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338 WEDNESDAY • MAY 18<br />

Objectives<br />

At the conclusion of this session, the participant will be able to:<br />

• explore issues related to respiratory symptom managment and respiratory<br />

symptom clusters with a focus on cough;<br />

• identify a theoretical understanding of the relationship of psychologic symptoms<br />

and chronic cough and to understand the role of speech pathology in the<br />

managment of chronic cough;<br />

• become aware of recent finding of systematic reviews and guidelines related to<br />

the diagnosis and management of chronic refractory cough.<br />

This session will use interprofessional inquiry and recent findings from the literature<br />

to broaden the attendees understanding of the symptom of chronic cough and<br />

refractory chronic cough and its management in 2016.<br />

Chairing: P.M. Meek, RN, PhD, Denver, CO<br />

A.M. Russell, MSc, London, United Kingdom<br />

9:00 Reflections from Symptom Management<br />

P.M. Meek, RN, PhD, Denver, CO<br />

9:15 Respiratory Symptom Clusters<br />

J. Yorke, PhD, RN, Manchester, United Kingdom<br />

9:30 Examining Change in Symptoms of Depression, Anxiety, and<br />

Stress in Adults After Treatment of Chronic Cough<br />

C.L. French, PhD, RN, Worcester, MA<br />

9:45 Update Refractory Chronic Cough and Management<br />

P.G. Gibson, MBBS, Newcastle, Australia<br />

10:00 The Role of the Speech Pathologist and Speech Pathology in<br />

the Management of Chronic Cough<br />

A.E. Vertigan, PhD, MBA, BAppSc(Sp.Path), Newcastle, Australia<br />

10:15 Is the Refractory Cough of a Psychogenic Nature a Habit or an<br />

Undiagnosed Tic Cough?<br />

R.S. Irwin, MD, Worcester, MA<br />

10:30 Panel Discussion<br />

D6<br />

CLINICAL • TRANSLATIONAL<br />

SCIENTIFIC SYMPOSIUM<br />

CME Credits Available: 2.0<br />

CANNABIS, CANNABIMIMETICS, AND OPIATES IN<br />

SLEEP AND BREATHING<br />

Assemblies on Sleep and Respiratory Neurobiology; Behavioral Science and<br />

Health Services Research; Pediatrics<br />

9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />

Room 2001/2003 (West Building, Level 2)<br />

Target Audience<br />

Pulmonologists, pediatricians, respiratory therapists, nurses practitioners,<br />

sleep medicine research scientists, epidemiologists, public health providers<br />

and health services researchers.<br />

Objectives<br />

At the conclusion of this session, the participant will be able to:<br />

• discuss neurodevelopmental and respiratory effects of cannabis use in<br />

adolescents and young adults;<br />

• learn emerging data on effects of cannabis on sleep and novel therapeutic<br />

applications of cannabimetic drugs in sleep related breathing;<br />

• review effects of opioids on sleep related breathing and discuss ampakines;<br />

a novel therapy for opioid induced respiratory depression.<br />

Legalization of cannabis in the U.S. and other countries has led to increasing<br />

medicinal and recreational use of cannabis. This symposium will describe the<br />

known effects of cannabis on neurodevelopment of adolescents and its effects<br />

on sleep. Current and potential therapeutic uses of cannabis and<br />

cannabimimetics in sleep and breathing disorders will be discussed. Acute and<br />

chronic use of opioids in hospitalized patients, perioperative settings and for<br />

opioid use disorders is increasingly prevalent. Effects of opioids on sleep related<br />

breathing and novel preclinical pharmacologic interventions to reverse opioid<br />

effects on breathing will be reviewed.<br />

Chairing: B. Prasad, MD, MS, Chicago, IL<br />

L. Kheirandish-Gozal, MD, MSc, Chicago, IL<br />

9:00 A Patient’s Perspective<br />

J. Jorgensen, Vista, CA<br />

9:05 Opioid-Induced Sleep Apnea: Precursor to Periodicity<br />

S. Chowdhuri, MD, MS, Detroit, MI<br />

9:25 Ampakine Therapy for Alleviating Opioid-Induced Respiratory<br />

Depression<br />

J.J. Greer, PhD, Edmonton, Canada<br />

9:50 Cannabis and Human Sleep: What Have We Learned So Far?<br />

K. Babson, PhD, Menlo Park, CA<br />

10:10 Neurodevelopmental and Respiratory Effects of Cannabis in<br />

Adolescents and Adults<br />

R. Bhattacharjee, MD, San Diego, CA<br />

10:25 Cannabinoids: Novel Translational Potential for Sleep Apnea<br />

Therapy?<br />

D.W. Carley, PhD, Chicago, IL<br />

D7<br />

There will be a 5-minute discussion after each talk.<br />

BASIC • CLINICAL • TRANSLATIONAL<br />

SCIENTIFIC SYMPOSIUM<br />

CME Credits Available: 2.0<br />

EXPLOITING GPCRS FOR NEW AND IMPROVED<br />

ASTHMA MEDICINE<br />

Assemblies on Respiratory Structure and Function; Allergy, Immunology<br />

and Inflammation; Respiratory Cell and Molecular Biology<br />

9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />

Room 2002/2004 (West Building, Level 2)<br />

Target Audience<br />

Basic, translational and clinical scientists who wish to learn about the exciting<br />

discoveries of new targets for asthma therapy, and how these targets are<br />

being validated both in vitro and in vivo.<br />

Objectives<br />

At the conclusion of this session, the participant will be able to:<br />

ATS 2016 • San Francisco

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