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MONDAY • MAY 16 143<br />

B17<br />

MINI SYMPOSIUM<br />

TUBERCULOSIS: SUSCEPTIBILITY AND IMMUNE<br />

RESPONSE<br />

9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />

Room 3020/3022 (West Building, Level 3)<br />

Chairing: S. Schwander, MD, PhD, Piscataway, NJ<br />

P.C. Karakousis, MD, Baltimore, MD<br />

H. Koziel, MD, Boston, MA<br />

R.N. van Zyl-Smit, MBChB, PhD, Cape Town, South Africa<br />

Featured Speaker<br />

9:00 Impact of Smoke on TB Pathogenesis/R.N. van Zyl-Smit,<br />

MBChB, PhD, Cape Town, South Africa,<br />

Oral Presentations<br />

9:15 Comparison of Bronchoalveolar Lavage (BAL) Cells in Human<br />

Subjects and Cynomolgus Macaques Prior to and Following<br />

Infection with Mycobacterium Tuberculosis/R.F. Silver, A.<br />

Fraser, J.R. Jarvela, T.L. Bonfield, T. Rutledge, J. Flynn, P.L. Ling,<br />

Cleveland, OH, p.A2886<br />

9:30 Histone H3K14 Hypoacetylation and H3K27 Hyermethylation<br />

Along with HDAC1 Up-Regulation and KDM6B<br />

Down-Regulation Are Associated with Active Pulmonary<br />

Tuberculosis Disease/Y.-C. Chen, M.-C. Lin, T.-Y. Chao, S.-Y.<br />

Leung, C.-C. Wu, W.-F. Fang, Kaohsiung, Taiwan, p.A2887<br />

9:45 Up Regulation of TLR4 Expression in Leukocytes of<br />

Co-Infected HIV/TB Patients/E. Mortaz, J. Garssen, M. Marjani,<br />

M. Varahram, A.A. Velayati, I.M. Adcock, P. Tabarsi, Utrecht,<br />

Netherlands, p.A2888<br />

10:00 Serum Short Chain Fatty Acids Increase the Risk of<br />

Tuberculosis in HIV Patients on Antiretroviral Therapy and<br />

Inhibit Th1 and Th17 Immune Response/M.D. Weiden, J.C.<br />

Clemente, Y. Li, E. Friedman, C. Ruan, J. Cao, A. Pooran, M.<br />

Davids, G. Calligaro, R. Dawson, R.N. Van Zyl-Smit, K. Dheda,<br />

W.N. Rom, L. Segal, New York, NY, p.A2889<br />

10:15 Cigarette Smoke Impairs Alveolar Macrophage Migration to<br />

Mycobacterium Tuberculosis/S.M. O’Leary, S. Levitte, L.<br />

Ramakrishnan, M.P. O’Sullivan, J.M. Keane, Dublin, Ireland,<br />

p.A2890<br />

10:30 Smokers’ Alveolar Macrophages Demonstrate Impaired<br />

Glycolytic Reprogramming in Response to Mycobacterium<br />

Tuberculosis Infection/L.E. Gleeson, F.J. Sheedy, D. Triglia, S.M.<br />

O’Leary, J.M. Keane, Dublin, Ireland, p.A2891<br />

10:45 Nicotine Impairs Macrophage Control of Mycobacterium<br />

Tuberculosis by Binding to Nicotinic Acetylcholine Receptor,<br />

Activating Nfkappab and Inhibiting Autophagy/E.D. Chan, J.<br />

Stitzel, A. Bai, M. Phillips, X. Bai, Denver, CO, p.A2892<br />

B18<br />

MINI SYMPOSIUM<br />

SYMPTOM ASSESSMENT: THE PRACTICAL REALITY<br />

9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />

Room 307 (South Building, Esplanade Level)<br />

Chairing: V.M. McDonald, PhD, RN, New Lambton Heights, Australia<br />

M. Hodson, MSC, RN, London, United Kingdom<br />

Oral Presentations<br />

9:00 Routine Dyspnea Assessment Every Shift: Feasibility and<br />

Acceptance of by Nurses/K. Baker, S. Desanto-Madeya, M.<br />

Gauthier, M. Mahoney, R. Martinez, R. Banzett, Boston, MA,<br />

p.A2893<br />

9:15 Use of Validated Dyspnea Scales Increases Nurses’<br />

Confidence in Their Assessment and Treatment of Dyspnea in<br />

Palliative Care Patients/M. Yannacone, V. Carrieri-Kohlman, S.<br />

Barbour, San Francisco, CA, p.A2894<br />

9:30 Daily Measure of Quality and Intensity of Dyspnea Throughout<br />

Acute Hospitalizations/J.P. Stevens, K. Baker, C.R. O’Donnell, R.<br />

Lansing, R. Schwartzstein, R. Banzett, Boston, MA, p.A2895<br />

9:45 Patients with COPD Prioritise Symptoms Experience<br />

Differently to Respiratory Nurse Specialists/S. Prigmore, A.<br />

Caress, J. Yorke, Manchester, United Kingdom, p.A2896<br />

10:00 Dyspnoea-12 Scores Reported “These Days” Are Greater than<br />

Those Reported “Today”: Differences in People with COPD,<br />

Asthma and ILD/A.-M. Russell, K.N. Johnston, J. Yorke, M.T.<br />

Williams, London, United Kingdom, p.A2897<br />

10:15 Evaluation of Individual Activity Descriptors of the MRC<br />

Dyspnoea Scale: Do They Add Up?/J. Yorke, C. Gibons, A.<br />

Garrow, S. Tyson, J. Vestbo, D. Singh, N. Khan, P.W. Jones,<br />

Manchester, United Kingdom, p.A2898<br />

10:30 A Structural Equation Modeling Analysis of the Relationships<br />

Between Symptoms and Physical Performance in Patients<br />

with COPD/J. Lee, V.S. Fan, S. Borson, K.C. Pike, M.E. Jarrett,<br />

H.Q. Nguyen, Seattle, WA, p.A2899<br />

10:45 Fear of Dyspnea Independently Predicts ER Visits and<br />

Self-Management Abilities in COPD Patients/B. Abascal-Bolado,<br />

R.P. Benzo, Santander, Spain, p.A2900<br />

B19<br />

MINI SYMPOSIUM<br />

BEST OF PEDIATRICS<br />

9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />

Room 3006/3008 (West Building, Level 3)<br />

Chairing: M. Rosenfeld, MD, MPH, Seattle, WA<br />

A.C. Koumbourlis, MD, MPH, Washington, DC<br />

MONDAY MORNING<br />

ATS 2016 • San Francisco

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