Final Program
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36 SUNDAY • MAY 15<br />
9:15 Hyperpolarized Xenon-129 MRI: A New Tool to Evaluate<br />
COPD/K. Qing, Y.M. Shim, N.J. Tustison, T.A. Altes, K. Ruppert,<br />
J.F. Mata, B. Mehrad, G.W. Miller, S. Guan, I.C. Ruset, F.W.<br />
Hersman, J.P. Mugler, Charlottesville, VA, p.A1049<br />
9:30 Testing the Fletcher-Peto Assumptions Using Pulmonary<br />
Imaging Biomarker Longitudinal Measurements/R.L. Eddy, D.<br />
Pike, K. Sheikh, G. Paulin, M. Kirby, D.G. McCormack, G. Parraga,<br />
London, Canada, p.A1050<br />
9:45 Prediction of Future Lung Function Decline from Baseline<br />
Hybrid Hyperpolarized 3He MRI in Current Smokers and COPD<br />
Patients/H. Hamedani, S. Kadlecek, Y. Xin, M. Cereda, H. Gatens,<br />
J. Naji, S. Siddiqui, M. Pourfathi, M. Rossman, R.R. Rizi,<br />
Philadelphia, PA, p.A1051<br />
10:00 Regional Ventilation Defects Measured on Hyperpolarized 3He<br />
MRI Are Associated with Mucus Plugging Measured on CT in<br />
Asthma/E. Dunican, J.V. Fahy, D.G. Mummy, S. Fain, E.A.<br />
Hoffman, B.M. Elicker, D.S. Gierada, J.D. Newell, Jr, N.N. Jarjour,<br />
M. Castro, S. Nagle, San Francisco, CA, p.A1052<br />
10:15 Segmental Ventilation Defect Percentage in Hyperpolarized<br />
3He MRI in Asthma Is Associated with Airway Wall Thickness<br />
Measured on CT/D.G. Mummy, W. Zha, R. Sorkness, L.C.<br />
Denlinger, J.D. Quirk, D. Gierada, J.C. Woods, M. Castro, N.N.<br />
Jarjour, S. Fain, Madison, WI, p.A1053<br />
10:30 What Does Magnetic Resonance Imaging Signal-Intensity Mean<br />
in Asthma?/K. Sheikh, F. Guo, S. Svenningsen, A. Ouriadov, D.P.<br />
Capaldi, R.L. Eddy, D.G. McCormack, G. Parraga, London,<br />
Canada, p.A1054<br />
10:45 Measurement of Asthma Treatment Response Using<br />
Free-Breathing 1H Ventilation MRI/D.P. Capaldi, K. Sheikh, S.<br />
Svenningsen, M. Kirby, H. Coxson, D.G. McCormack, G. Parraga,<br />
London, Canada, p.A1055<br />
A21<br />
POSTER DISCUSSION SESSION<br />
CHRONIC AIRWAY INFLAMMATION: MICROBIAL<br />
INFLUENCE<br />
9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />
Room 2024 (West Building, Level 2)<br />
Poster Viewing 9:00-9:45<br />
Discussion 9:45-11:00<br />
Chairing: J.S. Deshane, PhD, Birmingham, AL<br />
M.R. Stampfli, PhD, Hamilton, Canada<br />
P.S. Foster, PhD, Callaghan, Australia<br />
S. Bozinovski, PhD, Bundoora, Australia<br />
601 The Effects of Smoking on The Lower Airway DNA Virome/B.C.<br />
Keller, G. Zhao, B.G. Wu, J.C. Clemente, L.N. Segal, St. Louis,<br />
MO, p.A1056<br />
602 Longitudinal Changes in Airway Microbiome Signatures and<br />
Immunoregulatory Cell Dynamics Following Bronchial<br />
Thermoplasty/J.S. Deshane, J. Trevor, Y. Wang, D. Zhi, M.<br />
Curtiss, F. Wang, P.G. Eipers, V.D.P. William, C. Morrow, M.T.<br />
Dransfield, Birmingham, AL, p.A1057<br />
603 A Study to Define the Microbiome of the Asthmatic Airway/E.<br />
Hunt, S. Lapthorne, C. Ward, J. Eustace, B. Plant, D. Murphy, J.<br />
MacSharry, Cork, Ireland, p.A1058<br />
604 Nasal Microbiome Composition Varies over Time in Pediatric<br />
Asthma/M. Perez-Losada, L. Alamri, A. Goldstein, K.A. Crandall,<br />
R.J. Freishtat, Ashburn, VA, p.A1059<br />
605 The Infant Gut Microbiome, Respiratory Infection, and<br />
Repeated Wheeze in the First Year of Life: Findings from the<br />
Vitamin D Antenatal Asthma Reduction Trial (VDAART)/J.E.<br />
Sordillo, Y. Zhou, M. McGeachie, N. Lange, N. Laranjo, J. Savage,<br />
V.J. Carey, E. Sodergren, S.T. Weiss, D.R. Gold, G. Weinstock,<br />
A.A. Litonjua, Boston, MA, p.A1060<br />
606 Factors Influencing the Infant Gut Microbiome at Age 3-6<br />
Months: Findings from the Ethnically Diverse Vitamin D<br />
Antenatal Asthma Reduction Trial (VDAART)/J.E. Sordillo, Y.<br />
Zhou, M. McGeachie, N. Lange, N. Laranjo, J. Savage, V.J. Carey,<br />
G. Weinstock, E. Sodergren, D.R. Gold, S.T. Weiss, A.A. Litonjua,<br />
Boston, MA, p.A1061<br />
607 Utilizing the Collaborative Cross Cohort to Identify the<br />
Genetics of Host Responses to Respiratory Syncytial<br />
Virus/A.S. Buntzman, D. Francisco, K. Addison, A. Manne, J.<br />
Frelinger, J.G. Ledford, F.D. Martinez, M. Kraft, Tucson, AZ,<br />
p.A1062<br />
608 Rhinovirus-Induced Production of PGE2 by Asthmatic<br />
Bronchial Epithelial Cells: Inverse Association with Strain<br />
Pathogenicity/L. Shi, E. Roti Roti, A. Guadarrama, P. Fichtinger,<br />
L.C. Denlinger, Madison, WI, p.A1063<br />
609 Group A Streptococcus (GAS) Indudes Bronchial Asthma<br />
(BA)/T. Matsuda, Misato-shi, Saitama, Japan, p.A1064<br />
610 Bronchial Microbiome in Severe Persistent Oral<br />
Corticosteroid-Dependent Asthma/L. Millares, G. Bermudo, M.<br />
Garcia-Nunez, C. Grimau, N. Martinez-Lopez, V. Perez-Brocal, C.<br />
Domingo, E. Monso, Sabadell, Spain, p.A1065<br />
611 Effects of Recombinant Myristoylated Rhinovirus VP4 Protein<br />
on Primary Alveolar Macrophages/J.K. Bentley, S. Jaipalli, M.<br />
Han, J. Lei, M.B. Hershenson, Ann Arbor, MI, p.A1066<br />
612 Mycobiome Analysis of Lower Airway Secretions from<br />
Children with Fungal-Sensitized Severe-Persistent<br />
Asthma/E.M. St. John Sutton, A. Tsuang, S. Viswanathan, R.<br />
Burke, D.L. Goldman, A.G. Vicencio, New York, NY, p.A1067<br />
613 Gene Expression and Protein Secretion in Normal Versus<br />
Diseased Human Lung Tissue/L. Sherman, D. Mohn, K. Miner, C.<br />
Vezina, J.A. Johnston, Thousand Oaks, CA, p.A1068<br />
614 Infants with Early Wheeze Have Decreased Lung Function and<br />
Microbial Changes of Their Upper Airway at 3 Months of Age/K.<br />
Kloepfer, S. Srivatsa, J.E. Hatch, D. Nelson, S. Janga, S.D. Davis,<br />
Indianapolis, IN, p.A1069<br />
ATS 2016 • San Francisco