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258 TUESDAY • MAY 17<br />

Facilitator:<br />

P175<br />

P176<br />

P177<br />

P178<br />

P179<br />

P180<br />

C35<br />

P. Burkett, MD, PhD, Boston, MA<br />

Levels of Surfactant Protein D in Bronchial Aspirates Within<br />

Six Hours of Lung Transplantation Are Associated with<br />

Clinical Outcomes/J. Madsen, S. Rideout, L. Thakuria, R.<br />

Romano, A. Simon, A. Popov, F. De Robertis, S. Soresi, M. Carby,<br />

A. Reed, N. Marczin, H. Clark, M. Griffiths, Southampton, United<br />

Kingdom, p.A4887<br />

Prospective Molecular Profiling In Human Lung Allografts/F.<br />

Laenger, N. Izykowski, J. Rische, P. Braubach, J. Gottlieb, T.<br />

Welte, A. Haverich, G. Warnecke, H. Kreipe, M.P. Kuehnel, D.<br />

Jonigk, Hannover, Germany, p.A4888<br />

Ischemia Reperfusion-Induced Genetic Expression Profiles in<br />

the Human Lung/B.S. Kim, L. Johnston, J.T. Magruder, J.C.<br />

Grimm, C. Talbot, R.S. Stephens, M. Damarla, R.L. Damico, P.M.<br />

Hassoun, A.S. Shah, Baltimore, MD, p.A4889<br />

Retention and Activation of Donor Vascular Monocytes in<br />

Transplanted Lungs Suggests a Central Role in Primary Graft<br />

Dysfunction/K.C. Tatham, K.P. O’Dea, R. Romano, H. Donaldson,<br />

L. Thakuria, K. Wakabayashi, B.V. Patel, A. Reed, A. Simon, N.<br />

Marczin, M. Takata, London, United Kingdom, p.A4890<br />

Remodelling-Related Molecular Profiles in Different Subforms<br />

of Chronic Lung Allograft Dysfunction/D. Jonigk, B. Rath, L.<br />

Maegel, H. Golpon, N. Izykowski, T. Welte, S. Janciauskene, J.<br />

Gottlieb, G. Warnecke, A. Haverich, H. Kreipe, M.P. Kuehnel, F.<br />

Laenger, Hannover, Germany, p.A4891<br />

Coordinated Immune Activation by Distinct Mononuclear<br />

Phagocytes Subtypes Against the Mismatch of Minor<br />

Antigens/C. Jakubzick, S. Atif, S. Gibbings, R. Gill, T. Grazia, R.<br />

Torres, P.M. Henson, G. Randolph, Denver, CO, p.A7871<br />

THEMATIC POSTER SESSION<br />

INNATE IMMUNE MECHANISMS IN COPD<br />

9:00 a.m. - 4:15 p.m. MOSCONE CENTER<br />

Viewing: Posters will be on display for entire session.<br />

Area L, Hall D (North Building, Lower Level)<br />

Discussion: 11:00-11:45: authors will be present for individual discussion<br />

11:45-12:45: authors will be present for discussion with assigned facilitators<br />

Facilitator:<br />

P1219<br />

P1220<br />

S. Garantziotis, MD, Research Triangle Park, NC<br />

Inflammatory Airway Diseases Are Characterized by a<br />

Microenvironment-Induced Sliding of Mast Cells into a<br />

Gradually Increasing Chymase+, CPA3+, and Cathepsin+<br />

Phenotype/P. Siddhuraj, M. Mori, A. Bergqvist, H.-J. Hoffman, L.<br />

Bjermer, J. Erjefalt, Lund, Sweden, p.A4892<br />

Expression and Function of Growth Differentiation Factor-15 in<br />

Cigarette Smoke-Induced Inflammation and COPD/F.M.<br />

Verhamme, L.J. Seys, E.G. De Smet, S. Provoost, D. Elewaut, G.F.<br />

Joos, G.G. Brusselle, K.R. Bracke, Ghent, Belgium, p.A4893<br />

P1221<br />

P1222<br />

P1223<br />

Elevated Levels of BPIFA1 (SPLUNC1) and BPIFB1 (LPLUNC1)<br />

in Lungs of Patients with COPD/E.G. De Smet, L.J. Seys, F.M.<br />

Verhamme, B.M. Vanaudenaerde, G.F. Joos, G.G. Brusselle, C.D.<br />

Bingle, K.R. Bracke, Ghent, Belgium, p.A4894<br />

Inflammation Paradox - A Detailed Analysis of Inflammatory<br />

Profile in the Large and Small Airway Wall in Mild to Moderate<br />

Chronic Obstructive Pulmonary Disease (COPD) Patients/M.S.<br />

Eapen, K.D. McAlinden, D. Tan, H.K. Muller, S.S. Sohal, E.H.<br />

Walters, Hobart, Australia, p.A4895<br />

The High-Affinity IgE Receptor Is Upregulated on Plasmacytoid<br />

Dendritic Cells in Patients with Severe COPD/P. Stoll, A.<br />

Baehker, M. Ulrich, K. Bratke, K. Garbe, J.C. Virchow, M.<br />

Lommatzsch, Rostock, Germany, p.A4896<br />

P1224 Platelets of COPD Patients Are Hyper-Responsive/F. Aleva, Q.<br />

De Mast, K. Van Bragt, P. De Groot, Y. Heijdra, A. Van Der Ven,<br />

Nijmegen, Netherlands, p.A4897<br />

Facilitator:<br />

P1225<br />

P1226<br />

P1227<br />

P1228<br />

P1229<br />

P1230<br />

Facilitator:<br />

P1231<br />

P1232<br />

M. Divangahi, PhD, Montreal, Canada<br />

Longitudinal Analysis Better Characterized Asthma-COPD<br />

Overlap Syndrome (ACOS): Finding from the Korean Asthma<br />

Cohort, COREA /S.-Y. Park, J. Lee, J.-H. Kim, H.-J. Kim, H.-S. Kwon,<br />

Y.S. Cho, H.-B. Moon, T.-B. Kim, Seoul, Korea, Republic of, p.A4898<br />

Inhibition of p38 MAPK in Human Skeletal Muscle Cells<br />

Attenuates the SAA1 Secretion Initiated by Inflammatory<br />

Stimulation and Could Be Helpful Against Muscle Targeted<br />

Inflammation in COPD/D. Patoine, A. Dube, M.-E. ThAcriault, S.<br />

Bonnet, F. Maltais, Quebec, Canada, p.A4899<br />

Sputum Bacterial and Fungal Dynamics During Exacerbations<br />

of Severe COPD/J. Su, H. Zhou, GuangZhou, China, p.A4900<br />

Highly Selective Inhibitors of PI3Kg for the Oral Treatment of<br />

COPD/K. Karabelas, S. Arlbrandt, P. Bold, A. Butcher, J.F.<br />

Carlsson, P. Cygan, J. Ehnebom, C. Goodyear, L. MacLellan, M.<br />

Nordberg, H. Lindmark, M. Mogemark, R. Pehrson, M. Perry, S.R.<br />

Blomqvist, A. Stern, M. Thomas, Gothenburg, Sweden, p.A4901<br />

Plasma Cytokines and Chemokines Are Associated with<br />

Airflow Obstruction and Exacerbations in The COPDGene<br />

Cohort/E.P. Bradford, S. Jacobson, B.C. Hartman, J. Keene, R.P.<br />

Bowler, Denver, CO, p.A4902<br />

An Impaired Innate Immune Response in Airway Smooth<br />

Muscle Cells from Chronic Cough Patients/C. Rossios, S.<br />

Pavlidis, D. Gibeon, D. Horowitz, P. Branigan, M. Loza, F.<br />

Baribaud, N. Rao, F. Chung, I.M. Adcock, London, United Kingdom,<br />

p.A4903<br />

R. Shaykhiev, MD, PhD, New York, NY<br />

IL17 Is Increased in Diseased Lung Tissue as Well as During<br />

Respiratory Disease Exacerbations and Increases Airway<br />

Contraction in Normal Human Lung Tissue/D. Mohn, L.<br />

Sherman, K. Miner, C. Vezina, J.A. Johnston, Thousand Oaks, CA,<br />

p.A4904<br />

Complement Therapeutics Ameliorate Cigarette Smoke<br />

Induced Emphysema Development and Progression/S.<br />

Stephenson, A. Kirst, A. Alawieh, J.K. Mulligan, T. Williamson, N.<br />

Reaves, S. Tomlinson, C. Atkinson, Charleston, SC, p.A4905<br />

ATS 2016 • San Francisco

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