European Patent Bulletin 2012/36 - European Patent Office
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European Patent Bulletin 2012/36 - European Patent Office

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(C07D) I.1(1)<br />

(71) MSD Oss B.V., Kloosterstraat 6, 5349 AB<br />

Oss, NL<br />

(72) COOKE, Andrew John, Newhouse Central<br />

Scotland ML1 5SH, GB<br />

CARSWELL, Emma Louise, Newhouse<br />

Central Scotland ML1 5SH, GB<br />

BENNETT, David, Jonathan, Newhouse<br />

Central Scotland ML1 5SH, GB<br />

(74) Hussain, Deeba, et al, Merck & Co., Inc.<br />

<strong>Patent</strong> Department Hertford Road,<br />

Hoddesdon Hertfordshire EN11 9BU, GB<br />

C07D 211/42 → (51) A61P 11/06<br />

C07D 211/46 → (51) A61P 11/06<br />

C07D 211/56 → (51) C07D 205/04<br />

C07D 213/56 → (51) A61P 11/06<br />

C07D 213/61 → (51) A61P 11/06<br />

(51) C07D 213/74 (11) 2 493 856 A1*<br />

C07D 239/34 C07D 239/42<br />

C07D 401/06 C07D 405/12<br />

C07D 413/06 C07D 493/08<br />

A61K 31/44 A61K 31/4427<br />

A61K 31/505 A61K 31/506<br />

(25) En (26) En<br />

(21) 10773287.7 (22) 25.10.2010<br />

(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR<br />

GB GR HR HU IE IS IT LI LT LU LV MC MK<br />

MT NL NO PL PT RO RS SE SI SK SM TR<br />

(86) EP 2010/066016 25.10.2010<br />

(87) WO 2011/051201 2011/18 05.05.2011<br />

(30) 27.10.2009 EP 091741<strong>36</strong><br />

(54) POSITIVE ALLOSTERISCHE MODULATO-<br />

REN (PAM)<br />

POSITIVE ALLOSTERIC MODULATORS<br />

(PAM)<br />

MODULATEURS ALLOSTÉRIQUES POSI-<br />

TIFS (MAP)<br />

(71) F.Hoffmann-La Roche AG, Grenzacherstrasse<br />

124, 4070 Basel, CH<br />

(72) GREEN, Luke, CH-4057 Basel, CH<br />

GUBA, Wolfgang, 79379 Muellheim, DE<br />

JAESCHKE, Georg, CH-4059 Basel, CH<br />

JOLIDON, Synese, CH-4223 Blauen, CH<br />

LINDEMANN, Lothar, CH-4056 Basel, CH<br />

RICCI, Antonio, CH-2540 Grenchen, CH<br />

RUEHER, Daniel, F-68480 Raedersdorf, FR<br />

STADLER, Heinz, CH-4053 Basel, CH<br />

VIEIRA, Eric, CH-4402 Frenkendorf, CH<br />

(74) Poppe, Regina, F.Hoffmann-La Roche AG<br />

<strong>Patent</strong> Department Grenzacherstrasse 124,<br />

4070 Basel, CH<br />

C07D 213/75 → (51) C07D 211/28<br />

C07D 213/803 → (51) C25B 3/04<br />

C07D 217/12 → (51) A61P 11/06<br />

(51) C07D 219/10 (11) 2 493 857 A1*<br />

C07D 403/12 A61K 31/4375<br />

A61P 35/00 A61K 31/506<br />

(25) En (26) En<br />

(21) 10784876.4 (22) 01.11.2010<br />

(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR<br />

GB GR HR HU IE IS IT LI LT LU LV MC MK<br />

MT NL NO PL PT RO RS SE SI SK SM TR<br />

(86) IL 2010/000905 01.11.2010<br />

(87) WO 2011/051950 2011/18 05.05.2011<br />

(30) 01.11.2009 US 256992 P<br />

02.09.2010 US 379502 P<br />

(54) 9-AMINOACRIDINDERIVATE, IHRE HER-<br />

STELLUNG UND VERWENDUNG<br />

9-AMINOACRIDINE DERIVATIVES, THEIR<br />

PREPARATION AND USES<br />

Europäisches <strong>Patent</strong>blatt<br />

<strong>European</strong> <strong>Patent</strong> <strong>Bulletin</strong><br />

<strong>Bulletin</strong> européen des brevets<br />

DÉRIVÉS DE 9-AMINOACRIDINE, LEUR<br />

PRÉPARATION ET LEURS UTILISATIONS<br />

(71) Ariel-University Research and Development<br />

Company Ltd., Hiryat HaMada, 44837 Ariel,<br />

IL<br />

(72) GELLERMAN, Gary, 754<strong>36</strong> Rishon Lezion, IL<br />

(74) Kalhammer, Georg, et al, Lederer & Keller<br />

<strong>Patent</strong>anwälte Unsöldstrasse 2, 80538 München,<br />

DE<br />

C07D 231/12 → (51) A61P 11/06<br />

(51) C07D 231/14 (11) 2 493 858 A1*<br />

C07D 401/12 C07D 403/12<br />

C07D 405/12 C07D 413/12<br />

C07D 417/12 A61P 35/00<br />

A61K 31/42 A61K 31/438<br />

A61K 31/497 A61K 31/4523<br />

A61K 31/5377 A61K 31/416<br />

A61K 31/44<br />

(25) En (26) En<br />

(21) 10781918.7 (22) 27.10.2010<br />

(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR<br />

GB GR HR HU IE IS IT LI LT LU LV MC MK<br />

MT NL NO PL PT RO RS SE SI SK SM TR<br />

BA ME<br />

(86) FI 2010/000065 27.10.2010<br />

(87) WO 2011/051540 2011/18 05.05.2011<br />

(30) 27.10.2009 US 255159 P<br />

(54) ANDROGEN-REZEPTOR-MODULIERENDE<br />

VERBINDUNGEN<br />

ANDROGEN RECEPTOR MODULATING<br />

COMPOUNDS<br />

COMPOSÉS MODULATEURS DE RÉCEP-<br />

TEURS DES ANDROGÈNES<br />

(71) Orion Corporation, Orionintie 1, 02200<br />

Espoo, FI<br />

(72) WOHLFAHRT, Gerd, FIN-00210 Helsinki, FI<br />

TÖRMÄKANGAS, Olli, FIN-20380 Turku, FI<br />

SALO, Harri, FIN-20300 Turku, FI<br />

HÖGLUND, Iisa, FIN-20300 Turku, FI<br />

KARJALAINEN, Arja, FI-02210 Espoo, FI<br />

KNUUTTILA, Pia, FIN-20660 Littoinen, FI<br />

HOLM, Patrik, FIN-21630 Lielahti TL, FI<br />

RASKU, Sirpa, FI-01520 Vantaa, FI<br />

VESALAINEN, Anniina, FIN-20540 Turku, FI<br />

(74) Sexton, Jane Helen, et al, J A Kemp 14<br />

South Square Gray's Inn, London WC1R<br />

5JJ, GB<br />

(51) C07D 231/38 (11) 2 493 859 A1*<br />

A61K 31/415 A61P 25/28<br />

(25) En (26) En<br />

(21) 10704496.8 (22) 26.01.2010<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK SM TR<br />

(86) EP 2010/000437 26.01.2010<br />

(87) WO 2011/050864 2011/18 05.05.2011<br />

(30) 26.10.2009 PCT/EP2009/007627<br />

(54) NEUE VERBINDUNGEN ZUR BEHAND-<br />

LUNG VON ERKRANKUNGEN IM ZUSAM-<br />

MENHANG MIT PROTEINMISSFALTUNG<br />

NEW COMPOUNDS FOR THE<br />

TREATMENT OF DISEASES RELATED TO<br />

PROTEIN MISFOLDING<br />

NOUVEAUX COMPOSÉS POUR LE TRAI-<br />

TEMENT DE MALADIES LIÉES À UN<br />

MAUVAIS REPLIEMENT DE PROTÉINES<br />

(71) Universität Duisburg-Essen, Universitatsstrasse<br />

2, 45141 Essen, DE<br />

(72) SCHRADER, Thomas, 40822 Mettmann, DE<br />

HOCHDÖRFFER, Katrin, 67240 Wabenheim-<br />

Roxheim, DE<br />

MARZ-BERBERICH, Julia, 45143 Essen, DE<br />

NAGEL-STEGER, Luitgard, 40764 Langenfeld,<br />

DE<br />

BITAN, Gal, Los Angeles CA 90095-7334, US<br />

95<br />

Anmeldungen<br />

Applications<br />

Demandes (<strong>36</strong>/<strong>2012</strong>) 05.09.<strong>2012</strong><br />

SINHA, Sharmistha, Los Angeles CA 90024-<br />

4842, US<br />

(74) Strehlke, Ingo Kurt, <strong>Patent</strong>anwälte Gesthuysen,<br />

von Rohr & Eggert Huyssenallee 100,<br />

45128 Essen, DE<br />

(51) C07D 231/44 (11) 2 493 860 A1*<br />

(25) En (26) En<br />

(21) 1077<strong>36</strong>15.9 (22) 26.10.2010<br />

(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR<br />

GB GR HR HU IE IS IT LI LT LU LV MC MK<br />

MT NL NO PL PT RO RS SE SI SK SM TR<br />

(86) EP 2010/066162 26.10.2010<br />

(87) WO 2011/051284 2011/18 05.05.2011<br />

(30) 30.10.2009 EP 09174558<br />

(54) VERFAHREN ZUR HERSTELLUNG VON 4-<br />

SULFINYL-PYRAZOL-DERIVATEN<br />

PROCESS FOR THE PREPARATION OF 4-<br />

SULFINYL-PYRAZOLE DERIVATIVES<br />

PROCÉDÉ DE PRÉPARATION DE DÉRIVÉS<br />

DE 4-SULFINYL-PYRAZOLE<br />

(71) BASF SE, 67056 Ludwigshafen, DE<br />

(72) KORTE, Alexander, Guaratingueta-SP CEP:<br />

12516-280, BR<br />

HORNUNG, Paul, 67308 Rüssingen, DE<br />

C07D 233/61 → (51) A61P 11/06<br />

(51) C07D 233/64 (11) 2 493 861 A1*<br />

A61K 31/4164<br />

(25) En (26) En<br />

(21) 10773495.6 (22) 25.10.2010<br />

(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR<br />

GB GR HR HU IE IS IT LI LT LU LV MC MK<br />

MT NL NO PL PT RO RS SE SI SK SM TR<br />

(86) US 2010/053923 25.10.2010<br />

(87) WO 2011/053546 2011/18 05.05.2011<br />

(30) 26.10.2009 US 254960 P<br />

(54) VERFAHREN FÜR DIE ZUBEREITUNG VON<br />

1-(4-((1R,2S,3R)-1,2,3,4-TETRAHY-<br />

DROXYBUTYL)-1H-IMIDAZOL-2-<br />

YL)ETHANON<br />

METHODS OF PREPARING 1-(4-<br />

((1R,2S,3R)-1,2,3,4-TETRAHYDROX-<br />

YBUTYL)-1H-IMIDAZOL-2-YL)ETHANONE<br />

PROCÉDÉS DE PRÉPARATION DE 1-(4-<br />

((1R,2S,3R)-1,2,3,4-TÉTRAHYDROXY-<br />

BUTYL)-1H-IMIDAZOL-2-YL)ÉTHANONE<br />

(71) Lexicon Pharmaceuticals, Inc., 8800 Technology<br />

Forest Place, The Woodlands, TX<br />

77381, US<br />

(72) WU, Wenxue, Princeton Junction, New<br />

Jersey 08550, US<br />

(74) Hewson, Timothy John, et al, Abel & Imray<br />

20 Red Lion Street, London, WC1R 4PQ, GB<br />

(51) C07D 233/64 (11) 2 493 862 A1*<br />

C07D 401/12 C07D 403/12<br />

C07D 407/12 C07D 409/12<br />

C07D 413/12 C07D 417/12<br />

A61K 31/4164 A61K 31/4178<br />

A61P 35/00 A61P 37/00<br />

A61P 31/00<br />

(25) En (26) En<br />

(21) 10779<strong>36</strong>4.8 (22) 27.10.2010<br />

(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR<br />

GB GR HR HU IE IS IT LI LT LU LV MC MK<br />

MT NL NO PL PT RO RS SE SI SK SM TR<br />

BA ME<br />

(86) US 2010/054289 27.10.2010<br />

(87) WO 2011/056652 2011/19 12.05.2011<br />

(30) 28.10.2009 US 255762 P<br />

(54) IMIDAZOLDERIVATE ALS IDO-HEMMER<br />

IMIDAZOLE DERIVATIVES AS IDO INHI-<br />

BITORS<br />

DÉRIVÉS IMIDAZOLE COMME INHIBI-<br />

TEURS DE L'IDO<br />

(71) Newlink Genetics Corporation, 2901 South<br />

Loop Drive, Suite 3900, Ames, IA 50010, US

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