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124 SUNDAY • MAY 15<br />

719 Lactate Rebound as an Independent Predictor of Mortality in<br />

Intensive Care/J. Salciccioli, P. Charlton, A. Hartley, M.<br />

Komorowski, D. Marshall, J. Shalhoub, M.C. Sykes, L.A. Celi,<br />

London, United Kingdom, p.A2732<br />

720 Highly Effective Treatment of Endothelial Disorders in Sepsis<br />

by CAR Peptide Adjuvant for Hydrocortisone Therapy/H.<br />

Okada, K. Suzuki, K. Oda, G. Takemura, C. Takada, D. Mann, M.<br />

Komatsu, S. Ogura, Gifu, Japan, p.A2733<br />

721 Therapeutic Effect of Gut-Derived Incretin Hormones in an<br />

Endotoxemic Mouse Model of Impaired Glucose Metabolism/F.<br />

Shah, S. Singamsetty, L. Guo, B. Chuan, S. McDonald, B. O’Donnell,<br />

Y. Zhang, C.P. O’Donnell, B.J. McVerry, Pittsburgh, PA, p.A2734<br />

722 Heat Shock Protein 90 (HSP90) Stabilizes a Molecular Complex<br />

of Caspase-8 and Toll-Like Receptor-4 (TLR-4) to Prolong<br />

Polymorphonuclear Neutrophil (PMN) Survival and Regulate<br />

Respiratory Burst Activity/S. Gupta, H. Amatullah, R. D’Cruz, S.<br />

Jia, J. Tsang, C. Dos Santos, J.C. Marshall, Toronto, Canada,<br />

p.A2735<br />

723 Protection Effect of Shenfuhuang Prescription on Organs of<br />

Septic Rats and its Molecular Machanism/L. Wang, X. Zhu, G.<br />

Li, Q. Liu, Beijing, China, p.A2736<br />

724 Type 2 Inflammatory Responses Protect Against<br />

Staphylococcus aureus-Induced Sepsis/P.A. Verhoef, P.A.<br />

Krishack, J. Bubeck Wardenburg, A.I. Sperling, Chicago, IL, p.A2737<br />

725 The rs805305 SNP of Dimethylarginine<br />

Dimethylaminohydrolase 2(DDAH2) Is Associated with<br />

Reduced Duration of Shock, Improved Mortality and an<br />

Elevated Plasma ADMA:SDMA Ratio in Septic Shock -<br />

Subgroup Analysis of Patients from the VANISH Trial/S.<br />

Lambden, J. Leiper, A. Gordon, London, United Kingdom, p.A7800<br />

A105<br />

POSTER DISCUSSION SESSION<br />

CRITICAL CARE : VARIABILITY IN CARE,<br />

OPPORTUNITIES FOR ADOPTION OR DEADOPTION<br />

2:15 p.m. - 4:15 p.m. MOSCONE CENTER<br />

Room 3011 (West Building, Level 3)<br />

Poster Viewing 2:15-3:00<br />

Discussion 3:00-4:15<br />

Chairing: C.R. Cooke, MD, MSc, Ann Arbor, MI<br />

J.M. Kahn, MD, MSc, Pittsburgh, PA<br />

K.S. Mathews, MD, MPH, New York, NY<br />

801 Deciding Factors for Admission: Intensive Care Versus<br />

Intermediate Care/J.T. Talbot, A. Isakov, A. Yancey, I. Bloom,<br />

G.S. Martin, J.E. Sevransky, C. Polito, Atlanta, GA, p.A2738<br />

802 Diagnosing Sepsis Is Subjective and Highly Variable: Results<br />

from a Survey of Intensivists Using Case Vignettes/C. Rhee,<br />

S.S. Kadri, R. Danner, A. Suffredini, A. Massaro, B.T. Kitch, G. Lee,<br />

K. Kleinman, R. Platt, M. Klompas, Boston, MA, p.A2739<br />

803 Antibiotic Delivery Delays and Mortality Among Patients with<br />

Sepsis: A Propensity-Matched Case-Control Study/M. Sisk,<br />

M.G. Kashiouris, S. Pedram, S.M. Hartigan, R. Naylor, K. Miller, S.<br />

Miller, R. Sampson, J. Trull, C. Mays, C.N. Sessler, Richmond, VA,<br />

p.A2740<br />

804 The Timing of Early Antibiotics and Hospital Mortality in<br />

Sepsis/V. Fielding-Singh, J.D. Greene, J.M. Baker, G.J. Escobar,<br />

V. Liu, San Francisco, CA, p.A2741<br />

805 Factors Associated in De-Escalation of Antibiotics in Critically<br />

Ill Patients with Nosocomial Pneumonia/N. Ariyoshi, J. Davis, J.<br />

Dworkin, G.P. Devendra, Honolulu, HI, p.A2742<br />

806 Antibiotic Stewardship in Medical ICU: Importance of a<br />

Multidisciplinary Approach for Antibiotic De-Escalation/G.E.<br />

Holguin, M.F. Petrini, D. Haynes, Jackson, MS, p.A2743<br />

807 How Procalcitonin Changed Antimicrobials Use in ICU Patients<br />

with Lower Respiratory Infections/S. AlSamman, K. Shawwa, J.<br />

Hong, M.A. AlSamman, C. Hayner, S. Friedstrom, J. Steinbrunner,<br />

Detroit, MI, p.A2744<br />

808 Permissive Underfeeding or Standard Enteral Feeding in<br />

Critically Ill Adults at High and Low Malnutrition Risk/Y.M.<br />

Arabi, A.S. Aldawood, S.H. Haddad, H.M. Al-Dorzi, H.M. Tamim, G.<br />

Jones, S. Mehta, L. McIntyre, O. Solaiman, M.H. Sakkijha, M.<br />

Sadat, L. Afesh, A. Kumar, S.M. Bagshaw, C. Lee, N. Salahuddin,<br />

Riyadh, Saudi Arabia, p.A2745<br />

809 Hospital Variation in Acute Hemodialysis for Sepsis in the<br />

U.S./T.S. Valley, B.K. Nallamothu, M. Heung, T.J. Iwashyna, C.R.<br />

Cooke, Ann Arbor, MI, p.A2746<br />

810 Wide Practice Variability in Fluid Resuscitation of Critically Ill<br />

Patients with Acute Respiratory Distress Syndrome<br />

(ARDS)/J.N. Mansoori, W.T. Linde-Zwirble, P.C. Hou, E. Havranek,<br />

I.S. Douglas, Denver, CO, p.A2747<br />

811 Early Hyperoxia, Neurologic Outcome, and Mortality in<br />

Post-Cardiac Arrest Syndrome/L. Hsu, R.J. Anderson, T.B.<br />

Ghafouri, S. Tyagi, J. Joshua, J.R. Beitler, La Jolla, CA, p.A2748<br />

812 Sedative Infusions in Already-Comatose Patients After<br />

Out-of-Hospital Cardiac Arrest/J. Joshua, R.J. Anderson, L. Hsu,<br />

T.B. Ghafouri, S. Tyagi, J.R. Beitler, La Jolla, CA, p.A2749<br />

813 Survey of Glucose Control Practices in All ICUs Within British<br />

Columbia, Canada/S. Yue, V. Dhingra, J.J. Ronco, C. Pamplin, S.<br />

McKeown, P. Dodek, Vancouver, Canada, p.A2750<br />

814 Trends in Mechanical Ventilation and Vasopressor Use and<br />

Relevance to Mortality Outcomes in Critical Care Settings/J.D.<br />

Raffa, R.A. Montgomery, R. Stretch, A.E.W. Johnson, L.A. Celi, T.<br />

Pollard, Cambridge, MA, p.A2751<br />

815 The Effect of Clinical Trial Results on the Use of<br />

Neuromuscular Blockade for Severe ARDS/M.P. Siedsma, T.Q.<br />

Le, J.M. Kahn, C.W. Seymour, Pittsburgh, PA, p.A2752<br />

816 Suboptimal Adherence to Low Tidal Volume and Higher PEEP<br />

Strategies in Patients with Moderate to Severe Hypoxemia/<br />

K.S. Mathews, I.H. Shalom, L.S. Richman, E.Y. Fass, L.D.<br />

Richardson, New York, NY, p.A2753<br />

ATS 2016 • San Francisco

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