Final Program

98 SUNDAY • MAY 15
P1562
P1563
P1564
Facilitator:
P1565
P1566
P1567
P1568
P1569
P1570
P1571
A78
Modulation of Airway Smooth Muscle Cell Functions Via
Isocitrate Dehydrogenase 2 and TET-Mediated
Hydroxymethylation/B.H.-Y. Yeung, T. Dao, J. Huang, S. An,
W.-Y. Tang, Baltimore, MD, p.A2461
Elevated Histone H3K27 Methylation Mediates Intrinsic
Hypercontractility in Human Airway Smooth Muscle Cells from
Fatal Asthma Subjects/E. Yoo, J. Vivieros, S. Sidoli, G. Cao, B.A.
Garcia, R.A. Panettieri, Philadelphia, PA, p.A2462
Inhibition of Oxidized Phosphatidylcholine Formation in the
Lung of Allergen-Challenged Mice: Comparison of Effects for
Inhaled Simvastatin and Corticosteroid Treatment/A. Jha, M.H.
Ryu, C.D. Pascoe, R. Chaudhary, A. Ravandi, A.J. Halayko,
Winnipeg, Canada, p.A2463
T. Tran, PhD, Singapore, Singapore
MicroRNA-155 Targets Tristetraprolin and Enhances Cytokine
Expression in Airway Smooth Muscle/B.S. Comer, A.J. Halayko,
W. Gerthoffer, Indianapolis, IN, p.A2464
microRNA-25 Targets TSC1 and KLF4 to Regulate ASM
Phenotype/M. Ba, M. Hernandez, J. Evasovic, C.A. Singer, Reno,
NV, p.A2465
Enhanced a7-Integrin Expression Inhibits miR-124a
Expression and Supports a Contractile Phenotype in Airway
Smooth Muscle/L. Schultz, J. Evasovic, P. Cay, A. Aiyuk, S.
Romanick, M. Ba, R. Wuebbles, D. Burkin, N. Leblanc, C.A. Singer,
Reno, NV, p.A2466
Effects of Roflumilast and Albuterol on Airway
Hyperresponsiveness (AHR) Induced by IL-13/R.G. Townley, S.
Agrawal, M.R. Hanna, P.J. Oldenburg, Omaha, NE, p.A2467
Scaffolding Protein A-Kinase Anchoring Protein 12 Enhances
b2-Adrenoceptor Sensitivity in Tracheal Smooth Muscle/
M. Schmidt, W.J. Poppinga, C. Elzinga, H. Meurs, H. Maarsingh,
Groningen, Netherlands, p.A2468
Airway Responsiveness and Inflammation Is Regulated by p21
Activated Kinase (Pak)1 in Airway Smooth Muscle (ASM) in a
Murine Model of Asthma/W. Zhang, H. Gao, Q. Yu, R.S. Tepper,
S.J. Gunst, Indianapolis, IN, p.A2469
Multiwalled Carbon Nanotubes Inhibit Migration of Airway
Smooth Muscle Cells/L. Deng, M. Luo, Z. Sun, Y. Lu, Y. Wang, L.
Liu, Changzhou, China, p.A2470
THEMATIC POSTER SESSION
AIRWAY SMOOTH MUSCLE: WHAT’S UNDER THE
HOOD?
9:00 a.m. - 4:15 p.m. MOSCONE CENTER
Viewing: Posters will be on display for entire session.
Area N, Hall D (North Building, Lower Level)
Discussion: 11:00-11:45: authors will be present for individual discussion
11:45-12:45: authors will be present for discussion with assigned facilitators
Facilitator:
P1573
P1574
P1575
P1576
P1577
P1578
P1579
Facilitator:
P1580
P1581
P1582
P1583
P1584
P1585
P1586
C.Y. Seow, PhD, Vancouver, Canada
Distinct Airway Nerve Subtypes Mediate a Toll-Like Receptor
7-Dependent Bronchodilation/M.G. Drake, B. Proskocil, E. Blum,
K. Lebold, A.D. Fryer, D.B. Jacoby, Portland, OR, p.A2471
Structural Insights into the Serotonin- and Muscarinic-Induced
Smooth Muscle Constriction of Murine Caveolin-3 in
Airways/M. Keshavarz, M. Skill, U. Pfeil, M. Walecki, W. Kummer,
G. Krasteva-Christ, Giessen, Germany, p.A2472
An Assessment of Ca2+ Sensitivity of Intact Airway Smooth
Muscle Contraction Using Phase Loop Plots/Y.-S. Han, M.
Dogan, P. Delmotte, G.C. Sieck, Rochester, MN, p.A2473
A Comparison of Airway Contractility and Ca2+ Oscillations in
Airway Smooth Muscle in Precision-Cut Lung Slices from
BALB/c and C57BL/6 Mice/J. Chen, M.J. Sanderson, Worcester,
MA, p.A2474
High CO2 Induces Airway Smooth Muscle Contraction Via
Inhibition of Micro RNA 133a/M. Shigemura, E. Lecuona, M.
Angulo, E. Ceco, L.C. Welch, J.I. Sznajder, Chicago, IL, p.A2475
Necroptosis Signalling in Lung Epithelial Cells Modulates
Mitochondrial Function and Reactive Oxygen Species
Generation in Healthy and Asthmatic Airway Smooth Muscle
(ASM) Cells/O.O. Ojo, C. Wiegman, K.F. Chung, I.M. Adcock,
London, United Kingdom, p.A2476
Airway Hyperresponsiveness Is Associated with Peripheral
Airway Smooth Muscle Hypercontractility in the Horse Model
of Severe Asthma/O. Matusovsky, L. Kachmar, G. Ijpma, N.
Zitouni, G. Bates, J.-P. Lavoie, A.-M. Lauzon, Montreal, Canada,
p.A2477
H. Parameswaran, PhD, Boston, MA
Elution of Contractile and Cytoskeletal Proteins from Skinned
Airway Smooth Muscle/L. Wang, C.Y. Yu, P.D. Pare, C.Y. Seow,
Vancouver, Canada, p.A2478
Time Course of Incorporation of Myosin Molecules into the
Contractile Units of Smooth Muscle/L. Wang, C. Labonte
Raymond, P.D. Pare, C.Y. Seow, Vancouver, Canada, p.A2479
The Influence of Interleukin-13 on Airway Smooth Muscle
Tissue Mechanics/N.E. Swyngedouw, L. Wang, P.D. Pare, C.Y.
Seow, Vancouver, Canada, p.A2480
Nicotine-Induced Airway Hyperresponsiveness May Be Due to
Inappropriate Lynx1 Levels in Airway Smooth Muscle Cells/C.
Wongtrakool, D. Jia, K. Grooms, M. Hart, Decatur, GA, p.A2481
Airway Smooth Muscle Cell Mechanical Force Characterization
from In-Utero to Elderly/R.M. Buchmann, M. Freeman, L.J.
Manlove, I. Kuipers, A.J. Haak, V. Sathish, M.A. Thompson, D.J.
Tschumperlin, C. Pabelick, Y.S. Prakash, Milwaukee, WI, p.A2482
Airway Smooth Muscle Cell Size Increases with Age in Healthy
Individuals/J. Elliot, R. Jones, N. Sandosham, S.-A. Drew, K.
McKay, P. Noble, A. James, Nedlands, Australia, p.A2483
Collapsibility of Ovine Bronchi Decreases Throughout Life Due
to the Emergence of Basal Smooth Muscle Tone/A.Y.-H. Chang,
N. Sorensen, S. Ahmadi-Noorbakhsh, J.J. Pillow, P.B. Noble,
Perth, Australia, p.A2484
ATS 2016 • San Francisco