients (SRTR), but there are no
guidelines as to its use in patients with ESLD. Our goal was to
develop an objective designation of the KPS in ESLD patients.
Methods We developed and implemented an algorithm to
objectively assign KPS to OLT patients, used at the time of OLT
offer (see figure). We reviewed KPS in our patients before and
after the tool was implemented. Group 1: 2004 – 2009, 788
patients, 69% male, mean age 53±13 yrs. Group 2: 2011-
2014, 468 patients, 68% male, mean age 53±16 yrs. Group
2 patients had a higher mean chemical MELD score (18±8 vs
20±11, p=0.001), were more often hospitalized at the time
of transplant (17.5% vs 23.1%, p=0.024), had a higher incidence
of COPD and tobacco use (2.6% vs 8.8% and 44.7%
vs 54.5% respectively, p