(19) 대한민국특허청(KR) (12) 공개특허공보(A) - Questel

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Oryctolagus cuniculus 723 gctatccaga tgacccagtc tccttcctcc ctgtctgcat ctgtaggaga cagagtcacc 60 atcacttgcc aggccagtca gagcattaac aatgagttat cctggtatca gcagaaacca 120 gggaaagccc ctaagctcct gatctatagg gcatccactc tggcatctgg ggtcccatca 180 aggttcagcg gcagtggatc tgggacagac ttcactctca ccatcagcag cctgcagcct 240 gatgattttg caacttatta ctgccaacag ggttatagtc tgaggaacat tgataatgct 300 ttcggcggag ggaccaaggt ggaaatcaaa cgt 333 724 327 DNA Oryctolagus cuniculus 724 gaggtgcagc tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt ctccctcagt aactactacg tgacctgggt ccgtcaggct 120 ccagggaagg ggctggagtg ggtcggcatc atctatggta gtgatgaaac cgcctacgct 180 acctccgcta taggccgatt caccatctcc agagacaatt ccaagaacac cctgtatctt 240 caaatgaaca gcctgagagc tgaggacact gctgtgtatt actgtgctag agatgatagt 300 agtgactggg atgcaaagtt caacttg 327 725 351 DNA Oryctolagus cuniculus 725 cagtcgctgg aggagtccgg gggtcgcctg gtcacgcctg ggacacccct gacactcacc 60 tgcacagcct ctggattctc cctcagtaac tactacgtga cctgggtccg ccaggctcca 120 gggaaggggc tggaatggat cggaatcatt tatggtagtg atgaaacggc ctacgcgacc 180 tgggcgatag gccgattcac catctccaaa acctcgacca cggtggatct gaaaatgacc 240 agtctgacag ccgcggacac ggccacctat ttctgtgcca gagatgatag tagtgactgg 300 gatgcaaaat ttaacttgtg gggccaaggc accctggtca ccgtctcgag c 351 726 224 - 482 - 공개특허 10-2011-0112308
PRT Homo sapiens 726 Met Glu Lys Leu Leu Cys Phe Leu Val Leu Thr Ser Leu Ser His Ala 1 5 10 15 Phe Gly Gln Thr Asp Met Ser Arg Lys Ala Phe Val Phe Pro Lys Glu 20 25 30 Ser Asp Thr Ser Tyr Val Ser Leu Lys Ala Pro Leu Thr Lys Pro Leu 35 40 45 Lys Ala Phe Thr Val Cys Leu His Phe Tyr Thr Glu Leu Ser Ser Thr 50 55 60 Arg Gly Tyr Ser Ile Phe Ser Tyr Ala Thr Lys Arg Gln Asp Asn Glu 65 70 75 80 Ile Leu Ile Phe Trp Ser Lys Asp Ile Gly Tyr Ser Phe Thr Val Gly 85 90 95 Gly Ser Glu Ile Leu Phe Glu Val Pro Glu Val Thr Val Ala Pro Val 100 105 110 His Ile Cys Thr Ser Trp Glu Ser Ala Ser Gly Ile Val Glu Phe Trp 115 120 125 Val Asp Gly Lys Pro Arg Val Arg Lys Ser Leu Lys Lys Gly Tyr Thr 130 135 140 Val Gly Ala Glu Ala Ser Ile Ile Leu Gly Gln Glu Gln Asp Ser Phe 145 150 155 160 Gly Gly Asn Phe Glu Gly Ser Gln Ser Leu Val Gly Asp Ile Gly Asn 165 170 175 Val Asn Met Trp Asp Phe Val Leu Ser Pro Asp Glu Ile Asn Thr Ile 180 185 190 Tyr Leu Gly Gly Pro Phe Ser Pro Asn Val Leu Asn Trp Arg Ala Leu 195 200 205 Lys Tyr Glu Val Gln Gly Glu Val Phe Thr Lys Pro Gln Leu Trp Pro 210 215 220 727 - 483 - 공개특허 10-2011-0112308
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(51) Int. Cl. (19) 대한민국특
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특허청구의 범위 청구항 1
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서열 번호: 5에 적어도 85.7%
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청구항 1 내지 20중 어느 한
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청구항 38 청구항 34에 있어
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암(Pharyngeal Cancer), 갈색세
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청구항 41에 있어서, Ab1 항
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청구항 41에 있어서, 개체
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청구항 103에 있어서, 항-IL-
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톨페남산, 톨메틴, 발데콕
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IFN-감마, BAFF, CXCL13, IP-10, VE
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드, 또는 높은 엄밀도 조건
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서열 번호: 120에 적어도 50%
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청구항 160 청구항 140 내지
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약, 항히스타민제, 아프레
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탈리주맙, 네다플라틴, 네
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[0001] [0002] [0003] [0004] [0005]
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[0015] [0016] [0017] [0018] [0019]
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[0029] [0030] [0031] [0032] [0033]
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[0040] [0041] [0042] [0043] [0044]
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[0056] [0057] [0058] [0059] [0060]
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[0084] [0085] [0086] [0087] [0088]
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[0100] [0101] [0102] [0103] [0104]
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[0132] [0133] [0134] [0135] [0136]
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[0171] [0172] [0173] [0174] [0175]
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[0186] [0187] [0188] [0189] 한 참
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[0197] [0198] [0199] [0200] [0201]
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[0210] [0211] [0212] [0213] [0214]
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[0228] [0229] [0230] [0231] [0232]
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[0242] [0243] [0244] [0245] [0246]
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[0254] [0255] [0256] [0257] [0258]
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[0276] [0277] [0278] [0279] [0280]
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[0301] [0302] [0303] [0304] [0305]
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[0363] [0364] [0365] [0366] [0367]
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[0405] [0406] [0407] [0408] [0409]
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[0411] [0412] [0413] [0414] [0415]
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[0425] [0426] [0427] [0428] [0429]
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[0438] [0439] [0440] [0441] [0442]
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[0455] [0456] [0457] [0458] [0459]
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[0463] [0464] [0465] 333, 525 415,
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[0474] [0475] [0476] [0477] [0478]
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[0495] [0496] [0497] [0498] [0499]
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[0609] [0610] [0611] [0612] [0613]
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[0623] [0624] [0625] [0626] [0627]
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[0641] [0642] [0643] [0644] [0645]
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[0664] [0665] [0666] [0667] [0668]
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[0684] [0685] challenge to evaluate
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[0686] [0687] marrow transplantatio
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[0688] prostate cancer xenografts i
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[0689] [0690] [0691] [0692] [0693]
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[0699] [0700] [0701] [0702] [0703]
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도 4에서는 인간 IL-6의 100
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[0718] [0719] [0720] [0721] [0722]
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[0737] [0738] [0739] [0740] [0741]
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[0751] [0752] [0753] [0754] [0755]
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[0771] [0772] [0773] [0774] [0775]
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[0793] [0794] [0795] [0796] [0797]
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[0815] [0816] [0817] [0818] [0819]
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[0838] [0839] [0840] [0841] [0842]
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[0868] [0869] [0870] [0871] [0872]
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[0893] [0894] [0895] [0896] [0897]
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[0917] [0918] [0919] [0920] [0921]
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[0944] [0945] [0946] [0947] [0948]
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[0976] [0977] [0978] [0979] [0980]
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[1033] [1034] [1035] [1036] [1037]
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[1091] [1092] [1093] [1094] [1095]
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[1152] [1153] [1154] [1155] [1156]
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[1210] [1211] [1212] [1213] [1214]
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[1271] [1272] [1273] [1274] [1275]
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[1331] [1332] [1333] [1334] [1335]
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[1391] [1392] [1393] [1394] [1395]
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[1452] [1453] [1454] [1455] [1456]
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[1514] [1515] [1516] [1517] [1518]
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[1575] [1576] [1577] [1578] [1579]
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[1635] [1636] [1637] [1638] [1639]
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[1695] [1696] [1697] [1698] [1699]
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[1756] [1757] [1758] [1759] [1760]
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[1817] [1818] [1819] [1820] [1821]
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[1877] [1878] [1879] [1880] [1881]
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[1937] [1938] [1939] [1940] [1941]
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[1997] [1998] [1999] [2000] [2001]
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[2059] [2060] [2061] [2062] [2063]
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[2121] [2122] [2123] [2124] [2125]
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[2177] [2178] [2179] [2180] [2181]
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[2249] [2250] [2251] [2252] [2253]
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[2378] [2379] [2380] [2381] [2382]
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[2418] [2419] [2420] [2421] 서열
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도면2 - 187 - 공개특허 10-201
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도면4 - 189 - 공개특허 10-201
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도면6 - 191 - 공개특허 10-201
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도면8 - 193 - 공개특허 10-201
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도면10a - 195 - 공개특허 10-2
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도면10c - 197 - 공개특허 10-2
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도면10e - 199 - 공개특허 10-2
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도면12 - 201 - 공개특허 10-20
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도면14 - 203 - 공개특허 10-20
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도면16 - 205 - 공개특허 10-20
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도면18 - 207 - 공개특허 10-20
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도면20 - 209 - 공개특허 10-20
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도면22 - 211 - 공개특허 10-20
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도면24 - 213 - 공개특허 10-20
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도면26a 도면26b - 215 - 공개
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도면28 - 217 - 공개특허 10-20
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도면30 도면31 - 219 - 공개특
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도면33 - 221 - 공개특허 10-20
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도면35 - 223 - 공개특허 10-20
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도면36b - 225 - 공개특허 10-2
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도면37b - 227 - 공개특허 10-2
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도면39 - 229 - 공개특허 10-20
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도면41 - 231 - 공개특허 10-20
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도면43 - 233 - 공개특허 10-20
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도면45 - 235 - 공개특허 10-20
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도면47 - 237 - 공개특허 10-20
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도면49 - 239 - 공개특허 10-20
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도면51 - 241 - 공개특허 10-20
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도면53 - 243 - 공개특허 10-20
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도면56 도면57 - 245 - 공개특
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도면60 도면61 - 247 - 공개특
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Smith, Jeffrey T.L. Schatzman, Rand
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Leu Pro Gly Ala Arg Cys Ala Tyr Asp
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PRT Oryctolagus cuniculus 6 Gln G
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agggcatcca ctctggcatc t 21 14 36
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99 PRT Oryctolagus cuniculus 20
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100 105 110 Val Arg Gly Gly Ala Val
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501 DNA Oryctolagus cuniculus 30
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85 90 95 Leu Thr Ile Thr Asp Val Gl
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1 5 43 16 PRT Oryctolagus cunic
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gtctactaca tgaac 15 51 48 DNA O
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145 150 155 160 Ala Leu Gly Cys Leu
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gagcagctga aggagtccgg aggaggcctg gt
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Val Val Val Lys Arg Thr Val Ala Ala
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75 Ile Ile Gly Gly Phe Gly Thr Thr
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Oryctolagus cuniculus 83 atcattggt
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tgggcgaaag gccgattcac catctccaaa ac
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145 150 155 160 Leu Asn Asn Phe 10
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108 12 PRT Oryctolagus cuniculus
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PRT Oryctolagus cuniculus 120 Ile
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125 Glu Ile Ser Lys Leu Glu Ser 1 5
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133 gaaatatcca aactggaatc t 21 134
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100 105 110 Val Arg Ser Leu Lys Tyr
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gcgaaaggcc gattcaccat ctccaagacc tc
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1 5 10 15 Val Gln Cys Gln Ser Val G
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gtcaccatca gttgccagtc cagtcagagt gt
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50 55 60 Gly Gln Arg Pro Lys Leu Le
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aattatggtg gtgatgaaag tttg 24 186
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Oryctolagus cuniculus 199 agcggcta
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213 21 DNA Oryctolagus cuniculus
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65 70 75 80 Ala Lys Gly Arg Phe Thr
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100 105 110 Leu Gly Ser Tyr Asp Cys
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Ala Tyr Asp Leu 1 242 375 DNA O
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Met Asp Thr Arg Ala Pro Thr Gln Leu
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1 5 256 16 PRT Oryctolagus cuni
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DNA Oryctolagus cuniculus 264 ttc
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Trp Ala Ser Thr Leu Ala Ser 1 5 27
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284 11 PRT 115 120 125 Oryctolag
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tacgcgagtt gggcgaaagg ccgattcacc at
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1 5 10 15 Val Gln Cys Gln Ser Val G
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aaaccagggc agcctcccaa gctcctgatc ta
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65 70 75 80 Gly Val Pro Ser Arg Phe
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gtcattggcg atactgctgg ttatgcttat tt
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1 5 10 < 210> 335 5 PRT Oryctola
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Oryctolagus cuniculus 348 Gln Ala
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Oryctolagus cuniculus 356 caggccag
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Ser Thr Tyr Tyr Ile Tyr Trp Val Arg
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gacctggagt gtgacgatgc tgccacttac ta
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Pro Ser Arg Phe Lys Gly Ser Gly Ser
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DNA Oryctolagus cuniculus 407 agc
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1 5 10 413 7 PRT Oryctolagus cu
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65 70 75 80 Ala Lys Gly Arg Phe Thr
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atggagactg ggctgcgctg gcttctcctg gt
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450 atggacacga gggcccccac tcagctgct
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Val Ser Ala Ala Val Gly Gly Thr Val
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Ile Ile Ala Asn Ser Gly Thr Thr Phe
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DNA Oryctolagus cuniculus 473 gag
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478 Gln Gln Gly Ala Thr Val Tyr Asp
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492 Gln Ala Ser Glu Asn Ile Tyr Ser
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500 caggccagtg agaacattta tagcttttt
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50 55 60 Trp Ile Gly Ile Ile Thr Gl
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Oryctolagus cuniculus 515 atggagac
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523 122 PRT 115 120 Oryctolagus
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DNA Oryctolagus cuniculus 530 atg
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20 25 30 Val Ser Val Pro Val Gly As
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Oryctolagus cuniculus 544 Phe Ile
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Oryctolagus cuniculus 558 Gln Gln
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Oryctolagus cuniculus 566 caacaggg
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PRT Oryctolagus cuniculus 572 Gln
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DNA Oryctolagus cuniculus 580 cag
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aacaggggag agtgt 315 588 330 PRT
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tacgtggacg gcgtggaggt gcataatgcc aa
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15 PRT Homo sapiens 598 Asp Lys
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Ser Lys Glu Ala Leu Ala Glu Asn Asn
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15 PRT Homo sapiens 617 Cys Leu
Page 429 and 430:
626 Glu Gln Ala Arg Ala Val Gln Met
Page 431 and 432: 15 PRT Homo sapiens 636 Asp Pro
Page 433 and 434: 645 Leu Arg Ser Phe Lys Glu Phe Leu
Page 435 and 436: PRT Homo sapiens 650 Asp Ile Gln
Page 437 and 438: 20 25 30 Tyr Met Ser Trp Val Arg Gl
Page 439 and 440: 65 70 75 80 Gln Met Asn Ser Leu Arg
Page 441 and 442: 122 PRT Oryctolagus cuniculus 66
Page 443 and 444: gcaaaattta acttg 375 664 450 PRT
Page 445 and 446: 450 665 450 PRT Oryctolagus cun
Page 447 and 448: Gly Lys 450 666 216 PRT Oryctol
Page 449 and 450: 20 25 30 Pro Gly Thr Pro Leu Thr Le
Page 451 and 452: 1 5 10 15 Val Gln Cys Gln Ser Leu G
Page 453 and 454: 676 Met Glu Thr Gly Leu Arg Trp Leu
Page 455 and 456: PRT Oryctolagus cuniculus 680 Met
Page 457 and 458: 684 128 PRT 115 120 Oryctolagus
Page 459 and 460: 100 105 110 Gly Tyr Ser Leu Arg Asn
Page 461 and 462: 85 90 95 Arg Asp Asp Ser Ser Asp Tr
Page 463 and 464: 85 90 95 Arg Asp Asp Ser Ser Asp Tr
Page 465 and 466: 85 90 95 Ile Asp Asn Ala Phe Gly Gl
Page 467 and 468: 50 55 60 Ser Gly Ser Gly Thr Asp Ph
Page 469 and 470: Lys Val Tyr Ala Cys Glu Val Thr His
Page 471 and 472: 195 200 205 Pro Ser Asn Thr Lys Val
Page 473 and 474: Leu Ile Tyr Arg Ala Ser Thr Leu Ala
Page 475 and 476: 50 55 60 Trp Val Gly Ile Ile Tyr Gl
Page 477 and 478: 35 40 45 Tyr Arg Ala Ser Thr Leu Al
Page 479 and 480: 212> PRT Homo sapiens 718 Val Ile
Page 481: ttcagcggca gtggatctgg gacagacttc ac
Page 485 and 486: 210 215 220 Thr Ala Val Ala Arg Asn
Page 487 and 488: 195 200 205 Ser Asp His Ile Asn Phe
Page 489: 690 695 700 Pro Glu Asp Leu Lys Ser
show all

(19) 대한민국특허청(KR) (12) 공개특허공보(A) - Questel

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