studies

HEPATOLOGY, VOLUME 62, NUMBER 1 (SUPPL) AASLD ABSTRACTS 913A
1441
Comparing the liver stiffness by transient elastography
in cirrhosis patients with PBC and HBV to predict the
risk of esophageal variceal bleeding
Ying Huang 1 , Haiyun Zhang 1 , Li Xiao 1 , Liqing Zhu 1 , Qingjing
Zhu 2 , Xiaohua Hou 1 , Ling Yang 1 ; 1 Division of Gastroenterology,Department
of Internal Medicine, Huazhong University of Science&Technology,
Wuhan, China; 2 Wuhan Medical Treatment
Center, Wuhan, China
Background&Aim: Staging hepatic fibrosis is critical for the
evaluation and deternination of prognosis in chronic liver diseases.
Variceal bleeding is the servere complications of liver
cirrhosis. Endosocopy as the only means to evaluate the varices
and risk of bleeding is not an easy examination to be
accepted by patients with expensive price and poor tolerance.
Transient elastography (TE) is useful as non-invasive diagnositic
method for predicting liver stiffness and portal hypertension.
Our aim was to analyze the diagnostic accuracy of liver stiffness
measurement(LSM) and the esophageal variceal grading
and the risk of esophageal variceal bleeding in different etiological
cirrhosis patients with HBV infection or primary billiary
cirrhosis by transient elastography. Patients and Methods:
Endoscopy and transient elastography were performed in 24
primary biliary cirrhosis patients and 66 hepatitis B related
cirrhosis. The relationships of the liver stiffness between esophageal
variceal degree and the risk of esophageal variceal
bleeding, as well as the hematological and biochemical laboratory
parameters were analyzed. Results: The grade of
esophageal varices is highly correlated with the stiffness of
the liver(P