(19) 대한민국특허청(KR) (12) 공개특허공보(A) - Questel

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Homo sapiens 612 Ala Glu Lys Asp Gly Cys Phe Gln Ser Gly Phe Asn Glu Glu Thr 1 5 10 15 613 15 PRT Homo sapiens 613 Asp Gly Cys Phe Gln Ser Gly Phe Asn Glu Glu Thr Cys Leu Val 1 5 10 15 614 15 PRT Homo sapiens 614 Phe Gln Ser Gly Phe Asn Glu Glu Thr Cys Leu Val Lys Ile Ile 1 5 10 15 615 15 PRT Homo sapiens 615 Gly Phe Asn Glu Glu Thr Cys Leu Val Lys Ile Ile Thr Gly Leu 1 5 10 15 616 15 PRT Homo sapiens 616 Glu Glu Thr Cys Leu Val Lys Ile Ile Thr Gly Leu Leu Glu Phe 1 5 10 15 617 - 426 - 공개특허 10-2011-0112308
15 PRT Homo sapiens 617 Cys Leu Val Lys Ile Ile Thr Gly Leu Leu Glu Phe Glu Val Tyr 1 5 10 15 618 15 PRT Homo sapiens 618 Lys Ile Ile Thr Gly Leu Leu Glu Phe Glu Val Tyr Leu Glu Tyr 1 5 10 15 619 15 PRT Homo sapiens 619 Thr Gly Leu Leu Glu Phe Glu Val Tyr Leu Glu Tyr Leu Gln Asn 1 5 10 15 620 15 PRT Homo sapiens 620 Leu Glu Phe Glu Val Tyr Leu Glu Tyr Leu Gln Asn Arg Phe Glu 1 5 10 15 621 15 PRT Homo sapiens 621 Glu Val Tyr Leu Glu Tyr Leu Gln Asn Arg Phe Glu Ser Ser Glu - 427 - 공개특허 10-2011-0112308
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(51) Int. Cl. (19) 대한민국특
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특허청구의 범위 청구항 1
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서열 번호: 5에 적어도 85.7%
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청구항 1 내지 20중 어느 한
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청구항 38 청구항 34에 있어
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암(Pharyngeal Cancer), 갈색세
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청구항 41에 있어서, Ab1 항
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청구항 41에 있어서, 개체
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청구항 103에 있어서, 항-IL-
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톨페남산, 톨메틴, 발데콕
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IFN-감마, BAFF, CXCL13, IP-10, VE
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드, 또는 높은 엄밀도 조건
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서열 번호: 120에 적어도 50%
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청구항 160 청구항 140 내지
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약, 항히스타민제, 아프레
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탈리주맙, 네다플라틴, 네
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[0001] [0002] [0003] [0004] [0005]
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[0015] [0016] [0017] [0018] [0019]
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[0029] [0030] [0031] [0032] [0033]
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[0040] [0041] [0042] [0043] [0044]
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[0056] [0057] [0058] [0059] [0060]
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[0084] [0085] [0086] [0087] [0088]
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[0100] [0101] [0102] [0103] [0104]
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[0132] [0133] [0134] [0135] [0136]
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[0171] [0172] [0173] [0174] [0175]
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[0186] [0187] [0188] [0189] 한 참
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[0197] [0198] [0199] [0200] [0201]
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[0210] [0211] [0212] [0213] [0214]
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[0228] [0229] [0230] [0231] [0232]
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[0242] [0243] [0244] [0245] [0246]
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[0254] [0255] [0256] [0257] [0258]
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[0276] [0277] [0278] [0279] [0280]
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[0301] [0302] [0303] [0304] [0305]
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[0363] [0364] [0365] [0366] [0367]
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[0405] [0406] [0407] [0408] [0409]
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[0411] [0412] [0413] [0414] [0415]
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[0425] [0426] [0427] [0428] [0429]
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[0438] [0439] [0440] [0441] [0442]
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[0455] [0456] [0457] [0458] [0459]
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[0463] [0464] [0465] 333, 525 415,
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[0495] [0496] [0497] [0498] [0499]
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[0609] [0610] [0611] [0612] [0613]
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[0623] [0624] [0625] [0626] [0627]
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[0641] [0642] [0643] [0644] [0645]
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[0664] [0665] [0666] [0667] [0668]
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[0684] [0685] challenge to evaluate
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[0686] [0687] marrow transplantatio
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[0688] prostate cancer xenografts i
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[0689] [0690] [0691] [0692] [0693]
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[0699] [0700] [0701] [0702] [0703]
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도 4에서는 인간 IL-6의 100
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[0718] [0719] [0720] [0721] [0722]
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[0737] [0738] [0739] [0740] [0741]
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[0751] [0752] [0753] [0754] [0755]
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[0771] [0772] [0773] [0774] [0775]
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[0793] [0794] [0795] [0796] [0797]
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[0815] [0816] [0817] [0818] [0819]
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[0838] [0839] [0840] [0841] [0842]
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[0868] [0869] [0870] [0871] [0872]
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[0893] [0894] [0895] [0896] [0897]
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[1391] [1392] [1393] [1394] [1395]
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[1817] [1818] [1819] [1820] [1821]
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[1877] [1878] [1879] [1880] [1881]
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[1937] [1938] [1939] [1940] [1941]
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[1997] [1998] [1999] [2000] [2001]
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[2059] [2060] [2061] [2062] [2063]
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[2121] [2122] [2123] [2124] [2125]
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[2177] [2178] [2179] [2180] [2181]
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[2249] [2250] [2251] [2252] [2253]
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[2302] [2303] [2304] [2305] [2306]
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[2378] [2379] [2380] [2381] [2382]
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[2418] [2419] [2420] [2421] 서열
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도면2 - 187 - 공개특허 10-201
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도면4 - 189 - 공개특허 10-201
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도면6 - 191 - 공개특허 10-201
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도면8 - 193 - 공개특허 10-201
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도면10a - 195 - 공개특허 10-2
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도면10c - 197 - 공개특허 10-2
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도면10e - 199 - 공개특허 10-2
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도면12 - 201 - 공개특허 10-20
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도면14 - 203 - 공개특허 10-20
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도면16 - 205 - 공개특허 10-20
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도면18 - 207 - 공개특허 10-20
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도면20 - 209 - 공개특허 10-20
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도면22 - 211 - 공개특허 10-20
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도면24 - 213 - 공개특허 10-20
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도면26a 도면26b - 215 - 공개
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도면28 - 217 - 공개특허 10-20
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도면30 도면31 - 219 - 공개특
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도면33 - 221 - 공개특허 10-20
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도면35 - 223 - 공개특허 10-20
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도면36b - 225 - 공개특허 10-2
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도면37b - 227 - 공개특허 10-2
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도면39 - 229 - 공개특허 10-20
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도면41 - 231 - 공개특허 10-20
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도면43 - 233 - 공개특허 10-20
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도면45 - 235 - 공개특허 10-20
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도면47 - 237 - 공개특허 10-20
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도면49 - 239 - 공개특허 10-20
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도면51 - 241 - 공개특허 10-20
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도면53 - 243 - 공개특허 10-20
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도면56 도면57 - 245 - 공개특
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도면60 도면61 - 247 - 공개특
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Smith, Jeffrey T.L. Schatzman, Rand
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Leu Pro Gly Ala Arg Cys Ala Tyr Asp
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PRT Oryctolagus cuniculus 6 Gln G
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agggcatcca ctctggcatc t 21 14 36
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99 PRT Oryctolagus cuniculus 20
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100 105 110 Val Arg Gly Gly Ala Val
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501 DNA Oryctolagus cuniculus 30
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85 90 95 Leu Thr Ile Thr Asp Val Gl
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1 5 43 16 PRT Oryctolagus cunic
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gtctactaca tgaac 15 51 48 DNA O
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145 150 155 160 Ala Leu Gly Cys Leu
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gagcagctga aggagtccgg aggaggcctg gt
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Val Val Val Lys Arg Thr Val Ala Ala
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75 Ile Ile Gly Gly Phe Gly Thr Thr
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Oryctolagus cuniculus 83 atcattggt
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tgggcgaaag gccgattcac catctccaaa ac
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145 150 155 160 Leu Asn Asn Phe 10
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108 12 PRT Oryctolagus cuniculus
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PRT Oryctolagus cuniculus 120 Ile
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125 Glu Ile Ser Lys Leu Glu Ser 1 5
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133 gaaatatcca aactggaatc t 21 134
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100 105 110 Val Arg Ser Leu Lys Tyr
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gcgaaaggcc gattcaccat ctccaagacc tc
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1 5 10 15 Val Gln Cys Gln Ser Val G
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gtcaccatca gttgccagtc cagtcagagt gt
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50 55 60 Gly Gln Arg Pro Lys Leu Le
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aattatggtg gtgatgaaag tttg 24 186
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Oryctolagus cuniculus 199 agcggcta
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213 21 DNA Oryctolagus cuniculus
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65 70 75 80 Ala Lys Gly Arg Phe Thr
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100 105 110 Leu Gly Ser Tyr Asp Cys
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Ala Tyr Asp Leu 1 242 375 DNA O
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Met Asp Thr Arg Ala Pro Thr Gln Leu
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1 5 256 16 PRT Oryctolagus cuni
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DNA Oryctolagus cuniculus 264 ttc
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Trp Ala Ser Thr Leu Ala Ser 1 5 27
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284 11 PRT 115 120 125 Oryctolag
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tacgcgagtt gggcgaaagg ccgattcacc at
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1 5 10 15 Val Gln Cys Gln Ser Val G
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aaaccagggc agcctcccaa gctcctgatc ta
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65 70 75 80 Gly Val Pro Ser Arg Phe
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gtcattggcg atactgctgg ttatgcttat tt
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1 5 10 < 210> 335 5 PRT Oryctola
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Oryctolagus cuniculus 348 Gln Ala
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Oryctolagus cuniculus 356 caggccag
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Ser Thr Tyr Tyr Ile Tyr Trp Val Arg
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gacctggagt gtgacgatgc tgccacttac ta
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Pro Ser Arg Phe Lys Gly Ser Gly Ser
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DNA Oryctolagus cuniculus 407 agc
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1 5 10 413 7 PRT Oryctolagus cu
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Page 375 and 376: 65 70 75 80 Ala Lys Gly Arg Phe Thr
Page 377 and 378: atggagactg ggctgcgctg gcttctcctg gt
Page 379 and 380: 127 PRT Oryctolagus cuniculus 44
Page 381 and 382: 450 atggacacga gggcccccac tcagctgct
Page 383 and 384: Val Ser Ala Ala Val Gly Gly Thr Val
Page 385 and 386: Ile Ile Ala Asn Ser Gly Thr Thr Phe
Page 387 and 388: DNA Oryctolagus cuniculus 473 gag
Page 389 and 390: 478 Gln Gln Gly Ala Thr Val Tyr Asp
Page 391 and 392: 487 15 DNA Oryctolagus cuniculus
Page 393 and 394: 492 Gln Ala Ser Glu Asn Ile Tyr Ser
Page 395 and 396: 500 caggccagtg agaacattta tagcttttt
Page 397 and 398: 50 55 60 Trp Ile Gly Ile Ile Thr Gl
Page 399 and 400: Oryctolagus cuniculus 515 atggagac
Page 401 and 402: 523 122 PRT 115 120 Oryctolagus
Page 403 and 404: DNA Oryctolagus cuniculus 530 atg
Page 405 and 406: 20 25 30 Val Ser Val Pro Val Gly As
Page 407 and 408: Oryctolagus cuniculus 544 Phe Ile
Page 409 and 410: 553 33 DNA Oryctolagus cuniculus
Page 411 and 412: Oryctolagus cuniculus 558 Gln Gln
Page 413 and 414: Oryctolagus cuniculus 566 caacaggg
Page 415 and 416: PRT Oryctolagus cuniculus 572 Gln
Page 417 and 418: DNA Oryctolagus cuniculus 580 cag
Page 419 and 420: aacaggggag agtgt 315 588 330 PRT
Page 421 and 422: tacgtggacg gcgtggaggt gcataatgcc aa
Page 423 and 424: 15 PRT Homo sapiens 598 Asp Lys
Page 425: Ser Lys Glu Ala Leu Ala Glu Asn Asn
Page 429 and 430: 626 Glu Gln Ala Arg Ala Val Gln Met
Page 431 and 432: 15 PRT Homo sapiens 636 Asp Pro
Page 433 and 434: 645 Leu Arg Ser Phe Lys Glu Phe Leu
Page 435 and 436: PRT Homo sapiens 650 Asp Ile Gln
Page 437 and 438: 20 25 30 Tyr Met Ser Trp Val Arg Gl
Page 439 and 440: 65 70 75 80 Gln Met Asn Ser Leu Arg
Page 441 and 442: 122 PRT Oryctolagus cuniculus 66
Page 443 and 444: gcaaaattta acttg 375 664 450 PRT
Page 445 and 446: 450 665 450 PRT Oryctolagus cun
Page 447 and 448: Gly Lys 450 666 216 PRT Oryctol
Page 449 and 450: 20 25 30 Pro Gly Thr Pro Leu Thr Le
Page 451 and 452: 1 5 10 15 Val Gln Cys Gln Ser Leu G
Page 453 and 454: 676 Met Glu Thr Gly Leu Arg Trp Leu
Page 455 and 456: PRT Oryctolagus cuniculus 680 Met
Page 457 and 458: 684 128 PRT 115 120 Oryctolagus
Page 459 and 460: 100 105 110 Gly Tyr Ser Leu Arg Asn
Page 461 and 462: 85 90 95 Arg Asp Asp Ser Ser Asp Tr
Page 463 and 464: 85 90 95 Arg Asp Asp Ser Ser Asp Tr
Page 465 and 466: 85 90 95 Ile Asp Asn Ala Phe Gly Gl
Page 467 and 468: 50 55 60 Ser Gly Ser Gly Thr Asp Ph
Page 469 and 470: Lys Val Tyr Ala Cys Glu Val Thr His
Page 471 and 472: 195 200 205 Pro Ser Asn Thr Lys Val
Page 473 and 474: Leu Ile Tyr Arg Ala Ser Thr Leu Ala
Page 475 and 476: 50 55 60 Trp Val Gly Ile Ile Tyr Gl
Page 477 and 478:
35 40 45 Tyr Arg Ala Ser Thr Leu Al
Page 479 and 480:
212> PRT Homo sapiens 718 Val Ile
Page 481 and 482:
ttcagcggca gtggatctgg gacagacttc ac
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PRT Homo sapiens 726 Met Glu Lys
Page 485 and 486:
210 215 220 Thr Ala Val Ala Arg Asn
Page 487 and 488:
195 200 205 Ser Asp His Ile Asn Phe
Page 489:
690 695 700 Pro Glu Asp Leu Lys Ser
show all

(19) 대한민국특허청(KR) (12) 공개특허공보(A) - Questel

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