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144 MONDAY • MAY 16<br />

Oral Presentations<br />

9:00 Does Cardiopulmonary Fitness and Pulmonary Function Differ<br />

Between Age Matched Groups of Children with Primary Ciliary<br />

Dyskinesia (PCD) and Cystic Fibrosis (CF) During One<br />

Year?/A.M. Ring, K. Green, F.F. Buchvald, K.G. Nielsen,<br />

Copenhagen, Denmark, p.A2901<br />

9:15 Novel Technology Demonstrates Apical Release of<br />

S-Nitrosothiols and F508Del CFTR Maturation in Response to<br />

Airflow in the Human Airway Epithelium/J. Seckler, N.<br />

Marozkina, L. Smith, S.J. Lewis, C.U. Cotton, B. Gaston,<br />

Cleveland, OH, p.A2902<br />

9:30 Are Staphylococcus Aureus Infections Causally Related to<br />

More Rapid Disease Progression in Children with Cystic<br />

Fibrosis?/D. Caudri, L. Turkovic, J. Ng, N. De Klerk, T. Rosenow,<br />

G. Hall, S. Ranganathan, S. Stick, Subiaco, Australia, p.A2903<br />

9:45 Sleeping chILD: Neuroendocrine Cell Hyperplasia of Infancy<br />

and Polysomnography/S.M.M. Hawkins, M.E. Kroehl, R.R.<br />

Deterding, D.R. Liptzin, Aurora, CO, p.A2904<br />

10:00 Sex Associated Differences in Gene Expression in Neonates<br />

with BPD/D. Chhabra, C. Espinoza, J. Hagood, San Diego, CA,<br />

p.A2905<br />

10:15 Lung Parenchyma on CT Scans of Premature Infants<br />

Normalizes with Age/D.R. Spielberg, J. Stein, L.L. Walkup, A.<br />

Brody, J.C. Woods, Cincinnati, OH, p.A2906<br />

10:30 Long-Term Respiratory Morbidity in Recipients of Pediatric<br />

Solid Organ Transplants: A Retrospective Review/M.F.A.<br />

Wright, M. Chilvers, T. Blydt-Hansen, Vancouver, Canada, p.A2907<br />

Featured Speaker<br />

10:45 Accidental Career/A.C. Koumbourlis, MD, MPH, Washington, DC<br />

9:30 Genome Wide Association Studies in Chronic<br />

Thromboembolic Pulmonary Hypertension/M. Toshner, M.<br />

Bleda, M. Newnham, I. Lang, M. Delcroix, J. Cannon, K. Sheares,<br />

G. Coghlan, P.A. Corris, S. Gibbs, D. Kiely, A. Peacock, M.<br />

Simpson, R.C. Trembath, M.R. Wilkins, S.J. Wort, C. Ng, J.<br />

Dunning, N. Screaton, S. Tsui, D. Jenkins, S. Graf, J. Pepke-Zaba,<br />

N.W. Morrell, Cambridge, United Kingdom, p.A2910<br />

9:45 Plasma Proteome Analysis in Idiopathic Pulmonary Arterial<br />

Hypertension Identifies a Panel of Prognostic Proteins/C.<br />

Rhodes, J. Wharton, P. Ghataorhe, G. Watson, B. Girerd, L.S.<br />

Howard, S. Gibbs, R. Condliffe, C.A. Elliot, D. Kiely, G. Simonneau,<br />

D. Montani, O. Sitbon, H. Gall, R.T. Schermuly, H.A. Ghofrani, A.<br />

Lawrie, M. Humbert, M. Wilkins, London, United Kingdom, p.A2911<br />

10:00 Whole Exome Sequencing Reveals CES1 as a Novel Gene in<br />

Methamphetamine Induced Pulmonary Arterial Hypertension/V.<br />

De Jesus Perez, M. Orcholski, A. Khurshudyan, K. Yuan, R.T.<br />

Zamanian, Palo Alto, CA, p.A2912<br />

10:15 Genetic Analysis of 1738 WHO Group 1 PAH Patients Enrolled<br />

in the PAH Biobank/M. Pauciulo, K. Lutz, C. Winslow, A.<br />

Walsworth, A. Gygi, M. Barve, A. Reponen, L. Martin, H. He, W.<br />

Nichols, Cincinnati, OH, p.A2913<br />

10:30 Metabonomic Phenotype Analysis in Patients with Pulmonary<br />

Hypertension/P. Ghataorhe, C. Rhodes, J. Wharton, V.<br />

Horneffer-van Der Sluis, B. Jimenez, M. Lewis, J. Pearce, M.<br />

Kyriakides, G. Watson, L.S. Howard, S. Gibbs, H. Gall, H.A.<br />

Ghofrani, R.T. Schermuly, Z. Takats, I. Wilson, J. Nicholson, M.<br />

Wilkins, London, United Kingd, p.A2914<br />

Featured Speaker<br />

10:45 More Data, More Problems/M.W. Geraci, MD, Indianapolis, IN,<br />

B20<br />

MINI SYMPOSIUM<br />

HOOKED ON PH’OMICS<br />

9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />

Chairing: C.E. Ventetuolo, MD, MS, Providence, RI<br />

A.A. Desai, MD, Tucson, AZ<br />

A.R. Hemnes, MD, Nashville, TN<br />

Oral Presentations<br />

Room 3003/3005 (West Building, Level 3)<br />

9:00 Utility of Deep Phenotyping in the Identification and Validation<br />

of Novel Causal Whole Genome Sequencing Variation in<br />

Patients with Pulmonary Arterial Hypertension/C. Hadinnapola,<br />

M. Bleda, M. Haimel, H.J. Bogaard, G. Coghlan, P.A. Corris, J.S.<br />

Gibbs, D.G. Kiely, A. Lawrie, A.J. Peacock, R.D. Machado, J.<br />

Pepke-Zaba, A. Vonk-Noordegraaf, R.C. Trembath, J. Wharton,<br />

M.R. Wilkins, S.J. Wort, S. Graf, N.W. Morrell, Cambr, p.A2908<br />

9:15 Abnormal Transpulmonary Metabolite Flux In Exercise Induced<br />

Pulmonary Arterial Vasculopathy/A.B. Waxman, C. Bennett, A.J.<br />

Janocha, S.A.A. Comhair, S.C. Kalhan, J.A. Leopold, S.C.<br />

Erzurum, D.M. Systrom, Boston, MA, p.A2909<br />

B21<br />

POSTER DISCUSSION SESSION<br />

GENETICS, GENOMICS, AND GENE EXPRESSION<br />

IN ASTHMA AND COPD<br />

9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />

Room 2024 (West Building, Level 2)<br />

Poster Viewing 9:00-9:45<br />

Discussion 9:45-11:00<br />

Chairing: D. Vercelli, MD, Tucson, AZ<br />

C.P. Hersh, MD, MPH, Boston, MA<br />

S. Sharma, MD, MPH, Aurora, CO<br />

601 Whole Blood MicroRNA Biomarkers in Acute Respiratory<br />

Distress Syndrome/Z. Zhu, Y. Wei, L. Su, R. Zhang, P. Tejera, Z.<br />

Wang, Q. Lu, L. Liang, A. Baccarelli, D.C. Christiani, Boston, MA,<br />

p.A2915<br />

602 Quantitative Genetic Analysis of MUC5AC and MUC5B in a<br />

Mouse Model of Asthma/S. Kelada, A. Livraghi-Butrico, K.<br />

McFadden, J. Thomas, W.K. O’Neal, R.C. Boucher, Chapel Hill,<br />

NC, p.A2916<br />

ATS 2016 • San Francisco

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