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396 WEDNESDAY • MAY 18<br />

1:30 The Biology of Acute Exacerbations of COPD<br />

P.J. Barnes, MD, DSc, London, United Kingdom<br />

1:45 The Physiology of Acute Exacerbations of COPD<br />

B.R. Celli, MD, Boston, MA<br />

2:00 Role of the Eosinophil in COPD Exacerbations<br />

C.E. Brightling, BSc, MBBS, PhD, Leicester, United Kingdom<br />

2:15 Kinases and PDE-4 Inhibitors and COPD Exacerbations<br />

F.J. Martinez, MD, New York, NY<br />

2:30 Antioxidant Therapy to Prevent COPD Exacerbations<br />

R.A. Wise, MD, Baltimore, MD<br />

2:45 Potential Role of Anti-Fibrotic Therapy in COPD<br />

G.J. Criner, MD, Philadelphia, PA<br />

3:00 Stimulating Lung Repair Following Acute Exacerbations<br />

S.I. Rennard, MD, Melbourn, United Kingdom<br />

3:15 Targeting the Neutrophil in COPD Exacerbations<br />

H. Magnussen, MD, PhD, Grosshansdorf, Germany<br />

This session and the International Conference are supported by an educational grant from<br />

AstraZeneca LP.<br />

All CME sessions have been planned and implemented in accordance with the Essential<br />

Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME)<br />

and are free of the control of commercial interests.<br />

D84<br />

CLINICAL<br />

CRITICAL CARE TRACK<br />

CME Credits Available: 2.0<br />

STAY AWAY FROM THE ICU: IS PREVENTING ICU<br />

ADMISSION GOOD FOR PATIENTS?<br />

Assembly on Critical Care<br />

1:30 p.m. - 3:30 p.m. MOSCONE CENTER<br />

Room 3000/3002/3004 (West Building, Level 3)<br />

Target Audience<br />

Critical care and emergency medicine professionals; anesthesia clinicians,<br />

including physicians, nurses, and advanced practice providers.<br />

Objectives<br />

At the conclusion of this session, the participant will be able to:<br />

• learn new data on how to identify patients at risk for clinical deterioration;<br />

• better discuss the risks and benefits of ICU admission with patients and<br />

their families;<br />

• better identify patients that will not benefit from ICU admission.<br />

ICU beds and the nurses and physicians that staff them remain a scarce and<br />

costly resource. In addition, admission to an ICU is associated with both<br />

increased intensity of therapy, but also potential increased risks of treatment.<br />

One way to deal with the limitations of bed space as well as the increased risk<br />

of ICU care is to attempt to identify and treat patients at risk for critical illness<br />

earlier in their illness. This session will review available data on identification of<br />

and treatment for patients on the wards and in the prehospital phase, and<br />

whether this will prevent need for ICU admission<br />

Chairing: J.E. Sevransky, MD, MHS, Atlanta, GA<br />

C.R. Cooke, MD, MSc, Ann Arbor, MI<br />

K.S. Mathews, MD, MPH, New York, NY<br />

1:30 Risks and Benefits of ICU Admission<br />

C.R. Cooke, MD, MSc, Ann Arbor, MI<br />

1:50 Can Patients with Severe Sepsis Be Safely Treated on the<br />

Wards?<br />

M.E. Mikkelsen, MD, Philadelphia, PA<br />

2:10 Prehosptial Identification of Severe Sepsis Patients<br />

C. Polito, MD, MSc, Atlanta, GA<br />

2:30 Early Warning Systems to Predict Clinical Deterioration: Do<br />

They Work?<br />

M.M. Churpek, MD, MPH, PhD, Chicago, IL<br />

2:50 Should Palliative Care Consultation Be Used to Prevent ICU<br />

Admissions?<br />

N. Khandelwal, MD, Seattle, WA<br />

3:10 Prevention of Lung Injury<br />

E. Festic, MD MS, Jacksonville, FL<br />

D85<br />

BASIC • BEHAVIORAL • CLINICAL • TRANSLATIONAL<br />

SCIENTIFIC SYMPOSIUM<br />

CME Credits Available: 2.0<br />

EARLY LIFE ORIGINS OF CHRONIC DISEASE<br />

Assemblies on Pediatrics; Clinical Problems; Environmental,<br />

Occupational and Population Health; Pulmonary Rehabilitation;<br />

International Health Committee<br />

1:30 p.m. - 3:30 p.m. MOSCONE CENTER<br />

Room 2016/2018 (West Building, Level 2)<br />

Target Audience<br />

Providers of lung health; trainees; fellows; junior faculty; research scientists;<br />

clinical academics.<br />

Objectives<br />

At the conclusion of this session, the participant will be able to:<br />

• learn new findings about early life origins of chronic disease;<br />

• gain and apply new knowledge gained to thinking about disease causation;<br />

• understand how early life exposures can increase life long disease risk.<br />

Globally chronic disease is increasing in both developed and developing<br />

countries. Evidence is increasing that most chronic disease has it origin in early<br />

life, that is during the peri-conceptual period, during fetal development and in<br />

early postnatal life. This session will highlight current thinking in how early life<br />

exposures result in chronic disease in later life.<br />

Chairing: M. Rosenfeld, MD, MPH, Seattle, WA<br />

J.C. Celedon, MD, DrPH, Pittsburgh, PA<br />

1:30 Developmental Origins of Health and Disease: The DOHAD<br />

Studies<br />

M. Hanson, MA, DPhil, Southampton, United Kingdom<br />

1:55 Impact of Prenatal and Early Life Exposures on Development<br />

T. Bastain, PhD, MPH, Los Angeles, CA<br />

ATS 2016 • San Francisco

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