Final Program
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WEDNESDAY • MAY 18 341<br />
10:20 TB Treatment Targets, Vaccines, and Host-Directed Therapies<br />
R. Wallis, MD, Johannesburg, South Africa<br />
10:40 Panel Discussion<br />
D11<br />
BASIC • TRANSLATIONAL<br />
SCIENTIFIC SYMPOSIUM<br />
CME Credits Available: 2.0<br />
ARDS AND INFLAMMATORY INJURY<br />
Assemblies on Allergy, Immunology and Inflammation; Critical Care;<br />
Respiratory Cell and Molecular Biology; Respiratory Structure and<br />
Function<br />
9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />
Room 3006/3008 (West Building, Level 3)<br />
Target Audience<br />
Clinical researchers, basic scientists and clinicians interested in understanding<br />
the inter-dependence between the innate immune response, excessive<br />
inflammation, and acute lung injury/ARDS.<br />
Objectives<br />
At the conclusion of this session, the participant will be able to:<br />
• understand the mechanisms which lead to differing outcomes in ARDS;<br />
• learn and understand the mechanisms contributing to inflammatory<br />
response following ALI.<br />
Acute respiratory distress syndrome (ARDS), the most severe form of ALI, has<br />
a mortality rate of approximately 40%, despite modern ICU care. The<br />
importance of inflammation in initiation and progression of acute lung injury has<br />
been previously established. Inflammasome signaling is critical in the host<br />
defense response to infectious and non-infectious agents known to contribute to<br />
lung pathology. Inflammatory responses are typically initiated by the innate<br />
immune system, leading to the production of IL-1ß and IL-18, which recruit<br />
neutrophils and monocytes to the site of infection. However, these same<br />
cytokines and cells can damage the alveolus and impair respiratory function.<br />
An important goal of this session is to illustrate how data derived from patient<br />
samples and clinically relevant animal models points to a common pathway(s)<br />
and helps to define the basic mechanisms which impacts disease outcomes in<br />
patients<br />
Chairing: C. Hardin, MD, PhD, Boston, MA<br />
T. Cohen, PhD, Gaithersburg, MD<br />
9:00 Bridging Human, Animal and In-Vitro Data<br />
M.A. Matthay, MD, San Francisco, CA<br />
9:20 Airway Responses to Bacterial Pathogens<br />
A.S. Prince, MD, New York, NY<br />
9:40 Regulation of Nod-Like Receptors in Acute Lung Injury<br />
K.M. Ridge, PhD, Chicago, IL<br />
10:00 RAGE and Acute Lung Injury<br />
J. Constantin, MD, PhD, Clermont-Ferrand, France<br />
10:20 Alveolar Epithelial Repair After Inflammatory Injury<br />
R.L. Zemans, MD, Denver, CO<br />
10:40 The Transcription Factor Miz1 in the Lung: Good or Bad?<br />
J. Liu, PhD, Chicago, IL<br />
D12<br />
CLINICAL<br />
SCIENTIFIC SYMPOSIUM<br />
CME Credits Available: 2.0<br />
ADVANCES IN TOBACCO DEPENDENCE<br />
TREATMENT FOR THE HOSPITALIZED PATIENT<br />
Tobacco Action Committee<br />
9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />
Room 130-132 (North Building, Lower Level)<br />
Target Audience<br />
Health care workers treating tobacco dependence and tobacco related disease.<br />
Objectives<br />
At the conclusion of this session, the participant will be able to:<br />
• gain new strategies to initiate a quit attempt for hospitalized smokers;<br />
• become familiar with the tools available to implement a hospital-based<br />
smoking cessation program that includes post-discharge follow up;<br />
• improve smoking cessation rates among hospitalized patients.<br />
Hospitalization marks a unique opportunity to impact the tobacco epidemic. The<br />
effective health care system must consider a number of variables in devising<br />
interventions for promoting abstinence and facilitating transition to outpatient care.<br />
In this session various aspects of tobacco dependence treatment in hospitalized<br />
smokers will be explored. Common obstacles including initial counseling of<br />
resistant patients, personalizing treatment plans, use of technology, and effective<br />
discharge planning will be reviewed.<br />
Chairing: F.T. Leone, MD, MS, Philadelphia, PA<br />
9:00 The Inpatient Tobacco Treatment Consultation<br />
F.T. Leone, MD, MS, Philadelphia, PA<br />
9:25 Implementing Hospital Cessation: The Ottawa Model<br />
S. Gilman, MD, Montreal, Canada<br />
9:50 Initiating NRT and Other Treatments<br />
D. Sachs, MD, Palo Alto, CA<br />
10:15 Transitioning into Post-Discharge Care<br />
S. Pakhale, MD, Ottowa, Canada<br />
10:35 Should We Allow E-Cigarette Use in Hospitals?<br />
D.J. Upson, MA, MD, Albuquerque, NM<br />
D13<br />
There will be a 5-minute discussion after each talk.<br />
MINI SYMPOSIUM<br />
VIRAL INFECTIONS AND ASTHMA: HOST DEFENSE<br />
AND SELF DEFEAT<br />
9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />
Chairing: J.E. Gern, MD, Madison, WI<br />
M.M. Wurfel, MD, PhD, Seattle, WA<br />
T.S. Hallstrand, MD, MPH, Seattle, WA<br />
Room 2005/2007 (West Building, Level 2)<br />
WEDNESDAY MORNING<br />
ATS 2016 • San Francisco