296 TUESDAY • MAY 17 P1506 P1507 P1508 P1509 Facilitator: P1510 P1511 P1512 P1513 P1514 Facilitator: P1515 P1516 P1517 P1518 P1519 Remembering the Ancestral Language: Mammalian Mitochondria Directly Recognize and Respond to Bacterial Quorum Signals/J.L. Kuck, O. Dougherty, C. Moore, T. Luong, L. Letterman, S. Orfield, J.P. Fessel, E. Brittain, Q.S. Wells, Nashville, TN, p.A5777 Macrophage Akt1-Mediated Mitochondrial Biogenesis Regulates Pulmonary Fibrosis/J. Casey, A.B. Carter, Birmingham, AL, p.A5778 Mitochondrial Catalase Enforced Expression (MCAT-EE) Transgenic Mice Are Protected Against Asbestos- and Bleomycin-Induced Lung Fibrosis in Part Via Beneficial Effects on AECs/P. Cheresh, S.-J. Kim, R.P. Jablonski, A. Yeldandi, L. Morales Nebreda, Y. Cheng, M. Chi, R. Piseaux, K.M. Ridge, C.M. Hart, N. Chandel, G.S. Budinger, D. Kamp, Chicago, IL, p.A5779 Mitochondrial ROS Induce Up-Regulation of SIRT1 in LPS-Induced Acute Lung Injury/Y.C. Lee, S.R. Kim, H.J. Kim, S.H. Kim, S.Y. Park, Jeonju, Korea, Republic of, p.A5780 R. Lucas, PhD, Augusta, GA Bronchial Epithelial Calcium Metabolism Impairment in Smokers: Decreased ORAI3 Signaling Involved in Cilia Beating/A. Fort, L. Knabe, K. Khelloufi, D. Gras, N. Molinari, S. Richard, P. Chanez, I. Vachier, A. Bourdin, Montpellier, France, p.A5781 ASIC1a/aEnac Hybrid Channels Contribute to Alveolar Fluid Clearance/D.C. Eaton, P. Trac, O. Al-Khalili, M. Greenlee, Atlanta, GA, p.A5782 AMP-Activated Protein Kinase Deactivation and Lung Injury in C57BL/6 Mice Fed Chronic-Binge Ethanol/L. Kaphalia, B.S. Kaphalia, W.J. Calhoun, Galveston, TX, p.A5783 Resolution of Acute Lung Injury Induced by Whole Gastric Juice in the Hamster/G.R. Borzone, J. Araos, M. Meneses, P. Ayala, Santiago, Chile, p.A5784 Follistatin Like-1 Aggravates Radiation-Induced Lung Injury/Y. Fang, L. Wang, Z. Chen, W. Ning, Tianjin, China, p.A5785 S.P. Reddy, PhD, Chicago, IL Overexpression of IL-38 Protein in the Lungs of Drug Induced Lung Injury/M. Tominaga, M. Okamoto, T. Kawayama, S. Kaieda, M. Matsuoka, Y. Sakazaki, T. Kinoshita, T. Hoshino, Kurume, Japan, p.A5786 Acid Sphingomyelinase Is a Novel Regulator of LYNUS and Autophagy/M. Justice, C. Poirier, K. Schweitzer, J. Saliba, I. Petrache, Denver, CO, p.A5787 Low Phosphate Diet Arrests and Reverses Stone Accumulation and Acute Lung Injury in Mice with Pulmonary Alveolar Microlithiasis/Y. Uehara, N.M. Nikolaidis, A. Saito, L. Pitstick, H. Wu, H. Amlal, K. LaSance, J.C. Woods, J. Guo, F.X. McCormack, Cincinnati, OH, p.A5788 Characterize the Lung Extracellular Vesicles in the Presence of Oxidative Stress/H. Lee, D. Zhang, H.-G. Moon, J.H. Hwang, Y. Jin, Boston, MA, p.A5789 Ischemic Lung Injury Following Cardio-Pulmonary Bypass (CPB) Is Associated with Inflammation and Differentiation/A.L. Durham, E. Al Jaaly, F. Fiorentino, P. Brook, K. Heesom, P. Lavender, G. Angelini, I. Adcock, London, United Kingdom, p.A5790 C68 THEMATIC POSTER SESSION IMMUNE CELL INTERACTIONS IN COPD 9:00 a.m. - 4:15 p.m. MOSCONE CENTER Viewing: Posters will be on display for entire session. Area L, Hall D (North Building, Lower Level) Discussion: 11:00-11:45: authors will be present for individual discussion 11:45-12:45: authors will be present for discussion with assigned facilitators P1284 P1285 P1286 P1287 P1288 P1289 P1290 P1291 P1292 P1293 P1294 Recombinant Human Granulocyte Colony-Stimulating Factor Versus Bone Marrow Mononuclear Cells in Treatment of Pulmonary Emphysema Model/M.K. El Badrawy, N. Shalabi, M.A. Mohamed, A. Ragab, N. Anber, H.W. Abdelwahab, M.A. Sobh, Y. Khater, A. Abdel Hamid, Mansoura, Egypt, p.A5791 GM-CSF Drives Human Lung Tissue Macrophages Towards a More Pro-Inflammatory Phenotype/J. Tilman, P.J. Barnes, L. Donnelly, London, United Kingdom, p.A5792 Differential Effects of Budesonide and Fluticasone Propionate in Human Bronchial Epithelial Cells Exposed to Streptococcus Pneumonia and Viral Mimetic Poly-(I:C)/I.H. Heijink, M.R. Jonker, D.S. Postma, M. Van Den Berge, Groningen, Netherlands, p.A5793 Biology of the Circulating CD45+Col1+ Cells During the Pathogenesis of Pulmonary Emphysema/Y.M. Shim, M. Burdick, K. Qing, T.A. Altes, J.P. Mugler, B. Mehrad, C.E. Rose, Jr., Charlottesville, VA, p.A5794 The Decrease of TRPV2 Expression in Alveolar Macrophage by Cigarette Smoke Exposure Raises Chronic Inflammation in Lung/H. Masubuchi, M. Ueno, T. Maeno, K. Hara, K. Yamaguchi, T. Suga, M. Kurabayashi, Maebashishi, Japan, p.A5795 Aberrant Airway Epithelial Differentiation Resulting from Cigarette Smoke Exposure Leads to Loss of Constitutive Host Defence Protein Expression/A.M. Van Der Does, G. Amatngalim, F. Dishchekenian, T.C.J. Mertens, D.K. Ninaber, A. Van Der Linden, C. Taube, P.S. Hiemstra, Leiden, Netherlands, p.A5796 Smoking Increases Bacterial Growth and Biofilm Formation/L.G. Vargas Buonfiglio, J.A. Borcherding, R. Fernandez-Ruiz, M. Cano, L. Powers, A.K. Gerke, A.P. Comellas, Iowa City, IA, p.A5797 Water Pipe Condense (WPC) Regulates the Expression of TLRs on Human Macrophages Via Reactive Oxygen Species/E. Mortaz, G.F. Folkerts, J. Garssen, A.K. Kiani, H.R. Jamaati, M. El-Sabbana, A.A. Velayati, I.M. Adcock, Tehran, Iran, p.A5798 Neutrophil Death in a Population of Patients with Neutrophilic COPD/J.L. Cane, K. Hambleton, C. Borg, C. Connolly, T. Powell, L. Xue, I. Pavord, M. Bafadhel, Oxford, United Kingdom, p.A5799 Effect of Inhaled Anticholinergics on Pathogenicity of Pseudomonas Aeruginosa and Staphylococcus Aureus/A. Vyas, J. Joshua, L.E. Crotty Alexander, San Diego, CA, p.A5800 Effects of the Novel Pharmacological Compound Sul-121 on LPS-Induced Airway Neutrophilia/B. Han, W.J. Poppinga, H. Zuo, P. Vogelaar, K. Van Der Graaf, A.J. Halayko, H. Meurs, M. Schmidt, Groningen, Netherlands, p.A5801 ATS 2016 • San Francisco
TUESDAY • MAY 17 297 P1295 P1296 P1297 P1298 P1299 P1300 Alpha-1 Antitrypsin Decreases Pro-Inflammatory Monocyte-Endothelial Cells Interactions Via Fractalkine Axis/A.M. Mikosz, R.K. Maasa, S. Winfree, M. Justice, K. Dunn, I. Petrache, K.A. Serban, Denver, CO, p.A5802 Differences in COPD Blood Monocyte Populations Do Not Affect Maturation to Mature Tissue Macrophage by Ex-Vivo GMCSF/V. Kraskovsky, M. Smith, S. Sethi, K.A. Provost, Buffalo, NY, p.A5803 Increased Neutrophil Gelatinase-Associated Lipocalin (NGAL) Promotes Airway Remodeling in COPD/X. Yao, Y. Wang, I. Adcock, P.J. Barnes, Nanjing, China, p.A5804 Involvement of IL-17A in Development of Airway Fibrosis in Mice/H. Yanagisawa, M. Hashimoto, S. Minagawa, J. Araya, A. Bondesson, A. Budelsky, S. Nishimura, Tokyo, Japan, p.A5805 Characterization of Pulmonary Immunophenotype in Patients with COPD/N.M. Mark, J.K. Kargl, S. Pipavath, A.M. Houghton, Seattle, WA, p.A5806 Langerhans Cells Are Highly and Widely Distributed in Respiratory Bronchiolitis with Smoking-Related Changes of the Lungs in Smokers/A. Masunaga, T. Takemura, E. Yamaguchi, Y. Horio, S. Saeki, T. Mori, M. Suzuki, H. Kohrogi, Kumamoto City, Japan, p.A5807 P1306 P1307 P1308 P1309 P1310 Krypton and Xenon Gas Imaging Using Third Generation Dual Energy CT (DECT) Scan Technologies and an Anthropomorphic Test Object/J.D. Newell, Jr, J. Guo, K.-S. Chan, M. Fuld, J.C. Sieren, W. Kearney, E.A. Hoffman, Iowa City, IA, p.A5812 Third Generation Dual Source CT Scanner and Iterative Reconstruction Software Enables Improved Spatial Resolution of Airway Geometry using a 1024 x 1024 CT Reconstruction Matrix/J.D. Newell, Jr, J. Guo, K.-S. Chan, M.K. Fuld, P.K. Saha, D. Jin, E.A. Hoffman, Iowa City, IA, p.A5813 Parenchymal Airspace Profiling Provides an Unbiased Categorization of Parenchymal Compartments and Accurate Quantification of Parenchymal Destruction/R. Xiao, T. Shiomi, M. Goldklang, J. D’Armiento, New York, NY, p.A5814 Investigating the Nature of Small Airways Disease in Mild/Moderate COPD: Micro-CT Analysis of Paraffin Embedded Lung Tissue/H.-K. Koo, D.M. Vasilescu, S. Booth, A.E. Scott, O. Katsamenis, J. Warner, I. Sinclair, J.C. Hogg, T.-L. Hackett, Vancouver, Canada, p.A5815 A Multi-Variable Assessment of Factors Effecting Dual Energy Computed Tomography Assessment of Pulmonary Perfused Blood Volume-Associated Metrics/T.M. Dougherty, M.K. Han, J.D. Newell, Jr, E. Kazerooni, M. Shirk, N.N. Hansel, R.G. Barr, E.A. Hoffman, Iowa City, IA, p.A5816 C69 THEMATIC POSTER SESSION HERE’S LOOKING AT YOU: IMAGING STUDIES IN COPD 9:00 a.m. - 4:15 p.m. MOSCONE CENTER Viewing: Posters will be on display for entire session. Area L, Hall D (North Building, Lower Level) Discussion: 11:00-11:45: authors will be present for individual discussion 11:45-12:45: authors will be present for discussion with assigned facilitators P1302 P1303 P1304 P1305 Computational Fluid Dynamics Simulation of Airflow and Gaseous Diffusion in Emphysematous Lung Parenchyma/A. Dutta, D.M. Vasilescu, J.C. Hogg, A.B. Phillion, J. Brinkerhoff, Kelowna, Canada, p.A5808 A MiroCT Based Quantitative Assessment of Preterminal Bronchioles in COPD/N. Tanabe, D.M. Vasilescu, J.E. McDonough, D. Kinose, M. Suzuki, J.D. Cooper, J.C. Hogg, Vancouver, Canada, p.A5809 Dose Modulation in an Anthropomorphic Chest Phantom and Its Relative Effects on Regional CT Densitometry Using QCT Analysis/J.A. Schirm, E. Stanton, C. Ibsen, J. Tschirren, J.D. Newell, E.A. Hoffman, K.-S. Chan, J.P. Sieren, Coralville, IA, p.A5810 In-Silico Assessment of Airway Deposition Using Functional Respiratory Imaging for Mono, Dual and Triple Combination Co-Suspension Metered Dose Inhaler Formulations/W. Vos, J. De Backer, J. Schroeder, M. Sommerville, S.K. Dwivedi, W. De Backer, Kontich, Belgium, p.A5811 P1311 P1312 P1313 P1314 P1315 P1316 Fissure Integrity and Rate of Emphysema Progression: SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS)/T.M. Dougherty, J.D. Newell, Jr, Y. Yin, J.A. Schirm, J.P. Sieren, R.G. Barr, E. Bleecker, R.P. Bowler, A.P. Comellas, C.B. Cooper, G.J. Criner, M.T. Dransfield, N.N. Hansel, M.K. Han, R. Kanner, S.C. Lazarus, F.J. Martinez, P.G. Woodruff, K.-S. Chan, E.A, Hoffman, Iowa City, IA p.A5817 Relative Contributions of Quantitative CT Measures to Airflow Obstruction in Cigarette Smokers/J.P. Charbonnier, D.A. Lynch, S.M. Humphries, M. Strand, E.M. Van Rikxoort, Nijmegen, Netherlands, p.A5818 Progression of CT Quantified Lung Density in the COPDGene Study and Its Relationship to Spirometry/E.M. Van Rikxoort, M. Strand, S.M. Humphries, D.A. Lynch, Nijmegen, Netherlands, p.A5819 In Vivo Imaging of Polymers in a1-Antitrypsin Deficiency/I. Haq, D.A. Lomas, London, United Kingdom, p.A5820 Exploration of Vascular Role in COPD Etiology: Standardization and Validation of Regional Pulmonary Arterial Cross Sectional Area Measures from CT/D. Jin, T.M. Dougherty, J. Guo, E.A. Hoffman, J.D. Newell, Jr, P.K. Saha, Iowa City, IA, p.A5821 In Vivo Imaging of Pathogenic Processes in a Rabbit Model of Emphysema/M.P. Goldklang, Y. Tekabe, T. Zelonina, J. Trischler, R. Xiao, K. Stearns, A. Romanov, T. Shiomi, L. Johnson, J. D’Armiento, New York, NY, p.A5822 TUESDAY MORNING ATS 2016 • San Francisco
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American Thoracic Society Internati
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TABLE OF CONTENTS ATS 2016 INTERNAT
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2 FRIDAY • MAY 13 PG2A CLINICAL P
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4 FRIDAY • MAY 13 Target Audience
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6 FRIDAY • MAY 13 11:15 Case Disc
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8 FRIDAY • MAY 13 Chairing: H.B.
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10 FRIDAY • MAY 13 10:25 Advanced
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12 FRIDAY • MAY 13 Objectives At
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14 SATURDAY • MAY 14 Abdominal Ul
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16 SATURDAY • MAY 14 PG17 BASIC
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18 SATURDAY • MAY 14 1:05 In What
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20 SATURDAY • MAY 14 10:30 Practi
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22 SATURDAY • MAY 14 Objectives A
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24 SATURDAY • MAY 14 10:10 Is My
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26 SUNDAY • MAY 15 Chairing: D.M.
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28 SUNDAY • MAY 15 Chronic Cough:
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30 SUNDAY • MAY 15 • understand
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32 SUNDAY • MAY 15 Target Audienc
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34 SUNDAY • MAY 15 Oral Presentat
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36 SUNDAY • MAY 15 9:15 Hyperpola
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38 SUNDAY • MAY 15 310 A Smartpho
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40 SUNDAY • MAY 15 103 Immunosupp
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42 SUNDAY • MAY 15 A26 POSTER DIS
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44 SUNDAY • MAY 15 822 Incidence
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46 SUNDAY • MAY 15 519 Maternal H
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48 SUNDAY • MAY 15 P14 P15 P16 P1
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50 SUNDAY • MAY 15 P1545 P1546 Fa
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52 SUNDAY • MAY 15 P60 P61 Facili
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54 SUNDAY • MAY 15 P149 P150 Faci
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56 SUNDAY • MAY 15 P749 P750 P751
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58 SUNDAY • MAY 15 Facilitator: P
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60 SUNDAY • MAY 15 P1243 P1244 P1
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62 SUNDAY • MAY 15 P1295 P1296 P1
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64 SUNDAY • MAY 15 P1358 P1359 P1
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66 SUNDAY • MAY 15 P91 Facilitato
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68 SUNDAY • MAY 15 P616 P617 P618
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70 SUNDAY • MAY 15 P914 P915 P916
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72 SUNDAY • MAY 15 P556 P557 P558
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74 SUNDAY • MAY 15 Facilitators:
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76 SUNDAY • MAY 15 P997 P998 P999
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78 SUNDAY • MAY 15 P256 P257 P258
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80 SUNDAY • MAY 15 A61 THEMATIC P
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82 SUNDAY • MAY 15 P824 Facilitat
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84 SUNDAY • MAY 15 P1055 P1056 P1
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86 SUNDAY • MAY 15 P1101 P1102 P1
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88 SUNDAY • MAY 15 P1423 P1424 P1
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92 SUNDAY • MAY 15 P377 P378 P379
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94 SUNDAY • MAY 15 P281 P282 P283
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96 SUNDAY • MAY 15 P450 P451 A74
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98 SUNDAY • MAY 15 P1562 P1563 P1
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100 SUNDAY • MAY 15 A80-A THEMATI
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102 SUNDAY • MAY 15 Facilitator:
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104 SUNDAY • MAY 15 11:00 a.m.-12
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106 SUNDAY • MAY 15 L1 U.S. FOOD
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108 SUNDAY • MAY 15 12:15 Post-Pr
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110 SUNDAY • MAY 15 MP406 MP407 M
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112 SUNDAY • MAY 15 clinician and
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114 SUNDAY • MAY 15 A86 BASIC •
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116 SUNDAY • MAY 15 Chairing: M.J
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118 SUNDAY • MAY 15 3:30 High Pre
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120 SUNDAY • MAY 15 102 Toll-Like
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122 SUNDAY • MAY 15 A103 POSTER D
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124 SUNDAY • MAY 15 719 Lactate R
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126 SUNDAY • MAY 15 1014 Determin
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128 SUNDAY • MAY 15 611 Plasma Mi
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130 SUNDAY • MAY 15 412 Daytime S
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132 SUNDAY • MAY 15 6:30 p.m. - 8
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134 MONDAY • MAY 16 SS111 SS112 S
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136 MONDAY • MAY 16 Target Audien
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138 MONDAY • MAY 16 9:40 Empoweri
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140 MONDAY • MAY 16 9:28 Endotoxi
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142 MONDAY • MAY 16 10:15 Adaptiv
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144 MONDAY • MAY 16 Oral Presenta
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146 MONDAY • MAY 16 624 Neonatal
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148 MONDAY • MAY 16 118 Compariso
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150 MONDAY • MAY 16 912 Should Pa
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152 MONDAY • MAY 16 1015 Resverat
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154 MONDAY • MAY 16 718 Health Re
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156 MONDAY • MAY 16 P152 Facilita
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158 MONDAY • MAY 16 B35 THEMATIC
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160 MONDAY • MAY 16 P252 P253 P25
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162 MONDAY • MAY 16 P406 P407 P40
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164 MONDAY • MAY 16 P320 Bilatera
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166 MONDAY • MAY 16 B40 THEMATIC
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168 MONDAY • MAY 16 P528 P529 Fac
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170 MONDAY • MAY 16 Facilitator:
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172 MONDAY • MAY 16 B44 THEMATIC
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174 MONDAY • MAY 16 P484 P485 P48
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176 MONDAY • MAY 16 P1161 P1162 P
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178 MONDAY • MAY 16 B48 THEMATIC
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180 MONDAY • MAY 16 P1238 P1239 P
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182 MONDAY • MAY 16 P1297 P1298 P
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184 MONDAY • MAY 16 Facilitator:
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186 MONDAY • MAY 16 P15 P16 P17 P
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188 MONDAY • MAY 16 Facilitator:
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190 MONDAY • MAY 16 P114 P115 P11
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192 MONDAY • MAY 16 P1408 Enhance
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194 MONDAY • MAY 16 P1455 P1456 P
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196 MONDAY • MAY 16 P1487 P1488 P
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198 MONDAY • MAY 16 P1514 P1515 P
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200 MONDAY • MAY 16 Facilitator:
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202 MONDAY • MAY 16 P559 P560 P56
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204 MONDAY • MAY 16 WS3 CLINICAL
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206 MONDAY • MAY 16 Satellite ear
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208 MONDAY • MAY 16 Objectives At
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210 MONDAY • MAY 16 encourage tra
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212 MONDAY • MAY 16 B82 BEHAVIORA
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214 MONDAY • MAY 16 B86 BASIC •
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216 MONDAY • MAY 16 and a number
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218 MONDAY • MAY 16 2:30 Mortalit
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220 MONDAY • MAY 16 3:00 Simultan
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222 MONDAY • MAY 16 525 Clinical
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224 MONDAY • MAY 16 320 Sensitivi
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226 MONDAY • MAY 16 113 COPD Subt
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228 MONDAY • MAY 16 1004 Health C
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230 MONDAY • MAY 16 609 Skeletal
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232 MONDAY • MAY 16 5:00 p.m. - 7
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234 TUESDAY • MAY 17 Chairing: D.
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236 TUESDAY • MAY 17 CLINICAL YEA
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238 TUESDAY • MAY 17 This session
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240 TUESDAY • MAY 17 bronchiectas
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242 TUESDAY • MAY 17 Target Audie
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244 TUESDAY • MAY 17 C18 MINI SYM
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346 WEDNESDAY • MAY 18 419 A Nove
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348 WEDNESDAY • MAY 18 216 Simpli
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350 WEDNESDAY • MAY 18 815 Multip
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352 WEDNESDAY • MAY 18 D28 POSTER
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354 WEDNESDAY • MAY 18 720 Repeat
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356 WEDNESDAY • MAY 18 P389 Facil
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358 WEDNESDAY • MAY 18 P439 P440
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360 WEDNESDAY • MAY 18 P10 P11 P1
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362 WEDNESDAY • MAY 18 P52 P53 Fa
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364 WEDNESDAY • MAY 18 P95 P96 P9
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366 WEDNESDAY • MAY 18 P698 P699
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368 WEDNESDAY • MAY 18 D42 THEMAT
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370 WEDNESDAY • MAY 18 P748 Funge
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372 WEDNESDAY • MAY 18 P353 P354
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374 WEDNESDAY • MAY 18 P172 P173
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376 WEDNESDAY • MAY 18 P808 Facil
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378 WEDNESDAY • MAY 18 P526 P527
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380 WEDNESDAY • MAY 18 P579 P580
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382 WEDNESDAY • MAY 18 P944 P945
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384 WEDNESDAY • MAY 18 P991 P992
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386 WEDNESDAY • MAY 18 P1036 P103
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388 WEDNESDAY • MAY 18 P1062 P106
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390 WEDNESDAY • MAY 18 11:45 Intr
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392 WEDNESDAY • MAY 18 12:15 Upda
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394 WEDNESDAY • MAY 18 This sessi
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