Final Program

220 MONDAY • MAY 16
3:00 Simultaneous 2-Photon Imaging of Ca2+ Signaling in Airway
Smooth Muscle Cells, T-Cells and Mast Cells in Precision-Cut
Lung Slices from a House Dust Mite Allergic Mouse Model/J.
Chen, J.F. Perez-Zoghbi, M.J. Sanderson, Worcester, MA, p.A4316
3:15 SOCS1 and SOC3 Modulate Immune Response in the Airway
Smooth Muscle/B.E. Himes, C. Koziol-White, M. Johnson, W.
Jester, R.A. Panettieri, Jr., Philadelphia, PA, p.A4317
3:30 Free Fatty Acid 4/GPR120 Receptor Agonist TUG891 - a Novel
Potent Bronchodilator of Small Airways/J.E. Bourke, J. Chen, M.
Simoons, J. Micallef, M. Lam, B. Shimpukade, T. Ulven, M.J.
Sanderson, C. Donovan, Clayton, Australia, p.A4318
3:45 Neutrophil Elastase Promotes the Activation of Signaling
Pathways that Mediate the Inflammatory Phenotype in Airway
Smooth Muscle/A.D. Lockett, S.J. Gunst, Indianapolis, IN, p.A4319
4:00 Deep Inspiration, Fluidization and the Actin Binding Protein
Cofilin/B. Lan, C.Y. Park, K. Jae Hun, R. Krishnan, J.J. Fredberg,
Boston, MA, p.A4320
B99
MINI SYMPOSIUM
THE BEST OF EVERYTHING: HOT TOPICS IN
SLEEP
2:15 p.m. - 4:15 p.m. MOSCONE CENTER
Chairing: M. Teodorescu, MD, MS, Madison, WI
N.A. Antic, MBBS, PhD, Adelaide, Australia
S.P. Patil, MD, PhD, Baltimore, MD
Oral Presentations
Room 2001/2003 (West Building, Level 2)
2:15 Identifying Obstructive Sleep Apnea Patients Vulnerable to
Opioid-Induced Respiratory Depression - A Randomized
Double-Blind Placebo-Controlled Crossover Trial/D. Wang, L.
Rowsell, K. Wong, B. Yee, D.J. Eckert, A. Somogyi, J. Duffin, R.
Grunstein, Camperdown, Australia, p.A4321
2:30 Transgenic Approach to Selectively Modulate Hypoglossal
Motoneurons/T.A. Fleury Curado, H. Pho, L.U. Sennes, A.R.
Schwartz, V.Y. Polotsky, Baltimore, MD, p.A4322
2:45 Relationship Between Sleep-Disordered Breathing and
Aggressiveness Markers of Malignant Cutaneous Melanoma. A
Multicentric Study/M.A. Martinez-Garcia, A. Martorell, E. Nagore,
J.L. Rodriguez-Peralto, M. Sanchez De La Torre, L. Hernandez, J.
Diaz De Atauri, E. Chiner, J.M. Montserrat, R. Farre, F.
Campos-Rodriguez, J. Abad, O. Mediano, F.-B. Illa, V. Cabriada, J.
Corral, I. Cano, F. Troncoso-Acevedo, A. Fortuna, M. De La Pena,
M. Somoza-Gonzalez, M. Gonzalez, M. LLombart, F. Del Campo,
C. Navarro, M.J. Selma, A. Munoz, Valencia, Spain, p.A4323
3:00 Genetic Associations with Obstructive Sleep Apnea Traits in
Hispanic/Latino Americans/B.E. Cade, H. Chen, A.M. Stilp, K.J.
Gleason, T. Sofer, R. Arens, G.I. Bell, J.E. Below, A.C. Bjonnes,
S.G. Chun, M.P. Conomos, W.C. Johnson, A.C. Frazier-Wood, J.M.
Lane, E.K. Larkin, J.S. Loredo, W.S. Post, A.R. Ramos, K. Rice,
J.I. Rotter, N.A. Shah, K.D. Taylor, T.A. Thornton, C. Wang, P.C.
Zee, C.L. Hanis, S.R. Sunyaev, S.R. Patel, C.C. Laurie, X. Zhu, R.
Saxena, X. Lin, S. Redline, Boston, MA, p.A4324
3:15 Sleep-Disordered Breathing Severity and Cognitive
Performance in Community Young School-Aged Children/L.
Kheirandish-Gozal, S.J. Hunter, D.L. Smith, M.F. Philby, J.
Kaylegian, D. Gozal, Chicago, IL, p.A4325
3:30 Effects of Nox2 Activity on Murine Gut Microbiota Alterations
Induced by Sleep Fragmentation and Intermittent Hypoxia/V.
Poroyko, Z. Qiao, A. Khalyfa, A. Gileles-Hillel, R. Farre, D. Gozal,
Chicago, IL, p.A4326
3:45 Mortality Patterns in a Large Series of Patients with
Obstructive Sleep Apnea on Treatment with Continuous
Positive Airway Pressure/J. Valls, G. Castella, R. Boix, C. Colls,
A. Garcia-Altes, I. Teixido, J. Mateo, F. Solsona, J. Escarrabill, M.
Sanchez De La Torre, F. Barbé, Lleida, Spain, p.A4327
4:00 Obstructive Sleep Apnea and Cardiovascular Events After
Percutaneous Coronary Intervention/C.-H. Lee, R. Sethi, R. Li,
H.-H. Ho, T. Hein, M.-H. Jim, G. Loo, C.-Y. Koo, X.-F. Gao, S.
Chandra, X.-X. Yang, S.F. Furlan, Z. Ge, A. Mundhekar, W.-W.
Zhang, C.H.G. Uchoa, R.B. Kharwar, P.-F. Chan, S.-L. Chen, M.Y.
Chan, A.M. Richards, H.-C. Tan, T.-H. Ong, G. Roldan, B.-C. Tai,
L.F. Drager, J.-J. Zhang, Singapore, Singapore, p.A4328
B101
POSTER DISCUSSION SESSION
PHENOTYPING OF ASTHMA IN THE ERA OF
BIOMARKERS AND OMICS
2:15 p.m. - 4:15 p.m. MOSCONE CENTER
Room 2014 (West Building, Level 2)
Poster Viewing 2:15-3:00
Discussion 3:00-4:15
Chairing: A.N. Gerber, MD, PhD, Denver, CO
C. Taube, MD, Leiden, Netherlands
G.M. Gauvreau, PhD, Hamilton, Canada
501 Longitudinal Replication of Severe Asthma Exhaled Breath
Phenotypes by the U-BIOPRED Electronic Nose Platform/
P. Brinkman, A.H. Wagener, P.-P. Hekking, A.T. Bansal, Y. Wang, H.
Weda, H.H. Knobel, T.J. Vink, N.J. Rattray, A. D'Amico, G. Pennazza,
M. Santonico, P.S. Bakke, M. Caruso, K.F. Chung, J. Corfield, S.-E.
Dahlen, R. Djukanovic, T. Geiser, I. Horvath, N. Krug, J. Musial, D.E.
Shaw, I. Pandis, T. Sandstrom, A.R. Sousa, P. Montuschi, S.J. Fowler,
P.J. Sterk, Amsterdam, Netherlands, p.A4329
ATS 2016 • San Francisco