402 WEDNESDAY • MAY 18 D96 MINI SYMPOSIUM DAMAGING EFFECTS OF INHALED PARTICULATES 1:30 p.m. - 3:30 p.m. MOSCONE CENTER Chairing: Oral Presentations Room 2006/2008 (West Building, Level 2) 1:30 Acute Exposure to Electronic Cigarettes in Healthy Nonsmokers Leads to Global Transcriptome Changes in Distal Airway Epithelium and Alveolar Macrophages/M.R. Staudt, J. Salit, A.E. Tilley, R.J. Kaner, F. Agosto-Perez, C. Hollmann, R.G. Crystal, New York, NY, p.A7512 1:45 MTOR Suppresses Cigarette Smoke-Induced Airway Inflammation and Emphysema/J.S. Zhou, J. Liu, Y. Wang, Z.Y. Li, S.M. Ying, W. Li, H.H. Shen, Z.H. Chen, Hang Zhou, China, p.A7513 2:00 Ergothioneine Protects Lung Epithelial Cells from Tobacco Smoke-Induced Oxidative Damage In Vitro and In Vivo/S. Nickel, M. Selo, C. Clerkin, B. Talbot, J. Walsh, N. Nakamichi, Y. Kato, P. Reynolds, J. Lewis, C. Ehrhardt, Dublin, Ireland, p.A7514 2:15 MKK3 Mediates Inflammatory Response and Mitochondrial Dysfunction After Cigarette Smoke Injury/A. Srivastava, S. Erramilli, P.J. Lee, P. Mannam, New Haven, CT, p.A7515 2:30 Macrophage Migration Inhibitory Factor (MIF) Accelerates DNA Repair Via Its Receptor CD74 in a Novel In-Vitro Model of Cigarette Smoke Mediated Endothelial Dysfunction/T. Baker, M. Haslip, L. Leng, R. Bucala, P.J. Lee, M. Sauler, New Haven, CT, p.A7516 2:45 RAGE Contributes to Particulate-Induced Lung Function Loss and Hyperreactivity: Mitigating the Persistent Effects of a Single Intense Particulate Exposure/S. Kwon, S.H. Haider, E.J. Caraher, G. Crowley, A.K. Lee, M. Ebrahim, D.J. Prezant, A.M. Schmidt, A. Nolan, New York, NY, p.A7517 3:00 Metformin Attenuates Particulate Matter Air Pollution Induced Thrombosis by Inhibiting Mitochondrial ROS Upstream of CRAC Channels in Alveolar Macrophages/S. Soberanes, A. Jairaman, M. Chi, A.Y. Meliton, J. Cho, F.J. Gonzalez-Gonzalez, A.C. Mc Quattie-Pimentel, R. Piseaux, S. Weinberg, H.R. Perlman, N.S. Chandel, A.V. Misharin, M. Prakriya, G.M. Mutlu, G.S. Budinger, Chicago, IL, p.A7518 3:15 Inhibition Of EGF Receptor Signaling Decreases Agricultural Dust-Mediated Lung Inflammatory Responses In Vivo and In Vitro/D.J. Romberger, T.M. Nordgren, A.J. Heires, N.A. Schulte, M.L. Toews, Omaha, NE, p.A7519 D97 MINI SYMPOSIUM IMAGING AND MODELING: INSIGHTS INTO LUNG STRUCTURE AND FUNCTION 1:30 p.m. - 3:30 p.m. MOSCONE CENTER Room 2002/2004 (West Building, Level 2) Chairing: K.R. Lutchen, PhD, Boston, MA C.C. Hsia, MD, Dallas, TX M.H. Tawhai, PhD, Auckland, New Zealand Oral Presentations 1:30 Postnatal Development of Pulmonary AciniA in Rats/T.P. Cremona, D. Haberthur, E. Yao, S. Barre, M. Stampanoni, J.C. Schittny, Bern, Switzerland, p.A7520 1:45 Deposited Particle Concentrations in Infant, Child, and Adult Image-Based Computational Fluid Dynamics (CFD) Models/J.M. Oakes, S.C. Roth, I.E. Vignon-Clementel, S.C. Shadden, Berkeley, CA, p.A7521 2:00 Imaging a Single Slice Provides a Representative Measure of Specific Ventilation in a Normal Lung: A Computational Modeling Study/K.S. Burrowes, W. Kang, G.K. Prisk, M. Tawhai, Oxford, United Kingdom, p.A7522 2:15 Comparison of Regional Ventilation and Lung Deformation for Asthmatic Vs. Healthy Human Lungs Using 4D-CT Image Data/N. Jahani, S. Choi, J. Choi, E.A. Hoffman, A.P. Comellas, J.N. Kline, C.-L. Lin, Iowa City, IA, p.A7523 2:30 Regional Increase in Airway Wall Thickness Could Explain Increase in Ventilation Defects (VDefs) and Heterogeneity in Ventilation in Asthma/T. Winkler, C. Thamrin, C.S. Farah, G.G. King, Boston, MA, p.A7524 2:45 Biomechanical Model of Inflammation-Induced Airway Smooth Muscle Mass Accumulation and Extracellular Matrix Deposition in an Ovalbumin Murine Model of Asthma/M.R. Hill, A.L. Tatler, R.D. O’Dea, C.K. Billington, A.E. John, K. Deacon, S.R. Johnson, B.S. Brook, Nottingham, United Kingdom, p.A7525 3:00 Novel Biomarkers of Lung Parenchyma Destruction and Emphysema Progression in COPD Using Inhaled Gas MRI Morphometry/E. Lessard, A. Ouriadov, D.P. Capaldi, D.G. McCormack, G. Parraga, London, Canada, p.A7526 3:15 Automated Quantitative Evaluation of Alveolar Structure on Confocal Laser Endomicroscopy/D. Bondesson, T. Gaass, J. Behr, F. Reichenberger, J. Dinkel, E. Silbernagel, Munich, Germany, p.A7527 D98 MINI SYMPOSIUM AFTER SERVE-HF: NOW WHAT? 1:30 p.m. - 3:30 p.m. MOSCONE CENTER Chairing: S. Javaheri, MD, Cincinnati, OH M. Arzt, MD, Regensburg, Germany M. D’Ortho, MD, PhD, Creteil, France Oral Presentations Room 2001/2003 (West Building, Level 2) 1:30 Morbidity and Mortality of Chronic Heart Failure (CHF) Patients Treated by Adaptative Servo-Ventilation (ASV): Interim Data of the FACE Multicentre National Cohort Study/R. Tamisier, T. Damy, J.-M. Davy, P. Levy, F. Goutorbe, L. Morin, J.L. Pepin, M.-P. D’Ortho, Grenoble, France, p.A7528 ATS 2016 • San Francisco
WEDNESDAY • MAY 18 403 1:45 Obstructive and Central Sleep Apnea Are Associated with Increased CaMKII-Dependent Sarcoplasmic Reticulum Calcium Leak in Human Atrial Cardiomyocytes/S. Ripfel, M.A. Drzymalski, S. Meindl, A. Biedermann, M. Durczok, T. Islam, S. Katz, M. Mendl, T. Weizenegger, B. Florchinger, D. Camboni, S. Wittmann, J. Backs, C. Schmid, L.S. Maier, S. Wagner, M. Arzt, Regensburg, Germany, p.A7529 2:00 Adaptive Servo-Ventilation for Central Sleep Apnea in Systolic Heart Failure Does not Improve Muscle Sympathetic Nerve Activity: A SERVE-HF Substudy/R. Tamisier, J.L. Pepin, M. Salvat, H. Woehrle, G. Barone-Rochette, C. Rocca, H. Teschler, M. Cowie, P. Levy, Grenoble, France, p.A7530 2:15 Dissociation of Objective and Subjective Daytime Sleepiness Measures in Patients with Heart Failure and Obstructive Sleep Apnea/S. Javaheri, R. Mehra, N. Foldvary-Schaefer, Cincinnati, OH, p.A7531 2:30 Protective Cardiovascular Effect of Sleep Apnea Severity in Obesity Hypoventilation Syndrome/J.F. Masa, M.-A. Sanchez-Quiroga, J. Corral, A. Romero, C. Caballero, J. Teran-Santos, M.L. Alonso-Alvarez, T. Gomez-Garcia, M. Gonzalez, S. Lopez-Martinez, P. De Lucas, J.M. Marin, S. Marti, T. Diaz-Cambriles, E. Chiner, E. Miranda, C. Egea, A. Obeso, B. Mokhlesi,Caceres, Spain p.A7532 2:45 Associations Between Sleep Disordered Breathing and Subclinical Carotid Atherosclerosis: The Multi-Ethnic Study of Atherosclerosis/Y.Y. Zhao, R. Wang, S. Javaheri, B. Koo, C.E. Korcarz, J.H. Stein, S. Redline, Boston, MA, p.A7533 3:00 Long-Term Effect of CPAP on Subclinical Atherosclerosis in Obstructive Sleep Apnea/J.M. Marin, T. Martin, V. Gil, P. Cubero, M. Forner, A.L. Simon, Zaragoza, Spain, p.A7534 Featured Speaker 3:15 Carotid Body Targeting in Cardiovascular Disease: Taming the Roar/J. Paton, PhD, Bristol, United Kingdom, D99 MINI SYMPOSIUM NOVEL TRANSLATIONAL BIOMARKERS IN LUNG CANCER 1:30 p.m. - 3:30 p.m. MOSCONE CENTER Chairing: P. Nana-Sinkam, MD, Columbus, OH S.D. Spivack, MD, MPH, Bronx, NY Featured Speaker Room 306/308 (South Building, Esplanade Level) 1:30 Why Do We Need Biomarkers for Lung Cancer?/A. Vachani, MD, MS, Philadelphia, PA, Oral Presentations 1:45 Nasal Epithelial Gene Expression Is Altered in Patients with Lung Cancer and Reflects the Cancer-Associated Gene Expression Changes Observed in the Bronchial Epithelium/J. Perez-Rogers, J. Gerrein, C. Anderlind, G. Liu, S. Zhang, Y. Alekseyev, K. Porta, D. Whitney, A. Spira, M. Lenburg, Boston, MA, p.A7535 2:00 Chemoprevention with Myo-Inositol Alters Gene-Expression in the Airway Epithelium of Smokers with Dysplasia/Y.B. Gesthalter, M. Lenburg, P.J. Limburg, S.J. Mandrekar, S. Lam, K. Fursa, S.F. Kaufman, D. Seisler, E. Szabo, A. Spira, J. Beane, Boston, MA, p.A7536 2:15 Discovery and Validation of a Combined Serum Protein and Auto-Antibody Test for the Identification of Lung Cancer in a High Risk Population/P.J. Mazzone, X.-F. Wang, H. Choi, M. Seeley, V. Doseeva, R. Scherer, V. Knezevic, Cleveland, OH, p.A7537 2:30 Plasma TIMP-1 Identifies Lung Cancer in Smokers/V.S. Nair, H. Yu, A. Juang, A. Hattori, M. Ito, J. Rosenberg, G. Horng, W. Kuschner, S.M. Hanash, M. Beggs, L. Carbonell, S.X. Wang, Stanford, CA, p.A7538 2:45 Telomere Shortening in COPD and Lung Cancer: A Pilot Study in Chronic Smokers/R.P. Young, W. Whitford, R.J. Hopkins, Auckland, New Zealand, p.A7539 3:00 Immunoproteasome Deficiency in Non-Small Cell Lung Cancer Is Associated with Mesenchymal Phenotype, Restricted Antigen Presentation, and Poor Outcome/E.J. Ostrin, S. Tripathi, H.L. Peters, A. Taguchi, M.J. Schliekelman, H. Katayama, H. Wang, A. Momin, M. Celiktas, J. Rodriguez Canales, H. Liu, C. Behrens, I.I. Wistuba, J.J. Molldrem, S.M. Hanash, Houston, TX, p.A7540 3:15 Next Generation Sequencing of Solid Tumor and Circulating Tumor DNA (ctDNA) for Real-Time Monitoring of Metastatic Non-Small Cell Lung Cancer/J. Thompson, C. Langer, C. Aggarwal, J. Bauml, E. Carpenter, A. Vachani, Philadelphia, PA, p.A7541 D101 POSTER DISCUSSION SESSION ALLERGY AND ASTHMA: NOVEL REGULATORY PATHWAYS 1:30 p.m. - 3:30 p.m. MOSCONE CENTER Room 2024 (West Building, Level 2) Poster Viewing 1:30-2:15 Discussion 2:15-3:30 Chairing: M. Kraft, MD, Tucson, AZ J.L. Cho, MD, Boston, MA C. Donovan, BSc (Hons), Parkville, Australia 601 Identification of Transcriptional Regulators Controlling IL-17A-Mediated Enhancement of IL-13 Activity/S.L. Hall, I. Lewkowich, Cincinnati, OH, p.A7542 602 The Purinergic Receptor P2X4 Mediates Acute Airway Inflammation by Regulating Dendritic Cell Function/B. Wiesler, A. Zech, M. Idzko, Freiburg, Germany, p.A7543 603 P2Y14 Receptor Deficiency Attenuates Phenotype of Allergic Airway Inflammation in Mice/T. Schlaich, A. Zech, B. Wiesler, M. Hobfeld, M. Idzko, Freiburg, Germany, p.A7544 ATS 2016 • San Francisco WEDNESDAY AFTERNOON
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American Thoracic Society Internati
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TABLE OF CONTENTS ATS 2016 INTERNAT
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2 FRIDAY • MAY 13 PG2A CLINICAL P
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4 FRIDAY • MAY 13 Target Audience
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6 FRIDAY • MAY 13 11:15 Case Disc
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8 FRIDAY • MAY 13 Chairing: H.B.
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10 FRIDAY • MAY 13 10:25 Advanced
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12 FRIDAY • MAY 13 Objectives At
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14 SATURDAY • MAY 14 Abdominal Ul
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16 SATURDAY • MAY 14 PG17 BASIC
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18 SATURDAY • MAY 14 1:05 In What
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20 SATURDAY • MAY 14 10:30 Practi
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22 SATURDAY • MAY 14 Objectives A
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24 SATURDAY • MAY 14 10:10 Is My
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26 SUNDAY • MAY 15 Chairing: D.M.
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28 SUNDAY • MAY 15 Chronic Cough:
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30 SUNDAY • MAY 15 • understand
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32 SUNDAY • MAY 15 Target Audienc
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34 SUNDAY • MAY 15 Oral Presentat
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36 SUNDAY • MAY 15 9:15 Hyperpola
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38 SUNDAY • MAY 15 310 A Smartpho
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40 SUNDAY • MAY 15 103 Immunosupp
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42 SUNDAY • MAY 15 A26 POSTER DIS
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44 SUNDAY • MAY 15 822 Incidence
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46 SUNDAY • MAY 15 519 Maternal H
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48 SUNDAY • MAY 15 P14 P15 P16 P1
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104 SUNDAY • MAY 15 11:00 a.m.-12
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106 SUNDAY • MAY 15 L1 U.S. FOOD
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108 SUNDAY • MAY 15 12:15 Post-Pr
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110 SUNDAY • MAY 15 MP406 MP407 M
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112 SUNDAY • MAY 15 clinician and
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114 SUNDAY • MAY 15 A86 BASIC •
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116 SUNDAY • MAY 15 Chairing: M.J
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118 SUNDAY • MAY 15 3:30 High Pre
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120 SUNDAY • MAY 15 102 Toll-Like
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122 SUNDAY • MAY 15 A103 POSTER D
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124 SUNDAY • MAY 15 719 Lactate R
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126 SUNDAY • MAY 15 1014 Determin
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128 SUNDAY • MAY 15 611 Plasma Mi
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130 SUNDAY • MAY 15 412 Daytime S
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132 SUNDAY • MAY 15 6:30 p.m. - 8
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134 MONDAY • MAY 16 SS111 SS112 S
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136 MONDAY • MAY 16 Target Audien
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138 MONDAY • MAY 16 9:40 Empoweri
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140 MONDAY • MAY 16 9:28 Endotoxi
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142 MONDAY • MAY 16 10:15 Adaptiv
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144 MONDAY • MAY 16 Oral Presenta
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146 MONDAY • MAY 16 624 Neonatal
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148 MONDAY • MAY 16 118 Compariso
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150 MONDAY • MAY 16 912 Should Pa
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152 MONDAY • MAY 16 1015 Resverat
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154 MONDAY • MAY 16 718 Health Re
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156 MONDAY • MAY 16 P152 Facilita
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158 MONDAY • MAY 16 B35 THEMATIC
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160 MONDAY • MAY 16 P252 P253 P25
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164 MONDAY • MAY 16 P320 Bilatera
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172 MONDAY • MAY 16 B44 THEMATIC
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210 MONDAY • MAY 16 encourage tra
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212 MONDAY • MAY 16 B82 BEHAVIORA
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214 MONDAY • MAY 16 B86 BASIC •
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216 MONDAY • MAY 16 and a number
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218 MONDAY • MAY 16 2:30 Mortalit
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220 MONDAY • MAY 16 3:00 Simultan
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222 MONDAY • MAY 16 525 Clinical
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224 MONDAY • MAY 16 320 Sensitivi
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226 MONDAY • MAY 16 113 COPD Subt
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228 MONDAY • MAY 16 1004 Health C
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230 MONDAY • MAY 16 609 Skeletal
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232 MONDAY • MAY 16 5:00 p.m. - 7
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234 TUESDAY • MAY 17 Chairing: D.
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236 TUESDAY • MAY 17 CLINICAL YEA
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238 TUESDAY • MAY 17 This session
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240 TUESDAY • MAY 17 bronchiectas
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242 TUESDAY • MAY 17 Target Audie
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244 TUESDAY • MAY 17 C18 MINI SYM
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246 TUESDAY • MAY 17 415 Investig
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248 TUESDAY • MAY 17 207 Survival
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250 TUESDAY • MAY 17 906 Phenotyp
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252 TUESDAY • MAY 17 807 The Vali
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254 TUESDAY • MAY 17 515 Roles of
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312 TUESDAY • MAY 17 • become a
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328 TUESDAY • MAY 17 710 Follista
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330 TUESDAY • MAY 17 509 A Mechan
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332 TUESDAY • MAY 17 806 Upper Ai
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334 WEDNESDAY • MAY 18 6:45 Acute
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336 WEDNESDAY • MAY 18 CLINICAL Y
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338 WEDNESDAY • MAY 18 Objectives
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340 WEDNESDAY • MAY 18 D9 BASIC
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342 WEDNESDAY • MAY 18 Oral Prese
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344 WEDNESDAY • MAY 18 10:15 Plas
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346 WEDNESDAY • MAY 18 419 A Nove
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348 WEDNESDAY • MAY 18 216 Simpli
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350 WEDNESDAY • MAY 18 815 Multip
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