Seattle University Collaborative Projects - International Academy of ...

consequences, e.g. punishment. Currently, while adult brain imaging studies find evidence forthis theory, support for this hypothesis in adolescents is limited to studies with peripheralneurobiological measures. Moreover, longitudinal studies are lacking. Therefore, an innovativelongitudinal imaging study in juveniles with early onset DBD was conducted in which brainfunction parameters reflecting specific aspects of fear, i.e. fear conditioning andreward/punishment anticipation, were related to patterns of persisting versus desisting (transient)antisocial behaviour. Participants (n=150) were drawn from a unique large cohort (n=256) ofdelinquent juveniles in the Netherlands, of whom many have previously been diagnosed withearly onset DBD. Data collection was finished in Summer 2012. As such, fresh data will bepresented from structural and functional MRI analyses that will be performed in 2012/2013.Ultimately, results should extend current knowledge about the underlying brain mechanismspredicting the early pathogenesis and persistence of antisocial behaviour in juveniles and therebystimulate the development of specific and effective treatment strategies.Longitudinal Studies on HPA and ANS Activity in Relation to the Developmentand Persistence of Antisocial Behavior in AdolescentsLucres Jansen, VU Medical Centre (L.nauta@debascule.com)The Hypothalamic-Pituitary-Adrenal (HPA) system and Autonomic Nervous System (ANS)have been frequently studied in relation to antisocial behavior. However, most studies to datehave been cross-sectional, with single measurements of HPA and ANS activity. Evenlongitudinal studies including HPA and ANS activity as a possible predictor for future antisocialbehavior usually have not included repeated measurements of HPA and ANS activity. However,the activity of both systems is not only controlled by genetic/innate factors, but is also influencedby environmental (stress) factors. HPA and ANS activity in mental disorders may thus besusceptible to change over time. Two longitudinal studies on the development and persistence ofantisocial behavior including repeated measurements of HPA or ANS activity in adolescencewill be presented. Also, the stability of HPA and ANS activity during adolescence will bediscussed from a more methodological point of view.16. Bosnian War and its Causalities: The Voices of ConcentrationCamp Prisoners, Refugees, and SurvivorsA Child’s Life in a Refugee Camp: A Survivor RemembersAldijana Alijagic (rubenboers@gmail.com)Ms. Alijagic, now 29, discusses mental health consequences of exposure to violence, trauma, andthe danger of daily life in a refugee camp. “The first time that the war came to my town, we46