Final Program

WEDNESDAY • MAY 18 401
D94
MINI SYMPOSIUM
NON-TUBERCULOUS MYCOBACTERIA: ORGANISM
AND HOST
1:30 p.m. - 3:30 p.m. MOSCONE CENTER
Chairing: K.P. Fennelly, MD, MPH, Rockville, MD
D.E. Griffith, MD, Tyler, TX
C. Andrejak, MD, PhD, Amiens, France
R. Thomson, MBBS, PhD, Brisbane, Australia
Oral Presentations
Room 3020/3022 (West Building, Level 3)
1:30 Establishment of the Novel Mouse Models of Human Lung
Nontuberculous Mycobacterial Infections/T. Isobe, C. Sano, R.
Tanino, Y. Tatano, Y. Mori, M. Nakao, Y. Amano, T. Hotta, M.
Hamaguchi, T. Okimoto, Y. Tsubata, S. Hamaguchi, H. Takeyama,
Izumo, Japan, p.A7496
1:45 Evaluation of the Airway Microbiome in Non-Tuberculous
Mycobacteria/B.D. Scaglione, B.G. Wu, Y. Li, K. Alter, J. Gilani, A.
Wang, D. Kamelhar, D. Addrizzo-Harris, L. Segal, New York, NY,
p.A7497
2:00 Nitric Oxide Is a Potential Antimicrobial Against Slow- and
Fast-Growing Mycobacteria/C. Miller, B. McMullin, C. Deppisch,
J. Riethmuller, Vancouver, Canada, p.A7498
2:15 Interleukin 23 / Interleukin 17 Axis Activated by Mycobacterium
Avium Complex (MAC) Is Attenuated in Patients with
MAC-Lung Disease/C.-C. Shu, J.-Y. Wang, C.-J. Yu, Taipei,
Taiwan, p.A7499
2:30 The Association of Peripheral Blood Mucosal-Associated
Invariant T-Cell Cells in Patients with COPD and NTM/
R.J. Napier, E. Henkle, K.L. Winthrop, D.M. Lewinsohn, Portland,
OR, p.A7500
2:45 Clinical and Environmental Nontuberculous Mycobacteria from
Hawaii Demonstrate Varying Degrees of Virulence/J.R. Honda,
N.A. Hasan, Y. Zhou, E.D. Chan, Aurora, CO, p.A7501
3:00 Risk of Nontuberculous Mycobacterial Lung Disease
Associated with Obstructive Lung Disease in Ontario,
Canada/T.K. Marras, M.A. Campitelli, J.C. Kwong, H. Lu, S.K.
Brode, A. Marchand-Austin, A.S. Gershon, F.B. Jamieson, Toronto,
Canada, p.A7502
3:15 The Risk Of Pulmonary Nontuberculous Mycobacterial Disease
Associated with Inhaled Corticosteroid Use/S.K. Brode, M.A.
Campitelli, J.C. Kwong, H. Lu, A. Marchand-Austin, A.S. Gershon,
F.B. Jamieson, T.K. Marras, Toronto, Canada, p.A7503
D95
MINI SYMPOSIUM
DARKNESS ON THE EDGE OF TOWN: NEW
MOLECULAR PATHWAYS IN PULMONARY
HYPERTENSION
1:30 p.m. - 3:30 p.m. MOSCONE CENTER
Chairing: E.F. Spiekerkoetter, MD, Palo Alto, CA
B.B. Graham, MD, Aurora, CO
Oral Presentations
Room 3010/3012 (West Building, Level 3)
1:30 Bone Marrow Endothelial Progenitor Cells Are the Cellular
Mediators of Pulmonary Hypertension in the Murine
Monocrotaline Injury Model/J. Aliotta, M. Pereira, S. Wen, M.S.
Dooner, M. Del Tatto, E. Papa, Y. Cheng, L. Goldberg, P.J.
Quesenberry, J. Klinger, Providence, RI, p.A7504
1:45 The Activation of Wnt5a-ROR2 Axis Enhances
Endothelial-Pericyte Interaction During Pulmonary
Angiogenesis/K. Yuan, M. Orcholski, M. Discipulo, D. Sriram, V.
De Jesus Perez, Palo Alto, CA, p.A7505
2:00 HIPPO-Integrin Linked Kinase Crosstalk Regulates Pulmonary
Vascular Smooth Muscle Cell Proliferation and Survival in
Pulmonary Hypertension/T.V. Kudryashova, D.A. Goncharov, A.
Pena, N. Kelly, R.R. Vanderpool, J. Jeff Baust, A. Kobir, W.
Shufesky, A.E. Morelli, J. Zhao, K. Ihida-Stansbury, H. DeLisser, R.
Tuder, S.M. Kawut, H.H.W. Sillje, S.D. Shapiro, Y. Zhao, E.A.
Goncharova, Pittsburgh, PA, p.A7506
2:15 Estrogen Contributes to the Pathogenesis of Experimental
Pulmonary Hypertension in Obese Male Mice/K.M. Mair, M.
Nilsen, L. Loughlin, M. MacLean, Glasgow, United Kingdom,
p.A7507
2:30 Platelet Bioenergetic Screen Reveals Increased Glycolytic Rate
in Group 1 Pulmonary Hypertension and Increased Oxygen
Consumption in Group 2 Pulmonary Hypertension/Q. Nguyen,
C. Corey, M. Reynolds, P. White, R.R. Vanderpool, M.T. Gladwin,
M.A. Simon, S. Shiva, Pittsburgh, PA, p.A7508
2:45 HIF2a Deletion in the Pulmonary Endothelial Prevents
Hypoxia-Induced Pulmonary Hypertension/A.S. Cowburn, A.
Crosby, D. Macias-Gutierrez, M. Southwood, L. Crotty-Alexander,
N.W. Morrell, E.R. Chilvers, R.S. Johnson, Cambridge, United
Kingdom, p.A7509
3:00 Thrombospondin-1 Deficient Bone Marrow and
Pharmacological Inhibition of TGF-b1 Activation Protects
Against Schistosomiasis Pulmonary Hypertension/R. Kumar, C.
Mickael, B. Kassa, L. Gebreab, D. Koyanangi, L. Sanders, R.
Tuder, B.B. Graham, Aurora, CO, p.A7510
3:15 Dasatinib Causes Pulmonary Endothelial Damage and
Aggravates Pulmonary Hypertension/C. Phan, A. Huertas, A.
Seferian, L. Tu, R. Thuillet, C. Sattler, E.-M. Jutant, M. Le Hiress,
Y. Tamura, M.-C. Chaumais, S. Bouchet, B. Maneglier, M.
Molimard, P. Rousselot, O. Sitbon, G. Simonneau, D. Montani, M.
Humbert, C. Guignabert, Le Plessis-Robins, p.A7511
ATS 2016 • San Francisco
WEDNESDAY AFTERNOON