Final Program
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258 TUESDAY • MAY 17<br />
Facilitator:<br />
P175<br />
P176<br />
P177<br />
P178<br />
P179<br />
P180<br />
C35<br />
P. Burkett, MD, PhD, Boston, MA<br />
Levels of Surfactant Protein D in Bronchial Aspirates Within<br />
Six Hours of Lung Transplantation Are Associated with<br />
Clinical Outcomes/J. Madsen, S. Rideout, L. Thakuria, R.<br />
Romano, A. Simon, A. Popov, F. De Robertis, S. Soresi, M. Carby,<br />
A. Reed, N. Marczin, H. Clark, M. Griffiths, Southampton, United<br />
Kingdom, p.A4887<br />
Prospective Molecular Profiling In Human Lung Allografts/F.<br />
Laenger, N. Izykowski, J. Rische, P. Braubach, J. Gottlieb, T.<br />
Welte, A. Haverich, G. Warnecke, H. Kreipe, M.P. Kuehnel, D.<br />
Jonigk, Hannover, Germany, p.A4888<br />
Ischemia Reperfusion-Induced Genetic Expression Profiles in<br />
the Human Lung/B.S. Kim, L. Johnston, J.T. Magruder, J.C.<br />
Grimm, C. Talbot, R.S. Stephens, M. Damarla, R.L. Damico, P.M.<br />
Hassoun, A.S. Shah, Baltimore, MD, p.A4889<br />
Retention and Activation of Donor Vascular Monocytes in<br />
Transplanted Lungs Suggests a Central Role in Primary Graft<br />
Dysfunction/K.C. Tatham, K.P. O’Dea, R. Romano, H. Donaldson,<br />
L. Thakuria, K. Wakabayashi, B.V. Patel, A. Reed, A. Simon, N.<br />
Marczin, M. Takata, London, United Kingdom, p.A4890<br />
Remodelling-Related Molecular Profiles in Different Subforms<br />
of Chronic Lung Allograft Dysfunction/D. Jonigk, B. Rath, L.<br />
Maegel, H. Golpon, N. Izykowski, T. Welte, S. Janciauskene, J.<br />
Gottlieb, G. Warnecke, A. Haverich, H. Kreipe, M.P. Kuehnel, F.<br />
Laenger, Hannover, Germany, p.A4891<br />
Coordinated Immune Activation by Distinct Mononuclear<br />
Phagocytes Subtypes Against the Mismatch of Minor<br />
Antigens/C. Jakubzick, S. Atif, S. Gibbings, R. Gill, T. Grazia, R.<br />
Torres, P.M. Henson, G. Randolph, Denver, CO, p.A7871<br />
THEMATIC POSTER SESSION<br />
INNATE IMMUNE MECHANISMS IN COPD<br />
9:00 a.m. - 4:15 p.m. MOSCONE CENTER<br />
Viewing: Posters will be on display for entire session.<br />
Area L, Hall D (North Building, Lower Level)<br />
Discussion: 11:00-11:45: authors will be present for individual discussion<br />
11:45-12:45: authors will be present for discussion with assigned facilitators<br />
Facilitator:<br />
P1219<br />
P1220<br />
S. Garantziotis, MD, Research Triangle Park, NC<br />
Inflammatory Airway Diseases Are Characterized by a<br />
Microenvironment-Induced Sliding of Mast Cells into a<br />
Gradually Increasing Chymase+, CPA3+, and Cathepsin+<br />
Phenotype/P. Siddhuraj, M. Mori, A. Bergqvist, H.-J. Hoffman, L.<br />
Bjermer, J. Erjefalt, Lund, Sweden, p.A4892<br />
Expression and Function of Growth Differentiation Factor-15 in<br />
Cigarette Smoke-Induced Inflammation and COPD/F.M.<br />
Verhamme, L.J. Seys, E.G. De Smet, S. Provoost, D. Elewaut, G.F.<br />
Joos, G.G. Brusselle, K.R. Bracke, Ghent, Belgium, p.A4893<br />
P1221<br />
P1222<br />
P1223<br />
Elevated Levels of BPIFA1 (SPLUNC1) and BPIFB1 (LPLUNC1)<br />
in Lungs of Patients with COPD/E.G. De Smet, L.J. Seys, F.M.<br />
Verhamme, B.M. Vanaudenaerde, G.F. Joos, G.G. Brusselle, C.D.<br />
Bingle, K.R. Bracke, Ghent, Belgium, p.A4894<br />
Inflammation Paradox - A Detailed Analysis of Inflammatory<br />
Profile in the Large and Small Airway Wall in Mild to Moderate<br />
Chronic Obstructive Pulmonary Disease (COPD) Patients/M.S.<br />
Eapen, K.D. McAlinden, D. Tan, H.K. Muller, S.S. Sohal, E.H.<br />
Walters, Hobart, Australia, p.A4895<br />
The High-Affinity IgE Receptor Is Upregulated on Plasmacytoid<br />
Dendritic Cells in Patients with Severe COPD/P. Stoll, A.<br />
Baehker, M. Ulrich, K. Bratke, K. Garbe, J.C. Virchow, M.<br />
Lommatzsch, Rostock, Germany, p.A4896<br />
P1224 Platelets of COPD Patients Are Hyper-Responsive/F. Aleva, Q.<br />
De Mast, K. Van Bragt, P. De Groot, Y. Heijdra, A. Van Der Ven,<br />
Nijmegen, Netherlands, p.A4897<br />
Facilitator:<br />
P1225<br />
P1226<br />
P1227<br />
P1228<br />
P1229<br />
P1230<br />
Facilitator:<br />
P1231<br />
P1232<br />
M. Divangahi, PhD, Montreal, Canada<br />
Longitudinal Analysis Better Characterized Asthma-COPD<br />
Overlap Syndrome (ACOS): Finding from the Korean Asthma<br />
Cohort, COREA /S.-Y. Park, J. Lee, J.-H. Kim, H.-J. Kim, H.-S. Kwon,<br />
Y.S. Cho, H.-B. Moon, T.-B. Kim, Seoul, Korea, Republic of, p.A4898<br />
Inhibition of p38 MAPK in Human Skeletal Muscle Cells<br />
Attenuates the SAA1 Secretion Initiated by Inflammatory<br />
Stimulation and Could Be Helpful Against Muscle Targeted<br />
Inflammation in COPD/D. Patoine, A. Dube, M.-E. ThAcriault, S.<br />
Bonnet, F. Maltais, Quebec, Canada, p.A4899<br />
Sputum Bacterial and Fungal Dynamics During Exacerbations<br />
of Severe COPD/J. Su, H. Zhou, GuangZhou, China, p.A4900<br />
Highly Selective Inhibitors of PI3Kg for the Oral Treatment of<br />
COPD/K. Karabelas, S. Arlbrandt, P. Bold, A. Butcher, J.F.<br />
Carlsson, P. Cygan, J. Ehnebom, C. Goodyear, L. MacLellan, M.<br />
Nordberg, H. Lindmark, M. Mogemark, R. Pehrson, M. Perry, S.R.<br />
Blomqvist, A. Stern, M. Thomas, Gothenburg, Sweden, p.A4901<br />
Plasma Cytokines and Chemokines Are Associated with<br />
Airflow Obstruction and Exacerbations in The COPDGene<br />
Cohort/E.P. Bradford, S. Jacobson, B.C. Hartman, J. Keene, R.P.<br />
Bowler, Denver, CO, p.A4902<br />
An Impaired Innate Immune Response in Airway Smooth<br />
Muscle Cells from Chronic Cough Patients/C. Rossios, S.<br />
Pavlidis, D. Gibeon, D. Horowitz, P. Branigan, M. Loza, F.<br />
Baribaud, N. Rao, F. Chung, I.M. Adcock, London, United Kingdom,<br />
p.A4903<br />
R. Shaykhiev, MD, PhD, New York, NY<br />
IL17 Is Increased in Diseased Lung Tissue as Well as During<br />
Respiratory Disease Exacerbations and Increases Airway<br />
Contraction in Normal Human Lung Tissue/D. Mohn, L.<br />
Sherman, K. Miner, C. Vezina, J.A. Johnston, Thousand Oaks, CA,<br />
p.A4904<br />
Complement Therapeutics Ameliorate Cigarette Smoke<br />
Induced Emphysema Development and Progression/S.<br />
Stephenson, A. Kirst, A. Alawieh, J.K. Mulligan, T. Williamson, N.<br />
Reaves, S. Tomlinson, C. Atkinson, Charleston, SC, p.A4905<br />
ATS 2016 • San Francisco