European Patent Bulletin 2012/36 - European Patent Office

(C07D) I.1(1)
ENGLER, Amanda, C., Cambridge MA
02139, US
LEE, Hyung-il, Somerville MA 02145, US
(74) Trueman, Lucy Petra, Barker Brettell LLP
100 Hagley Road, Edgbaston Birmingham
B16 8QQ, GB
C07D 277/30 → (51) A61P 11/06
C07D 277/46 → (51) C07C 235/34
C07D 295/096 → (51) C07D 211/28
C07D 295/12 → (51) C07C 235/34
C07D 295/135 → (51) C07D 211/28
C07D 295/192 → (51) C07D 211/28
C07D 305/06 → (51) C07C 233/55
(51) C07D 307/58 (11) 2 493 869 A1*
C07D 311/76 C07D 493/04
C09B 57/00 G01N 33/58
G01N 33/68
(25) En (26) En
(21) 10768259.3 (22) 25.10.2010
(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR
GB GR HR HU IE IS IT LI LT LU LV MC MK
MT NL NO PL PT RO RS SE SI SK SM TR
(86) EP 2010/066064 25.10.2010
(87) WO 2011/051225 2011/18 05.05.2011
(30) 26.10.2009 FR 0957495
(54) VERFAHREN ZUR SYNTHESE VON EPI-
COCCONON-ANALOGA
PROCESS FOR SYNTHESIZING EPICOC-
CONONE ANALOGS
PROCÉDÉ POUR SYNTHÉTISER DES
ANALOGUES D'ÉPICOCCONONE
(71) Universite de Rouen, 1, rue Thomas Becket,
76130 Mont-Saint-Aignan, FR
Centre National de la Recherche Scientifique
CNRS, 3 rue Michel Ange, 75016 Paris 16,
FR
Institut National Des Sciences Appliquees De
Rouen, Avenue de l'Université, 76801 Saint-
Etienne du Rouvray, FR
MacQuarie University, Balaclava Road North
Ryde, Sydney, New South Wales 2109, AU
(72) FRANCK, Xavier, F-76230 Bois Guillaume,
FR
PEIXOTO, Philippe, F-76100 Rouen, FR
KARUSO, Peter, Helmuth, Killara New South
Wales 2109, AU
(74) Cabinet Plasseraud, 52, rue de la Victoire,
75440 Paris Cedex 09, FR
C07D 311/04 → (51) A61P 11/06
(51) C07D 311/22 (11) 2 493 870 A1*
A61K 31/5377 A61K 31/558
(25) En (26) En
(21) 10769052.1 (22) 25.10.2010
(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR
GB GR HR HU IE IS IT LI LT LU LV MC MK
MT NL NO PL PT RO RS SE SI SK SM TR
BA ME
(86) GB 2010/051788 25.10.2010
(87) WO 2011/051704 2011/18 05.05.2011
(30) 27.10.2009 EP 09306017
(54) CHROMENONDERIVATE MIT ANTITU-
MORWIRKUNG
CHROMENONE DERIVATIVES WITH ANTI-
TUMOUR ACTIVITY
DÉRIVÉS DE CHROMÉNONE À ACTIVITÉ
ANTITUMORALE
(71) AstraZeneca AB, 151 85 Södertälje, SE
(72) BARLAAM, Bernard, Christophe, F-51689
Reims Cedex 2, FR
Europäisches Patentblatt
European Patent Bulletin
Bulletin européen des brevets
DEGORCE, Sebastien, Louis, F-51689 Reims
Cedex 2, FR
LAMBERT-VAN DER BREMPT, Christine,
Marie, Paul, F-51689 Reims Cedex 2, FR
MORGENTIN, Remy, Robert, F-51689 Reims
Cedex 2, FR
PLE, Patrick, F-51689 Reims Cedex 2, FR
(74) Gairns, Raymond Stevenson, AstraZeneca
Intellectual Property AstraZeneca AB, 151 85
Sodertalje, SE
(51) C07D 311/68 (11) 2 493 871 A1*
C07D 405/04 C07D 405/14
C07D 471/04 C07D 487/04
C07D 495/04 C07D 513/04
C07D 519/00 A61K 31/473
A61P 3/10 A61P 25/28
A61P 25/22 A61P 25/14
A61P 25/16 A61P 25/18
(25) En (26) En
(21) 10781455.0 (22) 29.10.2010
(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR
GB GR HR HU IE IS IT LI LT LU LV MC MK
MT NL NO PL PT RO RS SE SI SK SM TR
(86) EP 2010/066537 29.10.2010
(87) WO 2011/051478 2011/18 05.05.2011
(30) 30.10.2009 EP 09360049
(54) NEUARTIGE OXIMDERIVATE UND IHRE
VERWENDUNG ALS ALLOSTERISCHE
MODULATOREN VON METABOTROPEN
GLUTAMATREZEPTOREN
NOVEL OXIME DERIVATIVES AND THEIR
USE AS ALLOSTERIC MODULATORS OF
METABOTROPIC GLUTAMATE
RECEPTORS
NOUVEAUX DÉRIVÉS D'OXIMES ET LEUR
UTILISATION COMME MODULATEURS
ALLOSTÉRIQUES DE RÉCEPTEURS
MÉTABOTROPIQUES DU GLUTAMATE
(71) Domain Therapeutics, Bioparc Boulevard
Sébastien Brandt, 67400 Illkirch Graffenstaden,
FR
Prestwick Chemical, Inc., Boulevard Gonthier
d'Andernach, 67400 Illkirch Graffenstaden,
FR
(72) SCHANN, Stephan, F-67400 Illkirch, FR
MAYER, Stanislas, F-67114 Eschau, FR
MORICE, Christophe, F-68320 Widensolen,
FR
GIETHLEN, Bruno, F-67120 Altorf, FR
(74) Vossius & Partner, Siebertstrasse 4, 81675
München, DE
C07D 311/76 → (51) C07D 307/58
C07D 317/58 → (51) A61P 11/06
C07D 319/14 → (51) A61P 11/06
C07D 333/52 → (51) A61P 11/06
(51) C07D 401/04 (11) 2 493 872 A1*
(25) En (26) En
(21) 10755246.5 (22) 03.09.2010
(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR
GB GR HR HU IE IS IT LI LT LU LV MC MK
MT NL NO PL PT RO SE SI SK SM TR
(86) IB 2010/053981 03.09.2010
(87) WO 2011/027326 2011/10 10.03.2011
(30) 03.09.2009 IN DE18232009
(54) VERFAHREN ZUR HERSTELLUNG VON
LENALIDOMID
PROCESS FOR THE PREPARATION OF
LENALIDOMIDE
PROCÉDÉ DE PRÉPARATION DE LÉNALI-
DOMIDE
(71) Ranbaxy Laboratories Limited, Head Office:
12th Floor Devika Tower 06 Nehru Place
New Delhi, Delhi 110019, IN
(72) KAPOOR, Munish, Punjab 143006, IN
97
Anmeldungen
Applications
Demandes (36/2012) 05.09.2012
KUMAR, Saridi, Madhava, Dileep, Haryana
122101, IN
MURUGESAN, Balaguru, Tamil Nadu
641020, IN
SATHYANARAYANA, Swargam, Karim Nagar
Andhra Pradesh 505002, IN
THAPER, Rajesh, Kumar, Jammu Jammu
and Kashmir 180001, IN
PRASAD, Mohan, Gurgaon Haryana 122001,
IN
(74) Cronin, Brian Harold John, Cronin Intellectual
Property Chemin de Précossy 31, CH-
1260 Nyon, CH
(51) C07D 401/04 (11) 2 493 873 A1*
A61K 31/416
(25) En (26) En
(21) 10759927.6 (22) 01.10.2010
(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR
GB GR HR HU IE IS IT LI LT LU LV MC MK
MT NL NO PL PT RO RS SE SI SK SM TR
(86) EP 2010/064645 01.10.2010
(87) WO 2011/042367 2011/15 14.04.2011
(30) 06.10.2009 EP 09172310
(54) FLUORIERTE 2,6-DIALKYL-3,5-DICYANO-
4-(1H-INDAZOL-5-YL)-1,4-DIHYDROPY-
RIDINE UND VERWENDUNGSVERFAH-
REN DAFÜR
FLUORINATED 2,6-DIALKYL-3,5-
DICYANO-4-(1H-INDAZOL-5-YL)-1,4-
DIHYDROPYRIDINES AND METHODS OF
USE THEREOF
2,6-DIALKYL-3,5-DICYANO-4-(1H-
INDAZOL-5-YL)-1,4-DIHYDROPYRIDINES
FLUORÉES ET LEURS PROCÉDÉS D'UTI-
LISATION
(71) Bayer Pharma Aktiengesellschaft, Müllerstrasse
178, 13353 Berlin, DE
(72) MICHELS, Martin, 51109 Köln, DE
FOLLMANN, Markus, 42489 Wülfrath, DE
VAKALOPOULOS, Alexandros, 40721 Hilden,
DE
ZIMMERMANN, Katja, 40489 Düsseldorf, DE
TEUSCH, Nicole, 42489 Wülfrath, DE
LOBELL, Mario, 42113 Wuppertal, DE
ENGEL, Karen, 42327 Wuppertal, DE
(51) C07D 401/06 (11) 2 493 874 A1*
A61K 31/496 A61P 15/06
(25) En (26) En
(21) 10807364.4 (22) 28.10.2010
(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR
GB GR HR HU IE IS IT LI LT LU LV MC MK
MT NL NO PL PT RO RS SE SI SK SM TR
(86) IB 2010/003221 28.10.2010
(87) WO 2011/051814 2011/18 05.05.2011
(30) 30.10.2009 US 256594 P
(54) NEUE KRISTALLINE FORMEN VON
(3R,6R) -3- (2, 3 -DIHYDRO- 1H- INDEN-
2 -YL) - 1 - [ (1R) - 1 - (2, 6 - DIMETHYL -
3 - PYRIDINYL) - 2 - (4 -MORPHOLINYL)
-2-OXOETHYL]-6- [(1S) - 1 -METHYL-
PROPYL]-2,5- PIPERAZINEDION
NOVEL CRYSTALLINE FORMS OF (3R,6R)
-3- (2, 3 -DIHYDRO- 1H- INDEN- 2 -YL) -
1 - [ (1R) - 1 - (2, 6 - DIMETHYL - 3 -
PYRIDINYL) - 2 - (4 -MORPHOLINYL) -2-
OXOETHYL]-6- [(1S) - 1 -METHYL-
PROPYL]-2,5- PIPERAZINEDIONE
NOUVELLES FORMES CRISTALLINES DE
(3R,6R) -3- (2, 3 -DIHYDRO- 1H- INDEN-
2 -YL) - 1 - [ (1R) - 1 - (2, 6 - DIMÉTHYL -
3 - PYRIDINYL) - 2 - (4 -MORPHOLINYL)
-2-OXOÉTHYL]-6- [(1S) - 1 -MÉTHYL-
PROPYL]-2,5- PIPÉRAZINEDIONE
(71) Glaxo Group Limited, Glaxo Wellcome House
Berkeley Avenue Greenford, Middlesex UB6
0NN, GB
(72) BELLINGHAM, Richard, Tonbridge Kent
TN11 9AN, GB