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ProVitalDNA - Package - DEMO EN

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Statement 5<br />

Genes influence how our body reacts to a specific weight loss program, and can increase the results up to<br />

2.5-fold.<br />

A study by (Lindi et al., Diabetes 51: 2581-2586, 2002) concluded that people who followed a 3-year program of moderate<br />

exercise and dieting, and had the optimal genetic profile, lost 2.5 times more weight than those with an unfavorable<br />

genetic profile (8.3 kg on the average in comparison to 3.4 kg on average). However, 1 year after completion of the study,<br />

the weight of people with the favorable genetic profile had increased significantly more than the weight of the group<br />

with the unfavorable profile. Thus, the favorable profile makes sports and diet more effective, but also makes the yo-yo<br />

effect more severe.<br />

Publications<br />

➤ http://www.ncbi.nlm.nih.gov/pubmed/?term=12145174 Diabetes. 2002 Aug;51(8):2581-6. Association of the Pro12Ala<br />

polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish<br />

Diabetes Prevention Study. Lindi VI, Uusitupa MI, Lindström J, Louheranta A, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka<br />

P, Keinänen-Kiukaanniemi S, Laakso M, Tuomilehto J; Finnish Diabetes Prevention Study.<br />

Your genes do not change and the traits and variations will remain the same from your birth until the end of your life.<br />

Therefore, you do not need to retest your genes as you will always get the same results. Genetic analyses are technically<br />

very complex and there is a small chance that a genetic variant may have been missed. To prevent this, we have<br />

integrated several quality assurance measures in our processes which ensure the accuracy of our diagnosis. We do<br />

everything possible to ensure that the results of your analysis are accurate.<br />

However, you should be aware that there is the (unlikely) possibility that still unidentified genes have an effect on<br />

weight loss and were thus missed by this analysis. Therefore keep track of our new products and product improvements<br />

in order to stay informed about newly discovered relevant genes.<br />

<strong>DEMO</strong>_ML Page 241 of 295

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