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WEDNESDAY • MAY 18 349<br />

918 Intranasal Treatment with Bacteriophage Rescue Mice from<br />

Acinetobacter Baumannii-Mediated Pneumonia/C.Q. Bai, Z.Q.<br />

Mi, Y. Wang, X.P. An, X. Yuan, W.K. Niu, H.Y. Liu, P.Y. Li, Y.N.<br />

Liu, Y.Z. Feng, Y. Huang, X. Zhang, Z. Zhang, H. Fan, F. Peng,<br />

Y.G. Tong, Beijing, China, p.A6553<br />

919 Relationship of Mucosal Antibodies to Non-Typeable<br />

Haemophilus influenzae (NTHi) Colonisation of the COPD<br />

Airway/K.J. Staples, S. Thomas, S. Taylor, K. Ostridge, K. Cox, A.<br />

Richardson, A.C. Tuck, S.C. Clarke, A. Gorringe, T.M.A. Wilkinson,<br />

Southampton, United Kingdom, p.A6554<br />

920 Macrophage Galactose-Type Lectin-1 (MGL1) Deficiency Is<br />

Associated with Increased Lung Pathology and<br />

Hyperinflammation in Gram-Negative Pneumonia/J. Sharma,<br />

C.N. Jondle, A. Sharma, T.J. Simonson, B.B. Mishra, Grand Forks,<br />

ND, p.A6555<br />

921 Macrophage-Colony Stimulating Factor in Gram-Negative<br />

Pneumonia: Dynamic Protection of Lung and Liver<br />

Mononuclear Phagocytes/B. Mehrad, A. Bettina, Z. Zhang, K.R.<br />

Michels, R.E. Cagnina, A. Kadl, M. Burdick, Charlottesville, VA,<br />

p.A6556<br />

922 Carbapenem Resistent K. Pneumoniae ST258 Evade Calcium<br />

and Calpain Dependent Neutrophil Killing/H. Penaloza, D. Ahn,<br />

M. Wickersham, D. Parker, S. Bueno, A.S. Prince, Santiago, Chile,<br />

p.A7895<br />

923 Recruited Monocytic-Myeloid Derived Suppressor Cells<br />

(M-MDSCs) Dominate the Immune Response to Klebsiella<br />

pneumoniae ST258 in Bacterial Pneumonia/D. Ahn, H.<br />

Penaloza, M. Wickersham, A.S. Prince, New York, NY, p.A7896<br />

924 Flagellin Within Pseudomonas Aeruginosa Induce Neutrophil<br />

Pyroptosis Through NLRC4 Inflammasome Activation/J.-H.<br />

Ryu, Seoul, Korea, Republic of, p.A7897<br />

925 DNA-Delivery of Monospecific and Bispecific Monoclonal<br />

Antibodies Targeting Pseudomonas Aeruginosa Protect Mice<br />

from Lethal Pneumonia/A. DiGiandomenico, A. Patel, T. Smith, A.<br />

Keller, S.T.C. Elliot, L. Wachter, J. McAuliffe, S. Ramos, K.<br />

Broderick, J. Yan, A. Khan, D.H. Park, M. Wise, M. Karuppiah, S.<br />

Flingai, L. Humeau, N. Sardesai, C. Stover, D. Weiner,<br />

Gaithersburg, MD, p.A7898<br />

D25<br />

POSTER DISCUSSION SESSION<br />

NEONATAL AND CONGENITAL LUNG DISEASES<br />

9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />

Room 3011 (West Building, Level 3)<br />

Poster Viewing 9:00-9:45<br />

Discussion 9:45-11:00<br />

Chairing: L.M. Nogee, MD, Baltimore, MD<br />

J. Wambach, MD, St. Louis, MO<br />

C.V. Lal, MD, Birmingham, AL<br />

801 Treatment of Neonatal Hyperoxia Lung Injury with<br />

Differentiated hiPSCs/C.T. Drinnan, T.J. Jensen, A. Mitchell, S.<br />

Vadasz, C.M. Finck, Farmington, CT, p.A6557<br />

802 Pulmonary Vasculature in Infants with Down Syndrome Is<br />

Underdeveloped/D. Bush, C. Galambos, S.H. Abman, Aurora, CO,<br />

p.A6558<br />

803 Identification of Vitamin D Sensitive Pathways During Lung<br />

Development/L. Chen, R. Wilson, E. Bennett, G. Zosky, Hobart,<br />

Australia, p.A6559<br />

804 Temporal, Spatial and Functional Changes Characterize<br />

PDGFRa Expressing Fibroblasts During Sacculation and<br />

Alveolarization/A.-K. Perl, Cincinnati, OH, p.A6560<br />

805 Identification of Optimal Time Points and Proteomic Profiling<br />

During Murine Lung Alveolar Septation/T. Nicola, E. Sefer, C.R.<br />

Espinoza, F. Ahangari, D. Chhabra, J. Hagood, N. Kaminski, Z.<br />

Bar-Joseph, N. Ambalavanan, Birmingham, AL, p.A6561<br />

806 IL-1Ra Protects Against Impaired Alveolar Development and<br />

Airway Fibrosis but Not Airway Hyperresponsiveness in a<br />

Mouse Model of Bronchopulmonary Dysplasia/J.E. Bourke, S.G.<br />

Royce, E. Lamanna, M. Lam, C. Donovan, C. Bui, M. Nold, C. Nold,<br />

Clayton, Australia, p.A6562<br />

807 Inflammation Downregulates Fibulin-5 Expression and<br />

Disrupts Elastic Fiber Assembly During Saccular Stage Lung<br />

Development/J.T. Benjamin, R. Van Der Meer, L.R. Young, T.S.<br />

Blackwell, Nashville, TN, p.A6563<br />

808 A Role for the Accessory Type III Transforming Growth<br />

Factor-b Receptor in Post-Natal Lung Alveolarization/A.E.<br />

Pozarska, G. Niess, W. Seeger, R.E. Morty, Bad Nauheim,<br />

Germany, p.A6564<br />

809 Monocyte-Centred Inflammatory Response Characterizing<br />

Early Stages of BPD Development in the Preterm Infant/P. Oak,<br />

M. Koschlig, A. Windhorst, N. Jain, T. Reicherzer, H. Ehrhardt, M.<br />

Frankenberger, C.M. Alvira, M. Schwarz, O. Eickelberg, A.<br />

Hilgendorff, Munich, Germany, p.A6565<br />

810 Echocardiographic and Catheterization Patterns in Pediatric<br />

Patients with Secondary Pulmonary Arterial Hypertension Due<br />

to Bronchopulmonary Dysplasia/A. Singh, B. Feingold, B.<br />

Rivera-Lebron, S. Drant, Pittsburgh, PA, p.A6566<br />

811 Determining the Dose-Response Curve Needed to Translate<br />

Pulmonary Macrophage Transplantation (PMT) Therapy to<br />

Children with Hereditary Pulmonary Alveolar Proteinosis/P.I.<br />

Arumugam, T. Suzuki, A. Sallese, C. Chalk, D. Black, B. Carey,<br />

B.C. Trapnell, Cinicnnati, OH, p.A6567<br />

812 Quantitative Measures of Ground Glass Opacities Correlate<br />

with Use of Daytime Oxygen in Neuroendocrine Cell<br />

Hyperplasia of Infancy/D.R. Spielberg, A. Brody, J.C. Woods, C.<br />

Towe, Cincinnati, OH, p.A6568<br />

813 A Novel Role for Transforming Growth Factor Beta-Induced<br />

Protein in Promoting Pulmonary Endothelial Migration in the<br />

Alveolar Lung/M. Liu, S.P. Rao, C. Husted, G. Umbach, C.M.<br />

Alvira, Stanford, CA, p.A6569<br />

814 Muring Lung Lipofibroblast Lineage Tracing/A. Ntokou, R.E.<br />

Morty, W. Seeger, K. Ahlbrecht, Bad Nauheim, Germany, p.A6570<br />

WEDNESDAY MORNING<br />

ATS 2016 • San Francisco

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