ProVitalDNA - Package - DEMO EN

INFLAMMATION
Inflammatory responses and risk of injury
During excessive exercise, the tissue is slightly damaged in many places. The immune
system normally recognizes this as a normal process and there is no inflammation or
swelling. The immune system only reacts to serious damage and a swelling of the ankle,
for example, occurs.
Certain genes control the aggressiveness of the immune system. So, in some cases, light sportrelated
tissue damage can lead to an excessively aggressive inflammation, which doesn’t
trigger any apparent swelling but causes excessive tissue damage. Therefore, tendon injuries
(usually the Achilles tendon or the tendons in the knee) can occur over a longer period of time.
Genetic traits
SYMBOL rs NCBI POLYMORPH GENOTYPE
IL1RN rs419598 C>T C/T
IL6 rs1800795 G>C G/C
TNFa rs1800629 G>A G/G
GDF5 rs143383 G>A G/A
COL5A1 rs12722 T>C C/C
IL-6R rs2228145 A>C A/A
Col1A1 rs1800012 G>T T/T
CRP rs3093066 A>C C/C
Legend: rsNCBI = database number of genetic variation, Polymorphism = type of genetic change, Genotype =
the genetic laboratory result
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