Final Program
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204 MONDAY • MAY 16<br />
WS3<br />
CLINICAL<br />
WORKSHOP<br />
CME Credits Available: 1.5<br />
Nursing Contact Hours Available: 1.8<br />
PULMONARY REHABILITATION FOR INTERSTITIAL<br />
LUNG DISEASE: OPTIMIZING THE MODEL<br />
Registration Fee: $75.00 (includes box lunch)<br />
Attendance is limited. Pre-registration is required.<br />
Assemblies on Pulmonary Rehabilitation; Clinical Problems; Nursing<br />
11:45 a.m. - 1:15 p.m. MOSCONE CENTER<br />
Room 301 (South Building, Esplanade Level)<br />
Target Audience<br />
Providers of care to people with interstitial lung disease; providers of<br />
pulmonary rehabilitation.<br />
Objectives<br />
At the conclusion of this session, the participant will be able to:<br />
• learn about the state of the science underpinning ILD rehabilitation;<br />
• prescribe effective exercise training for people with ILD;<br />
• gain new strategies for comprehensive rehabilitation in ILD.<br />
This workshop will define the state of the evidence for pulmonary rehabilitation<br />
in interstitial lung disease (ILD) and explore strategies to optimize rehabilitation<br />
outcomes for patients with these diverse and disabling respiratory conditions.<br />
Chairing: A.E. Holland, PhD, Melbourne, Australia<br />
L.P. Cahalin, PhD, Miami, FL<br />
11:45 Rehabilitation for ILD: State of the Evidence<br />
A.E. Holland, PhD, Melbourne, Australia<br />
12:00 Peripheral Muscle in ILD: Does it Matter?<br />
S. Mathur, PhD, PT, Toronto, Canada<br />
12:15 Exercise Training Strategies for ILD: Meeting the Physiological<br />
Challenge<br />
B. Vainshelboim, PhD, Petach Tikva, Israel<br />
12:35 Beyond Exercise Training: What is Comprehensive<br />
Rehabilitation for ILD?<br />
J.J. Swigris, DO, MS, Denver, CO<br />
12:55 Capturing Important Changes: Measurement of Outcomes in<br />
Rehabilitation for ILD<br />
L. Dowman, MAppSc, Heidelberg, Australia<br />
WS4<br />
BASIC • CLINICAL • TRANSLATIONAL<br />
WORKSHOP<br />
CME Credits Available: 1.5<br />
PATIENT-DERIVED MODELS OF HUMAN LUNG<br />
DISEASE: A LAB MEETING<br />
Registration Fee: $75.00 (includes box lunch)<br />
Attendance is limited. Pre-registration is required.<br />
Assemblies on Respiratory Cell and Molecular Biology; Allergy,<br />
Immunology and Inflammation; Clinical Problems; Critical Care;<br />
Environmental, Occupational and Population Health; Microbiology,<br />
Tuberculosis and Pulmonary Infections; Pediatrics; Pulmonary<br />
Circulation; Pulmonary Rehabilitation; Respiratory Structure and<br />
Function; Sleep and Respiratory Neurobiology; Thoracic Oncology<br />
11:45 a.m. - 1:15 p.m. MOSCONE CENTER<br />
Room 302 (South Building, Esplanade Level)<br />
Target Audience<br />
Lung health care providers, scientists and investigators interested or involved<br />
in basic, translational and clinical research related to the pathogenesis,<br />
pathology and clinical aspects of COPD and related human lung diseases,<br />
research and care providers engaged in pulmonary and critical care medicine.<br />
Objectives<br />
At the conclusion of this session, the participant will be able to:<br />
• learn about state of the art in vivo, ex vivo and in vitro patient-derived<br />
models of human lung biology and disease;<br />
• implement patient-derived models to study the pathogenesis, phenotype<br />
and candidate therapies for human lung diseases;<br />
• understand how to translate information derived from patient-derived<br />
models into innovative clinically relevant approaches to study, diagnose,<br />
prevent and treat human lung diseases in a personalized manner<br />
(“precision medicine”).<br />
This workshop will discuss state of the art methods to study chronic human lung<br />
diseases (asthma, cystic fibrosis, COPD, and pulmonary fibrosis) in a<br />
personalized manner by modeling complex interaction between different cell<br />
types and tissue components (epithelial cells, extracellular matrix, fibroblasts,<br />
blood vessels, immune cells etc) using patient-derived human samples. In<br />
addition to talks by leading experts in the field, during this session, participants<br />
will have an opportunity to discuss their own research problems, ideas and<br />
questions with the faculty in a “lab meeting format” and learn how to translate<br />
discoveries derived from studies using patient-derived models into novel<br />
personalized approaches to prevent and treat human lung diseases (targeted<br />
“precision medicine” strategies).<br />
Chairing: R. Shaykhiev, MD, PhD, New York, NY<br />
S.D. Reynolds, PhD, Columbus, OH<br />
D.J. Weiss, MD, PhD, Burlington, VT<br />
11:45 “Personalized” In Vitro and Ex Vivo Models of Human Airway<br />
Disease<br />
S.H. Randell, PhD, Chapel Hill, NC<br />
12:00 Patient-Derived 3D-Models of COPD and Emphysema<br />
M. Konigshoff, MD, PhD, Munich, Germany<br />
12:15 Preclinical Humanized Models of Airway Remodeling in<br />
Asthma<br />
R. Freishtat, MD, MPH, Washington, DC<br />
12:30 Modeling Lung Disease Using iPS Cells: Towards Precision<br />
Medicine<br />
D.N. Kotton, MD, Boston, MA<br />
12:45 “Lab Meeting” Discussion<br />
Z. Borok, MD, Los Angeles, CA<br />
C. Coraux, PhD, Reims, France<br />
ATS 2016 • San Francisco