Final Program
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SATURDAY • MAY 14 19<br />
Target Audience<br />
Researchers and public health practitioners in respiratory and environmental<br />
health.<br />
Objectives<br />
At the conclusion of this session, the participant will be able to:<br />
• understand and apply key concepts in the design and analysis of studies of<br />
DNA methylation and lung disease;<br />
• comprehend the impact of epigenetic studies on prevention (e.g., biomarker<br />
development), diagnosis, and treatment of lung disease;<br />
• learn new and alternative approaches to epigenetic studies.<br />
Lung diseases are multi-factorial,resulting from interactions between genetic and<br />
environmental factors. Heritable and/or de novo changes in gene expression that<br />
occur without alterations in DNA sequence (epigenetic) mediate some environmental<br />
effects on lung disease. We will review state of the art approaches to designing and<br />
implementing studies of epigenetics in general and in pulmonary/critical care/sleep<br />
medicine in particular.<br />
Chairing: J.C. Celedon, MD, DrPH, Pittsburgh, PA<br />
C. Breton, ScD, Los Angeles, CA<br />
8:00 Designing Studies of DNA Methylation<br />
J.C. Celedon, MD, DrPH, Pittsburgh, PA<br />
8:40 Laboratory Assays for Epigenetic Studies<br />
S. Belinsky, PhD, Albuquerque, NM<br />
9:25 Data Analysis for Studies of DNA Methylation<br />
C. Breton, ScD, Los Angeles, CA<br />
10:10 Break<br />
10:20 Murine Studies of Epigenetics<br />
L. Kobzik, MD, Boston, MA<br />
11:05 Birth Cohort Studies of Epigenetics<br />
J. Herbstman, PhD, New York, NY<br />
11:50 MicroRNA Studies<br />
P.G. Woodruff, MD, MPH, San Francisco, CA<br />
12:35 LUNCH<br />
1:35 Twin Studies of Epigenetics<br />
J.C. Celedon, MD, DrPH, Pittsburgh, PA<br />
2:20 Break<br />
2:30 Histone Modification<br />
K.H. Albertine, PhD, Salt Lake City, UT<br />
3:15 Where Do We Go from Here?<br />
B.A. Raby, MD, MPH, Boston, MA<br />
PG22<br />
CLINICAL<br />
POSTGRADUATE COURSE<br />
CME Credits Available: 6.5<br />
DIFFICULT CLINICAL PROBLEMS IN PULMONARY<br />
AND CRITICAL CARE INFECTIONS<br />
Pre-registration and additional fees required. Continental breakfast and<br />
box lunch included. Attendance is limited.<br />
Member: $350 In-Training Member: $200<br />
Non-Member: $425 In-Training Non-Member: $300<br />
Registrants must bring a laptop to the<br />
course to view the course material.<br />
Assemblies on Microbiology, Tuberculosis and Pulmonary Infections;<br />
Clinical Problems; Critical Care<br />
8:00 a.m. - 4:00 p.m. MOSCONE CENTER<br />
Room 3014 (West Building, Level 3)<br />
Target Audience<br />
Clinicians managing patients with pulmonary and critical care acquired<br />
infections.<br />
Objectives<br />
At the conclusion of this session, the participant will be able to:<br />
• have a much greater understanding of the range of pulmonary infections<br />
that can occur in immunocompetent and immunocompromised hosts;<br />
• gain a much better appreciation of the evidence supporting different<br />
treatment strategies in pulmonary infections;<br />
• have a much better knowledge of new diagnostic tests, treatments and<br />
outcome measures that can be applied in their local setting.<br />
This course will provide clinicians with a broad overview and an update of the current<br />
challenging issues in the management of pulmonary and critical care infections<br />
including typical bacterial pneumonia, mycobacterial, fungal, and viral infections as<br />
well as general approaches to infections in the immunocompromised host.<br />
Chairing: C.A. Hage, MD, Indianapolis, IN<br />
K.A. Crothers, MD, Seattle, WA<br />
K.S. Knox, MD, Tucson, AZ<br />
8:00 ICU Acquired CLABSI: Prevention and Management in the<br />
Accountable Care Era<br />
I.I. Raad, MD, Houston, TX<br />
8:30 Emerging Viral Respiratory Tract Infections<br />
T.E. West, MD, MPH, Seattle, WA<br />
9:00 What Are the Big Changes in the New and Upcoming VAP/HAP<br />
Treatment Guidelines?<br />
M.L. Metersky, MD, Farmington, CT<br />
9:30 Panel Discussion<br />
M.L. Metersky, MD, Farmington, CT<br />
I.I. Raad, MD, Houston, TX<br />
T.E. West, MD, MPH, Seattle, WA<br />
9:45 Break<br />
10:00 Empyema and Other Pleural Infections<br />
Y.C.G. Lee, MBChB, PhD, Perth, Australia<br />
SATURDAY<br />
ATS 2016 • San Francisco