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motivation should be taken into account, but neurobiological factors might also be veryimportant. Especially in this relatively new field of brain research and neurobiology, treatmentand research should progress in close cooperation. Furthermore, findings might be used inexperimental treatment conditions to help integrate and adapt research findings to clinicalpractice. The “what works” principles (Andrews et al. 1990) to determine the best treatment forcriminal behavior are based on social and psychological factors. Adding genetic andneurobiological factors, which will especially have an impact on the Responsivity Principle,would enrich this model.139. PsychopathyPsyochopathy, Between the Neurosciences and the Law: An Observational StudyF. Carabellese, University of Bari (felicefrancesco.carabellese@uniba.it)(f.carabellese.@criminologia.uniba.it)C. Benazzi, Psychiatric Hospital of Castiglione delle Stiviere, Italy (cristina.benazzi@aopoma.it)A. Calogero, Psychiatric Hospital of Castiglione delle Stiviere, Italy(antonino.calogero@aopoma.it)C. Candelli, University of Bari (chiaracandelli@gmail.com)L. Castelletti, Psychiatric Hospital of Castiglione delle Stiviere, Italy(luca.castelletti@aopoma.it)R. Catanesi, University of Bari (roberto.catanesi@uniba.it)F. Franconi, Psychiatric Hospital of Castiglione delle Stiviere, Italy(filippo.franconi@aopoma.it))I. Rossetto, Psychiatric Hospital of Castiglione delle Stiviere, Italy (ilaria.rossetto@aopoma.it)T. Sartori, Psychiatric Hospital of Castiglione delle Stiviere, Italy (tiziana.sartori@aopoma.it)In recent publications it has been hypothesized that persistent immoral behavior may be due todeficits in some zones of the so-called “moral circuit” (Glenn et al., 2009). We conducted anobservational descriptive study of a population interned in the “Ospedale Psichiatrico Giudiziariodi Castiglione delle Stiviere” (an Italian psychiatric hospital under the aegis of the ItalianMinistry of Justice established in the 1970s) in order to: a) individuate psychopathic subjects;and b) examine which legal and clinical variables are correlated with a psychopathic condition.All patients (65 subjects) diagnosed at the forensic psychiatry assessment as affected by aPersonality Disorder were examined, applying the Psychopathy Checklist-Revised (Hare, 1991).A diagnosis of psychopathy was made in 30.7% of the sample. In 85% of the psychopathic malesthe expert witness diagnosis had been that of an Antisocial personality, while in females aBorderline disorder was prevalent (78%). These data seem to be in agreement with the literature(Sprague et al., 2012), that stresses a widespread underestimation, in the risk assessment field, ofthe potential for violence and female psychopathy rates. Analysis of the legal variables328