Final Program

WEDNESDAY • MAY 18 343
9:15 Safety and Tolerability of Intravenous Bone Marrow-Derived
Human Mesenchymal Stem Cells for Patients with Idiopathic
Pulmonary Fibrosis- The AETHER Study (NCT 2013700)/
R.L. Toonkel, P. Bejarano, D.L. DiFede, S.J. Elliot, J.E. Fishman,
J.M. Hare, A. Khan, V. LaRussa, Y.N. Mageto, A. Mendizabal, M.
Mushtaq, M.V. Pujol, G.A. Rubio, E. Simonet, S. Shafazand, M.
Glassberg, Miami, FL, p.A6433
9:30 N-Acetylcysteine Response Among Anti-Nuclear Antibody
Seropositive Patients with Idiopathic Pulmonary Fibrosis/J.M.
Oldham, C. Lee, E. Valenzi, L.J. Witt, A. Adegunsoye, L.W. Chen,
S. Hsu, S. Montner, J.H. Chung, R. Vij, M.E. Strek, I. Noth,
Chicago, IL, p.A6434
9:45 Impact of Statins on Lung Function Decline in Idiopathic
Pulmonary Fibrosis (IPF)/M. Kreuter, F. Bonella, T.M. Maher, U.
Costabel, P. Spagnolo, D. Weycker, K.-U. Kirchgassler, M. Kolb,
Heidelberg, Germany, p.A6435
10:00 Azathioprine for Antisynthetase-Associated Interstitial Lung
Disease/L.L. Silhan, J.A. Huapaya, S.K. Danoff, Baltimore, MD,
p.A6436
10:15 Functional Improvement in Patients with
Lymphangioleiomyomatosis (LAM) After Sirolimus/K.-F. Xu, Y.
Zhan, X. Tian, J. Wang, W. Xu, H. Cui, X. Li, Beijing, China,
p.A6437
10:30 Whole Lung Lavage Followed by Inhaled Sargramostim as
Therapy of Autoimmune Pulmonary Alveolar Proteinosis/I.
Campo, F. Mariani, E. Paracchini, Z. Kadija, M. Zorzetto, C. Tinelli,
G. Rodi, F. Meloni, M. Griese, B.C. Trapnell, G. Scheuch, B.
Muellinger, M. Luisetti, Pavia, Italy, p.A6438
D16
MINI SYMPOSIUM
CRITICAL CARE: REDUCING VARIATION IN USUAL
CARE
9:00 a.m. - 11:00 a.m. MOSCONE CENTER
Chairing: G.D. Rubenfeld, MD, MSc, Toronto, Canada
H.B. Gershengorn, MD, Bronx, NY
A.J. Walkey, MD, MSc, Boston, MA
Oral Presentations
Room 3003/3005 (West Building, Level 3)
9:00 Out of Sight: Lack of Geographic Co-Localization of Intensive
Care Unit Patients and Care Teams Is Associated with
Increased Mortality/R. Stretch, N. Della Penna, L.A. Celi, Boston,
MA, p.A6439
9:15 Variation in Tracheostomy Utilization for Mechanically
Ventilated Adults by Diagnosis: an Analysis of National
Trends/J.M. Kruser, S.B. Smith, R.D. Shah, C.H. Weiss, R.G.
Wunderink, Chicago, IL, p.A6440
9:30 Provider Variability in Time to Antibiotics in Patients Presenting
to the Emergency Department with Severe Sepsis/I.D. Peltan,
K.H. Mitchell, K.E. Rudd, B.A. Mann, D.J. Carlbom, T.D. Rea, C.T.L.
Hough, S.M. Brown, Seattle, WA, p.A6441
9:45 Practice Patterns and Utilization of Procalcitonin in Critically Ill
Patients with Sepsis/D.C. Chu, A.B. Mehta, A.J. Walkey, Boston,
MA, p.A6442
10:00 Sepsis Case Volume and Evidence-Based Processes of
Care/A. Fawzy, A.J. Walkey, Boston, MA, p.A6443
10:15 Potential Harm Associated with Severity-Adjusted Treatment
Variability in Fluid Resuscitation of Critically Ill Septic
Patients/J.N. Mansoori, W.T. Linde-Zwirble, P.C. Hou, E.
Havranek, I.S. Douglas, Aurora, CO, p.A6444
10:30 Is a Fluid-Conservative Strategy Optimal for All Patients with
Acute Respiratory Distress Syndrome (ARDS)? Latent Class
Analysis Indicates that ARDS Endotypes Have a Differential
Response to Fluid-Management Strategy in the NHLBI ARDS
Network Fluid and C/K.R. Famous, K. Delucchi, L.B. Ware, K. Liu,
K.N. Kangelaris, B.T. Thompson, M. Matthay, C.S. Calfee, San
Francisco, CA, p.A6445
10:45 Impact of a Physician-Based Pay-For-Performance Program on
Use of Spontaneous Breathing Trials in Mechanically
Ventilated Patients/I.J. Barbash, C.W. Seymour, S.R. Gunn, J.M.
Kahn, Pittsburgh, PA, p.A6446
D17
MINI SYMPOSIUM
“OMICS” OF ENVIRONMENTAL LUNG DISEASE
9:00 a.m. - 11:00 a.m. MOSCONE CENTER
Chairing: A.A. Litonjua, MD, MPH, Boston, MA
E. Forno, MD, MPH, Pittsburgh, PA
V.E. Ortega, MD, Winston Salem, NC
Oral Presentations
Room 2006/2008 (West Building, Level 2)
9:00 Exposure to Manufactured Nanoparticles During Gestation:
Impact on the Respiratory Tract of the Offspring in a Mouse
Model/E. Paul, M.-L. Franco-Montoya, J. Rose, J. Boczkowski, S.
Lanone, C. Delacourt, J.-C. Pairon, Creteil, France, p.A6447
9:15 Effects of Controlled Diesel Exhaust and Allergen
Co-Exposure on miRNA and Gene Expression in Humans:
Modulation of Lung Inflammatory Markers Associated with
Asthma/C.F. Rider, M. Yamamoto, O.P. Gunther, A. Singh, J.A.
Hirota, S.J. Tebbutt, C. Carlsten, Vancouver, Canada, p.A6448
9:30 Genetic and Epigenetic Regulation of MUC5B Expression in
Idiopathic Pulmonary Fibrosis/B.A. Helling, B. Pedersen, K.K.
Brown, M.P. Steele, J. Loyd, G. Cosgrove, M.I. Schwarz, S.
Groshong, C.M. Evans, T. Fingerlin, I.V. Yang, D.A. Schwartz,
Aurora, CO, p.A6449
9:45 Effect of Little Cigar Exposure on the Airway Epithelial Mucus
Barrier and Exosomal miRNA Profile/S. Abdelwahab, A. Ghosh,
B. Reidel, P. Haridass, R. Gupta, H. Dang, P. Mieczkowski, R.
Tarran, M. Kesimer, Chapel Hill, NC, p.A6450
10:00 Recent Second-Hand Smoke Exposure Is Associated with
Altered CpG Methylation Between Monozygotic Twins/
J.C.A. Lawrence, R.N. Bauer, K.C. Nadeau, R.L. Miller, New York,
NY, p.A6451
WEDNESDAY MORNING
ATS 2016 • San Francisco