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2298 J. Med. Plants Res. and polyenes. Lancet Infect. Dis., 2: 550-563. Mosmann T (1983). Rapid colorimetric assay for cellular growth and survial: application to proliferation and cytotoxicity assays. J. Immunol. Methods, 65: 55-63. Pfaller MA (1995). Nosocomical candidiasis: Epidermiology of candidiasis. J. Hosp. Infect., 30: 329-338. Richardson MD, Kokki MH (1998). Diagnosis and prevention of fungal infection in the immunocompromized patient. Blood Rev., 12: 241- 244. Schaberg DR, Culver DH, Gaynes RP (1991). Major trends in the microbial etiology of nosocomial infection. Am. J. Med., 91: 72S-75S. Verduyn LFM, Meis JF, Voss A (1993). Nosocomial fungal infections: candidemia. Diagn. Microbiol. Infect. Dis., 34: 213-220. Williamson EM (2001). Synergy and other interactions in phytomedicines. Phytomedicine, 8: 401-409.
Journal of Medicinal Plants Research Vol. 6(12), pp. 2299-2308, 30 March, 2012 Available online at http://www.academicjournals.org/JMPR DOI: 10.5897/JMPR11-411 ISSN 1996-0875 ©2012 <strong>Academic</strong> <strong>Journals</strong> Full Length Research Paper Evaluation and comparison of antifungal activities of Terminalia catappa and Terminalia mantaly (Combretaceae) on the in vitro growth of Aspergillus fumigatus ZIRIHI Guédé Noël 1 *, N’GUESSAN Koffi 1 , KASSY N’dja Justin 1 , COULIBALY Kiyinlma 1,3 and DJAMAN Allico Joseph 2 1 University of Cocody-Abidjan, Unité de Formation et de Recherche (U.F.R.) Biosciences, Laboratoire de Botanique, 22 BP 582 Abidjan 22, Côte-d’Ivoire. 2 University of Cocody-Abidjan, Unité de Formation et de Recherche (U.F.R.) Biosciences, Laboratoire de Pharmacodynamie Biochimique, 22 BP 582 Abidjan 22, Côte-d’Ivoire. 3 Unité des Antibiotiques des Substances naturelles et de Surveillance de la Résistance des Micro-organismes aux Antiinfectieux, Institut Pasteur de Côte d’Ivoire, 01 BP 490 Abidjan 01, Côte-d’Ivoire. Accepted 21 December, 2011 Many surveys performed around the world have mentioned that among the plant species belonging to Combretaceae family, Terminalia catappa is the most requested medicinal plant. In recent decades, traditional healers in southern region of Côte d’Ivoire prefer to use the bark of Terminalia mantaly instead of those of T. catappa. The purpose of this study is to compare the pharmacological activities of these plants. The results of the anti-fungal activities of aqueous, hydroalcoholic and residual extracts on the growth of Aspergillus fumigates, a fungal pathogen, show that Terminalia mantaly water extract is 64 times more active than T. catappa water extract; hydroalcoholic extract of T. mantaly is 2 times more active than hydroalcoholic extract of T. catappa and residual extract of T. mantaly is 128 times more active than residual extract of T. catappa. Analysis of these results shows clearly that T. mantaly extracts are more active than extracts of T. catappa. The choice of T. mantaly and abandon of T. catappa by traditional healers in making medicines against skin infections is due to abundance of this plant in all areas and settlements and its excellent activities on many pathogens. Key words: Côte d’Ivoire, Terminalia catappa, Terminalia mantaly, antifungal activity. INTRODUCTION Ethnopharmacological surveys performed around the world have mentioned that among the plant species belonging to Combretaceae family, Terminalia catappa is the most requested medicinal plant (N’guessan, 2008). In Côte d’Ivoire, the roots bark decoction is used as antipyretic (Zirihi, 1991; N’guessan, 1995). In Nigeria, the decoction of leaves is used as medicine against malaria and abdominal pains (Amenoudji, 1990). In Togo and Benin root barks decoction is used in the treatment of *Corresponding author. E-mail: noel_zirihi @yahoo.fr. Tel: 0022548042873. various dermatosis (Amenoudji, 1990; Batawila et al., 2005; Baba-moussa, 1999; Baba-moussa et al., 1999). In Phillipines, leaves extract is used against leprosies (Burkill, 1997). In recent decades, traditional healers in southern region of Côte d’Ivoire prefer to use the bark of Terminalia mantaly instead of those of T. catappa (Zirihi, 1991). According to Coulibaly (Coulibaly, 2006), roots of T. catappa and leaves of Terminalia mantaly are used against the loss of voice. Indeed, unlike T. catappa, T. mantaly abounds in this part of Côte d’Ivoire, this plant is found along roads side, streets and even in the settlements (Aké-Assi, 1984). The purpose of this study is to compare the pharmacological activities of T. catappa a medicinal plant well known and well studied to those of
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Journal of Medicinal Plants Researc
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Editors Prof. Akah Peter Achunike E
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Electronic submission of manuscript
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Fees and Charges: Authors are requi
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Table of Contents: Volume 6 Number
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Figure 1. Chuanxiong Rhizoma (http:
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Table 1. Identification of main pea
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Table 3. Pharmacokinetic parameters
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Page 41 and 42: known fatty acids and terpenoids we
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Page 55 and 56: Table 3. Climatic and soil factors
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Page 61 and 62: Percentage inhibition % of inhibiti
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Page 97 and 98: ACKNOWLEDGMENTS The authors would l
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Page 101 and 102: Figure 3. The most widely included
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Page 105 and 106: Table 1. List of plants included in
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Table 1. Levels of independent vari
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Arbutin (mg/g) Co-solvent Figure 1.
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Arbutin (mg/g) Extraction pressure
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Table 3. Arbuitn content of Asian p
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Arbutin (mg/g) Extraction pressure
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Arbutin (mg/g) Extraction temperatu
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Table 1. Chemical composition of es
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Darjazi 2369 Table 2. Statistical a
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Table 3. Correlation matrix (number
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Table 1. Precision test. extraction
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Figure 2. Effect of different alcoh
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Table 6. Results of ANOVA. Nie et a
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Table 2. Plant data and MIC values
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exhibiting the polar extracts of P.
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Table 3. Contd. AcOEt ++ ++ ++ - Me
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Figure 1. Map of Ladakh region of I
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Warghat et al. 2391 Table 3. Summar
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Table 5. Inter-Population genetic i
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Excoffier L, Smouse PE, Quattro JM
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ice residue is an ideal raw materia
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DPPH• scavenging ratio(%) OD valu
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scavenging effect on free radical a
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our new CL system. Fenton reaction
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1 2 Time (s) Figure 2. Kinetic curv
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Wong et al., 2006). It can be seen
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Pan YM, Liang Y, Wang HS, Liang M (
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2422 J. Med. Plants Res. close cano
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2424 J. Med. Plants Res. Table 1. M
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2434 J. Med. Plants Res. Table 6. T
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2436 J. Med. Plants Res. budget dur
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2440 J. Med. Plants Res. Table 1. R
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2442 J. Med. Plants Res. Stability
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2444 J. Med. Plants Res. production
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2446 J. Med. Plants Res. Figure 2.
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2450 J. Med. Plants Res. Table 2. A
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2452 J. Med. Plants Res. Ghasemi Pi
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2460 J. Med. Plants Res. Department
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2466 J. Med. Plants Res. AOAC (2000
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2486 J. Med. Plants Res. components
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2490 J. Med. Plants Res. Inhibition
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2500 J. Med. Plants Res. Flowering
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2524 J. Med. Plants Res. ACKNOWLEDG
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UPCOMING CONFERENCES 15th European
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