(19) 대한민국특허청(KR) (12) 공개특허공보(A) - Questel

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[1005] [1006] [1007] [1008] [1009] [1010] [1011] [1012] [1013] [1014] [1015] [1016] [1017] [1018] [1019] [1020] [1021] [1022] [1023] [1024] [1025] [1026] [1027] [1028] [1029] [1030] [1031] [1032] IQMTQSPSSLSASVGDRVTITCQASQSINNELSWYQQKPGKAPKLLIYRASTLASGVPSRFSGSGSGTDFTLTISSLQPDDFATYYCQQGYSLRNIDNA 서열 번호: 21 MDTRAPTQLLGLLLLWLPGARCAYDMTQTPASVEVAVGGTVTINCQASETIYSWLSWYQQKPGQPPKLLIYQASDLASGVPSRFSGSGAGTEYTLTISGVQC DDAATYYCQQGYSGSNVDNVFGGGTEVVVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAK 서열 번호: 22 METGLRWLLLVAVLKGVQCQEQLKESGGRLVTPGTPLTLTCTASGFSLNDHAMGWVRQAPGKGLEYIGFINSGGSARYASWAEGRFTISRTSTTVDLKMTSL TTEDTATYFCVRGGAVWSIHSFDPWGPGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVK 서열 번호: 23 QASETIYSWLS 서열 번호: 24 QASDLAS 서열 번호: 25 QQGYSGSNVDNV 서열 번호: 26 DHAMG 서열 번호: 27 FINSGGSARYASWAEG 서열 번호: 28 GGAVWSIHSFDP 서열 번호: 29 ATGGACACGAGGGCCCCCACTCAGCTGCTGGGGCTCCTGCTGCTCTGGCTCCCAGGTGCCAGATGTGCCTATGATATGACCCAGACTCCAGCCTCTGTGGAG GTAGCTGTGGGAGGCACAGTCACCATCAATTGCCAGGCCAGTGAGACCATTTACAGTTGGTTATCCTGGTATCAGCAGAAGCCAGGGCAGCCTCCCAAGCTC CTGATCTACCAGGCATCCGATCTGGCATCTGGGGTCCCATCGCGATTCAGCGGCAGTGGGGCTGGGACAGAGTACACTCTCACCATCAGCGGCGTGCAGTGT GACGATGCTGCCACTTACTACTGTCAACAGGGTTATAGTGGTAGTAATGTTGATAATGTTTTCGGCGGAGGGACCGAGGTGGTGGTCAAACGTACGGTAGCG GCCCCATCTGTCTTCATCTTCCCGCCATCTGATGAGCAGTTGAAATCTGGAACTGCCTCTGTTGTGTGCCTGCTGAATAACTTCTATCCCAGAGAGGCCAAA G 서열 번호: 30 ATGGAGACTGGGCTGCGCTGGCTTCTCCTGGTCGCTGTGCTCAAAGGTGTCCAGTGTCAGGAGCAGCTGAAGGAGTCCGGGGGTCGCCTGGTCACGCCTGGG ACACCCCTGACACTTACCTGCACAGCCTCTGGATTCTCCCTCAATGACCATGCAATGGGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAATACATCGGA TTCATTAATAGTGGTGGTAGCGCACGCTACGCGAGCTGGGCAGAAGGCCGATTCACCATCTCCAGAACCTCGACCACGGTGGATCTGAAAATGACCAGTCTG ACAACCGAGGACACGGCCACCTATTTCTGTGTCAGAGGGGGTGCTGTTTGGAGTATTCATAGTTTTGATCCCTGGGGCCCAGGGACCCTGGTCACCGTCTCG AGCGCCTCCACCAAGGGCCCATCGGTCTTCCCCCTGGCACCCTCCTCCAAGAGCACCTCTGGGGGCACAGCGGCCCTGGGCTGCCTGGTCAAG 서열 번호: 31 CAGGCCAGTGAGACCATTTACAGTTGGTTATCC 서열 번호: 32 CAGGCATCCGATCTGGCATCT 서열 번호: 33 CAACAGGGTTATAGTGGTAGTAATGTTGATAATGTT 서열 번호: 34 - 136 - 공개특허 10-2011-0112308
[1033] [1034] [1035] [1036] [1037] [1038] [1039] [1040] [1041] [1042] [1043] [1044] [1045] [1046] [1047] [1048] [1049] [1050] [1051] [1052] [1053] [1054] [1055] [1056] [1057] [1058] [1059] [1060] [1061] GACCATGCAATGGGC 서열 번호: 35 TTCATTAATAGTGGTGGTAGCGCACGCTACGCGAGCTGGGCAGAAGGC 서열 번호: 36 GGGGGTGCTGTTTGGAGTATTCATAGTTTTGATCCC 서열 번호: 37 MDTRAPTQLLGLLLLWLPGATFAAVLTQTPSPVSAAVGGTVSISCQASQSVYDNNYLSWFQQKPGQPPKLLIYGASTLASGVPSRFVGSGSGTQFTLTITDV QCDDAATYYCAGVYDDDSDNAFGGGTEVVVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNF 서열 번호: 38 METGLRWLLLVAVLKGVQCQSLEESGGRLVTPGTPLTLTCTASGFSLSVYYMNWVRQAPGKGLEWIGFITMSDNINYASWAKGRFTISKTSTTVDLKMTSPT TEDTATYFCARSRGWGTMGRLDLWGPGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVK 서열 번호: 39 QASQSVYDNNYLS 서열 번호: 40 GASTLAS 서열 번호: 41 AGVYDDDSDNA 서열 번호: 42 VYYMN 서열 번호: 43 FITMSDNINYASWAKG 서열 번호: 44 SRGWGTMGRLDL 서열 번호: 45 ATGGACACGAGGGCCCCCACTCAGCTGCTGGGGCTCCTGCTGCTCTGGCTCCCAGGTGCCACATTTGCCGCCGTGCTGACCCAGACTCCATCTCCCGTGTCT GCAGCTGTGGGAGGCACAGTCAGCATCAGTTGCCAGGCCAGTCAGAGTGTTTATGACAACAACTACTTATCCTGGTTTCAGCAGAAACCAGGGCAGCCTCCC AAGCTCCTGATCTATGGTGCATCCACTCTGGCATCTGGGGTCCCATCGCGGTTCGTGGGCAGTGGATCTGGGACACAGTTCACTCTCACCATCACAGACGTG CAGTGTGACGATGCTGCCACTTACTATTGTGCAGGCGTTTATGATGATGATAGTGATAATGCCTTCGGCGGAGGGACCGAGGTGGTGGTCAAACGTACGGTA GCGGCCCCATCTGTCTTCATCTTCCCGCCATCTGATGAGCAGTTGAAATCTGGAACTGCCTCTGTTGTGTGCCTGCTGAATAACTTCT 서열 번호: 46 ATGGAGACTGGGCTGCGCTGGCTTCTCCTGGTGGCTGTGCTCAAAGGTGTCCAGTGTCAGTCGCTGGAGGAGTCCGGGGGTCGCCTGGTCACCCCTGGGACA CCCCTGACACTCACCTGCACAGCCTCTGGATTCTCCCTCAGTGTCTACTACATGAACTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAATGGATCGGATTC ATTACAATGAGTGATAATATAAATTACGCGAGCTGGGCGAAAGGCCGATTCACCATCTCCAAAACCTCGACCACGGTGGATCTGAAAATGACCAGTCCGACA ACCGAGGACACGGCCACCTATTTCTGTGCCAGGAGTCGTGGCTGGGGTACAATGGGTCGGTTGGATCTCTGGGGCCCAGGCACCCTCGTCACCGTCTCGAGC GCCTCCACCAAGGGCCCATCGGTCTTCCCCCTGGCACCCTCCTCCAAGAGCACCTCTGGGGGCACAGCGGCCCTGGGCTGCCTGGTCAAGG 서열 번호: 47 CAGGCCAGTCAGAGTGTTTATGACAACAACTACTTATCC 서열 번호: 48 GGTGCATCCACTCTGGCATCT - 137 - 공개특허 10-2011-0112308
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(51) Int. Cl. (19) 대한민국특
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특허청구의 범위 청구항 1
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서열 번호: 5에 적어도 85.7%
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청구항 1 내지 20중 어느 한
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청구항 38 청구항 34에 있어
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암(Pharyngeal Cancer), 갈색세
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청구항 41에 있어서, Ab1 항
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청구항 41에 있어서, 개체
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청구항 103에 있어서, 항-IL-
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톨페남산, 톨메틴, 발데콕
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IFN-감마, BAFF, CXCL13, IP-10, VE
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드, 또는 높은 엄밀도 조건
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서열 번호: 120에 적어도 50%
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청구항 160 청구항 140 내지
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약, 항히스타민제, 아프레
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탈리주맙, 네다플라틴, 네
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[0001] [0002] [0003] [0004] [0005]
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[0015] [0016] [0017] [0018] [0019]
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[0029] [0030] [0031] [0032] [0033]
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[0040] [0041] [0042] [0043] [0044]
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[0056] [0057] [0058] [0059] [0060]
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[0084] [0085] [0086] [0087] [0088]
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[0100] [0101] [0102] [0103] [0104]
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[0132] [0133] [0134] [0135] [0136]
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[0171] [0172] [0173] [0174] [0175]
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[0186] [0187] [0188] [0189] 한 참
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[0197] [0198] [0199] [0200] [0201]
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[0210] [0211] [0212] [0213] [0214]
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[0228] [0229] [0230] [0231] [0232]
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[0242] [0243] [0244] [0245] [0246]
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[0254] [0255] [0256] [0257] [0258]
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[0276] [0277] [0278] [0279] [0280]
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[0301] [0302] [0303] [0304] [0305]
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[0363] [0364] [0365] [0366] [0367]
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[0405] [0406] [0407] [0408] [0409]
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[0411] [0412] [0413] [0414] [0415]
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[0425] [0426] [0427] [0428] [0429]
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[0438] [0439] [0440] [0441] [0442]
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[0455] [0456] [0457] [0458] [0459]
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[0463] [0464] [0465] 333, 525 415,
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[0474] [0475] [0476] [0477] [0478]
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[0495] [0496] [0497] [0498] [0499]
Page 85 and 86: [0520] [0521] [0522] [0523] [0524]
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Page 99 and 100: [0664] [0665] [0666] [0667] [0668]
Page 101 and 102: [0684] [0685] challenge to evaluate
Page 103 and 104: [0686] [0687] marrow transplantatio
Page 105 and 106: [0688] prostate cancer xenografts i
Page 107 and 108: [0689] [0690] [0691] [0692] [0693]
Page 109 and 110: [0699] [0700] [0701] [0702] [0703]
Page 111 and 112: 도 4에서는 인간 IL-6의 100
Page 113 and 114: [0718] [0719] [0720] [0721] [0722]
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Page 117 and 118: [0751] [0752] [0753] [0754] [0755]
Page 119 and 120: [0771] [0772] [0773] [0774] [0775]
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Page 165 and 166: [1877] [1878] [1879] [1880] [1881]
Page 167 and 168: [1937] [1938] [1939] [1940] [1941]
Page 169 and 170: [1997] [1998] [1999] [2000] [2001]
Page 171 and 172: [2059] [2060] [2061] [2062] [2063]
Page 173 and 174: [2121] [2122] [2123] [2124] [2125]
Page 175 and 176: [2177] [2178] [2179] [2180] [2181]
Page 177 and 178: [2249] [2250] [2251] [2252] [2253]
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Page 185 and 186: [2418] [2419] [2420] [2421] 서열
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도면2 - 187 - 공개특허 10-201
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도면4 - 189 - 공개특허 10-201
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도면6 - 191 - 공개특허 10-201
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도면8 - 193 - 공개특허 10-201
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도면10a - 195 - 공개특허 10-2
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도면10c - 197 - 공개특허 10-2
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도면10e - 199 - 공개특허 10-2
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도면12 - 201 - 공개특허 10-20
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도면14 - 203 - 공개특허 10-20
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도면16 - 205 - 공개특허 10-20
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도면18 - 207 - 공개특허 10-20
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도면20 - 209 - 공개특허 10-20
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도면22 - 211 - 공개특허 10-20
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도면24 - 213 - 공개특허 10-20
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도면26a 도면26b - 215 - 공개
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도면28 - 217 - 공개특허 10-20
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도면30 도면31 - 219 - 공개특
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도면33 - 221 - 공개특허 10-20
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도면35 - 223 - 공개특허 10-20
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도면36b - 225 - 공개특허 10-2
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도면37b - 227 - 공개특허 10-2
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도면39 - 229 - 공개특허 10-20
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도면41 - 231 - 공개특허 10-20
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도면43 - 233 - 공개특허 10-20
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도면45 - 235 - 공개특허 10-20
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도면47 - 237 - 공개특허 10-20
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도면49 - 239 - 공개특허 10-20
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도면51 - 241 - 공개특허 10-20
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도면53 - 243 - 공개특허 10-20
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도면56 도면57 - 245 - 공개특
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도면60 도면61 - 247 - 공개특
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Smith, Jeffrey T.L. Schatzman, Rand
Page 251 and 252:
Leu Pro Gly Ala Arg Cys Ala Tyr Asp
Page 253 and 254:
PRT Oryctolagus cuniculus 6 Gln G
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agggcatcca ctctggcatc t 21 14 36
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99 PRT Oryctolagus cuniculus 20
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100 105 110 Val Arg Gly Gly Ala Val
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501 DNA Oryctolagus cuniculus 30
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85 90 95 Leu Thr Ile Thr Asp Val Gl
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1 5 43 16 PRT Oryctolagus cunic
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gtctactaca tgaac 15 51 48 DNA O
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145 150 155 160 Ala Leu Gly Cys Leu
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gagcagctga aggagtccgg aggaggcctg gt
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Val Val Val Lys Arg Thr Val Ala Ala
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75 Ile Ile Gly Gly Phe Gly Thr Thr
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Oryctolagus cuniculus 83 atcattggt
Page 279 and 280:
Page 281 and 282:
tgggcgaaag gccgattcac catctccaaa ac
Page 283 and 284:
145 150 155 160 Leu Asn Asn Phe 10
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108 12 PRT Oryctolagus cuniculus
Page 287 and 288:
Page 289 and 290:
PRT Oryctolagus cuniculus 120 Ile
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125 Glu Ile Ser Lys Leu Glu Ser 1 5
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133 gaaatatcca aactggaatc t 21 134
Page 295 and 296:
100 105 110 Val Arg Ser Leu Lys Tyr
Page 297 and 298:
gcgaaaggcc gattcaccat ctccaagacc tc
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1 5 10 15 Val Gln Cys Gln Ser Val G
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gtcaccatca gttgccagtc cagtcagagt gt
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50 55 60 Gly Gln Arg Pro Lys Leu Le
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Page 307 and 308:
aattatggtg gtgatgaaag tttg 24 186
Page 309 and 310:
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Oryctolagus cuniculus 199 agcggcta
Page 313 and 314:
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213 21 DNA Oryctolagus cuniculus
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65 70 75 80 Ala Lys Gly Arg Phe Thr
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100 105 110 Leu Gly Ser Tyr Asp Cys
Page 323 and 324:
Ala Tyr Asp Leu 1 242 375 DNA O
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Met Asp Thr Arg Ala Pro Thr Gln Leu
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1 5 256 16 PRT Oryctolagus cuni
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DNA Oryctolagus cuniculus 264 ttc
Page 331 and 332:
Trp Ala Ser Thr Leu Ala Ser 1 5 27
Page 333 and 334:
Page 335 and 336:
284 11 PRT 115 120 125 Oryctolag
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tacgcgagtt gggcgaaagg ccgattcacc at
Page 339 and 340:
1 5 10 15 Val Gln Cys Gln Ser Val G
Page 341 and 342:
aaaccagggc agcctcccaa gctcctgatc ta
Page 343 and 344:
65 70 75 80 Gly Val Pro Ser Arg Phe
Page 345 and 346:
Page 347 and 348:
gtcattggcg atactgctgg ttatgcttat tt
Page 349 and 350:
1 5 10 < 210> 335 5 PRT Oryctola
Page 351 and 352:
Page 353 and 354:
Oryctolagus cuniculus 348 Gln Ala
Page 355 and 356:
Oryctolagus cuniculus 356 caggccag
Page 357 and 358:
Ser Thr Tyr Tyr Ile Tyr Trp Val Arg
Page 359 and 360:
gacctggagt gtgacgatgc tgccacttac ta
Page 361 and 362:
Pro Ser Arg Phe Lys Gly Ser Gly Ser
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DNA Oryctolagus cuniculus 407 agc
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1 5 10 413 7 PRT Oryctolagus cu
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65 70 75 80 Ala Lys Gly Arg Phe Thr
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atggagactg ggctgcgctg gcttctcctg gt
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450 atggacacga gggcccccac tcagctgct
Page 383 and 384:
Val Ser Ala Ala Val Gly Gly Thr Val
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Ile Ile Ala Asn Ser Gly Thr Thr Phe
Page 387 and 388:
DNA Oryctolagus cuniculus 473 gag
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478 Gln Gln Gly Ala Thr Val Tyr Asp
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492 Gln Ala Ser Glu Asn Ile Tyr Ser
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500 caggccagtg agaacattta tagcttttt
Page 397 and 398:
50 55 60 Trp Ile Gly Ile Ile Thr Gl
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Oryctolagus cuniculus 515 atggagac
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523 122 PRT 115 120 Oryctolagus
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DNA Oryctolagus cuniculus 530 atg
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20 25 30 Val Ser Val Pro Val Gly As
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Oryctolagus cuniculus 544 Phe Ile
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Oryctolagus cuniculus 558 Gln Gln
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Oryctolagus cuniculus 566 caacaggg
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PRT Oryctolagus cuniculus 572 Gln
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DNA Oryctolagus cuniculus 580 cag
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aacaggggag agtgt 315 588 330 PRT
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tacgtggacg gcgtggaggt gcataatgcc aa
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15 PRT Homo sapiens 598 Asp Lys
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Ser Lys Glu Ala Leu Ala Glu Asn Asn
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15 PRT Homo sapiens 617 Cys Leu
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626 Glu Gln Ala Arg Ala Val Gln Met
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15 PRT Homo sapiens 636 Asp Pro
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645 Leu Arg Ser Phe Lys Glu Phe Leu
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PRT Homo sapiens 650 Asp Ile Gln
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20 25 30 Tyr Met Ser Trp Val Arg Gl
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65 70 75 80 Gln Met Asn Ser Leu Arg
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gcaaaattta acttg 375 664 450 PRT
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450 665 450 PRT Oryctolagus cun
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Gly Lys 450 666 216 PRT Oryctol
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20 25 30 Pro Gly Thr Pro Leu Thr Le
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1 5 10 15 Val Gln Cys Gln Ser Leu G
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676 Met Glu Thr Gly Leu Arg Trp Leu
Page 455 and 456:
PRT Oryctolagus cuniculus 680 Met
Page 457 and 458:
684 128 PRT 115 120 Oryctolagus
Page 459 and 460:
100 105 110 Gly Tyr Ser Leu Arg Asn
Page 461 and 462:
85 90 95 Arg Asp Asp Ser Ser Asp Tr
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85 90 95 Arg Asp Asp Ser Ser Asp Tr
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85 90 95 Ile Asp Asn Ala Phe Gly Gl
Page 467 and 468:
50 55 60 Ser Gly Ser Gly Thr Asp Ph
Page 469 and 470:
Lys Val Tyr Ala Cys Glu Val Thr His
Page 471 and 472:
195 200 205 Pro Ser Asn Thr Lys Val
Page 473 and 474:
Leu Ile Tyr Arg Ala Ser Thr Leu Ala
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50 55 60 Trp Val Gly Ile Ile Tyr Gl
Page 477 and 478:
35 40 45 Tyr Arg Ala Ser Thr Leu Al
Page 479 and 480:
212> PRT Homo sapiens 718 Val Ile
Page 481 and 482:
ttcagcggca gtggatctgg gacagacttc ac
Page 483 and 484:
PRT Homo sapiens 726 Met Glu Lys
Page 485 and 486:
210 215 220 Thr Ala Val Ala Arg Asn
Page 487 and 488:
195 200 205 Ser Asp His Ile Asn Phe
Page 489:
690 695 700 Pro Glu Asp Leu Lys Ser
show all

(19) 대한민국특허청(KR) (12) 공개특허공보(A) - Questel

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