Final Program

MONDAY • MAY 16 195
P1013
P1014
P1015
P1016
P1017
P1018
Excessive Rac2 Activity in ZZ-Alpha-1 Antitrypsin Deficient
Individuals and the Beneficial Effect of Alpha-1 Augmentation
Therapy on Aberrant Neutrophil Degranulation/S.A. Landers, F.
Gargoum, N. Lacey, M. White, E. Reeves, N.G. McElvaney, Dublin,
Ireland, p.A4088
Differential Association of Macrophage Migration Inhibitory
Factor (MIF) Promoter Polymorphism with Emphysema in
HIV-Infected Compared to Uninfected Patients/A. Berical, K.A.
McGinnis, L. Yu, C. Zhang, L. Leng, R. Bucala, K.A. Crothers, P.J.
Lee, M. Sauler, New Haven, CT, p.A4089
Cytoskeletal and Mitochondrial Genes as New Targets in the
Protection of Airway Epithelial Cells Against Cigarette
Smoke/C. Kliment, Y. Liu, S. Claypool, R. Sihaye, D. Robinson,
Baltimore, MD, p.A4090
Transforming Growth Factor Beta Affects MiRNA Expression
in Control and COPD Fibroblasts/J. Ong, W. Timens, V.
Rajendran, A. Algra, A. Spira, M. Lenburg, J. Campbell, D.S.
Postma, A. Van Den Berg, J.L. Kluiver, C.A. Brandsma, Groningen,
Netherlands, p.A4091
miR-199a-5p, miR-598 and miR-320a Are Regulated by NkB and
Decreased in Monocytes of ZZ Individuals Receiving Alpha-1
Antitrypsin Augmentation Therapy/T.M. Hassan, T. Carroll, S.
O’Neill, N.G. McElvaney, C.M. Greene, Dublin, Ireland, p.A4092
Muc5b Deficiency Worsens Airway Hyperreactivity in Allergen
Challenged Mice/C.M. Evans, D. Raclawska, A. Stefanski, B.S.
Bochner, W. Janssen, Aurora, CO, p.A7842
THEMATIC POSTER SESSION
P1474
P1475
P1476
P1477
P1478
P1479
P1480
Effects of Repeated Carbon Black Nanoparticle Exposures on
Healthy and Nitrogen Dioxide Pre-Damaged Mice Lungs/N.
Schreiber, E. Kotte, B. Muller, Marburg, Germany, p.A4096
Targeting Sphingosine-1-Phosphate Lyase to Enhance Lung
S1P and Reduce Experimental Cigarette Smoke-Induced
Chronic Lung Injury and Remodeling/E. Beatman, C. Poirier,
K.A. Serban, E. Berdyshev, J. Saliba, M. Justice, T. Ovarecz, D.J.
Zambrowicz, K. Schweitzer, I. Petrache, Denver, CO, p.A4097
Cigarette Smoke Induces Human Airway Epithelial Senescence
Via Growth Differentiation Factor 15 (GDF15) Production/
Q. Wu, D. Jiang, J.L. Matsuda, K. Ternyak, B. Zhang, H.W. Chu,
Denver, CO, p.A4098
The Presence of Serotonin in Cigarette Smoke - A Possible
Mechanism in Cigarette Smoke-Induced Airway
Inflammation/Y. Cui, W.K.W. Lau, K.W.K. Liu, M.S.M. Ip, J.C.W.
Mak, Hong Kong, Hong Kong Prc, p.A4099
Pathophysiologic Implications of E-Cigarette Exposure on
Airway Epithelial Ion Transport and Mucociliary Clearance/M.D.
Fain, V.Y. Lin, S.V. Raju, L. Tang, C. Fernandez, M. Mazur, J.E.
Blalock, P.L. Jackson, S. Rowe, Birmingham, AL, p.A4100
Cigarette Smoke-Induced Downregulation of the Epithelial Cell
Enriched WNT Receptor Fzd4 Contributes to Reduced
Wnt/b-Catenin Signaling and Alveolar Epithelial Cell
Proliferation in COPD/W. Skronska-Wasek, K. Mutze, H.A.
Baarsma, D.E. Wagner, M. Stornaiuolo, M. Konigshoff, Munich,
Germany, p.A4101
Impact of Tobacco Smoke on Upper Airway Dendritic Cell
Accumulation and Their Regulation by Human Sinonasal
Epithelial Cells/J.K. Mulligan, B.P. O’Connell, W. Pasquini, R.
Mulligan, C. Atkinson, R. Schlosser, Charleston, SC, p.A4102
MONDAY MORNING
B60
SMOKING AND PARTICULATES IMPACT ON LUNG
HEALTH
9:00 a.m. - 4:15 p.m. MOSCONE CENTER
Viewing: Posters will be on display for entire session.
Area M, Hall D (North Building, Lower Level)
Discussion: 11:00-11:45: authors will be present for individual discussion
11:45-12:45: authors will be present for discussion with assigned facilitators
P1471
P1472
P1473
Identification of IGSF3, a Previously Uncharacterized Gene
Linked to an Unusually Severe Case of Emphysema that Is
Decreased Both In Vivo and In Vitro in Response to Cigarette
Smoke/K. Schweitzer, N. Rush, N. Jinawath, R. Yonescu, A.
Panoskaltsis-Moratori, C.A. Griffin, D.B. Pearse, I. Petrache,
Denver, CO, p.A4093
Total Particulate Matter Concentration Skews the Gene
Expression Pattern in Cigarette Smoke-Exposed Mice Towards
an Inflammatory Phenotype: A Gene-Expression Study/
G. Vanderstocken, A. Dvorkin-Gheva, A.O. Yildirim, C.-A.
Brandsma, M. Obeidat, Y. Bosse, J.A. Hassell, M.R. Stampfli,
Hamilton, Canada, p.A4094
Effects of Straw Burning Particulate Matters to Pulmonary
Fibrosis Mice Model and the Intervention of NAC/Y. Li, D.
Weng, Shanghai, China, p.A4095
P1481
P1482
P1483
P1484
P1485
P1486
Differential and Tissue Specific Autophagic Responses to
Cigarette Smoke Exposure/M.A. Pabon, F. Malick, K.C. Ma, K.
Mizumura, S. Hisata, H.C. Lam, M. Choi, A.M.K. Choi, S.M.
Cloonan, New York, NY, p.A4103
Hexadimethrine Bromide Prevents Acute Mortality in Rats
After Inhalation of Sulfur Mustard Analog, 2-Chloroethyl Ethyl
Sulfide (CEES)/N. Mariappan, M. Husain, I. Zafar, S. Ahmad, A.
Ahmad, Birmingham, AL, p.A4104
Secondhand Smoke Diminishes Airway Epithelial Ion
Transport In Vitro and In Vivo and Is Partially Blocked by
Antioxidant Therapy/L.W. Rasmussen, H. Fortinberry, S. Byzek,
L. Tang, S. Rowe, S.V. Raju, Birmingham, AL, p.A4105
Hydrogen Therapy Attenuates Bronchial Inflammation After
Smoke Inhalation Injury in Sheep/B. Enkhataivan, S. Jacob, E.
Lopez, S. Fukuda, K. Ihara, H. Hawkins, P. Enkhbaatar, R. Cox,
Galveston, TX, p.A4106
Cigarette Smoke Alters the Biomechanical Properties of
Airway Eithelial Cells/K. Brune, H. Lam, M. Wang, H.M. Yong,
S.S. An, D.N. Robinson, V.K. Sidhaye, Baltimore, MD, p.A4107
Cadmium in the Peripheral Airways of Tobacco Smokers with
and Without COPD/B. Levänen, B.-M. Sundblad, J. Ji, K.
Midander, A. Julander, K.F. Che, K. Larsson, L. Palmberg, A.
Linden, Stockholm, Sweden, p.A4108
ATS 2016 • San Francisco