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120 SUNDAY • MAY 15<br />

102 Toll-Like Receptor Signaling in Human Lung Pericytes/J.P.<br />

Higuero, C.L. Wilson, L.M. Felton, S.E. Stephenson, C.F. Hung, W.A.<br />

Altemeier, J.E. Baatz, L.M. Schnapp, Charleston, SC, p.A2641<br />

103 The RIG-I-Like Receptor Pathway Is Protective During Sterile<br />

Acute Lung Injury/M.P. Mohning, A.L. McCubbrey, K.J. Mould,<br />

P.M. Henson, W. Janssen, Aurora, CO, p.A2642<br />

104 Toll-Like Receptor 5 Modulates MyD88-Dependent Toll-Like<br />

Receptor 4 Signaling/C.G. Johnson, J. Sciurba, A. Rice, J. Aloor,<br />

J. Cyphert, K. Bulek, X. Li, M.B. Fessler, S. Garantziotis, Research<br />

Triangle Park, NC, p.A2643<br />

105 ApoA-I Binding Protein Attenuates Murine ARDS/B.T. Suratt, E.<br />

Burg, N. Ubags, S.-H. Choi, L. Fang, Y. Miller, Burlington, VT,<br />

p.A2644<br />

106 Overexpression of Decay Accelerating Factor Mitigates<br />

Fibrotic Responses to Lung Injury/R. Vittal, A.J. Fisher, E.L.<br />

Thompson, E.A. Mickler, M.R. Vasko, D.S. Wilkes, H. Gu, Ann<br />

Arbor, MI, p.A2645<br />

107 Modulation of TLR3-Stimulated Release of IL-26 by IL-17A and<br />

IL-22 in Bronchial Epithelial Cells/K.F. Che, L. Palmberg, A.<br />

Linden, Stockholm, Sweden, p.A2646<br />

108 Plasminogen Activator Inhibitor-1 (PAI-1) Plays a Critical Role<br />

in Alcohol-Enhanced Acute Lung Injury/L. Poole, V. Massey, E.<br />

Torres-Gonzalez, D. Siow, N. Warner, J. Luyendyk, J.D.<br />

Ritzenthaler, J. Roman, G. Arteel, Louisville, KY, p.A2647<br />

109 Transient Receptor Potential Vanilloid Antagonism Alleviates<br />

the Propagation of Lung Injury/M. Cereda, Y. Xin, S. Kadlecek, J.<br />

Zeng, A. Rodriguez, H. Staroba, N. Meeder, Q. Bey, H. Profka, S.<br />

Siddiqui, M. Pourfathi, H. Hamedani, R.R. Rizi, Philadelphia, PA,<br />

p.A2648<br />

110 Targeting Glutamine Metabolism as a Novel Means to Prevent<br />

LPS-Induced Acute Lung Injury/C.L. Vigeland, Y. Chan-Li, S.L.<br />

Collins, A.H. Hughes, M.-H. Oh, J.D. Powell, M.R. Horton,<br />

Baltimore, MD, p.A2649<br />

111 Orchestrating Role of Apoptosis Inhibitor of Macrophage (AIM)<br />

in Resolution of Acute Lung Injury in Mice/H. Kimura, M. Suzuki,<br />

S. Konno, T. Miyazaki, H. Shindou, M. Nishimura, Sapporo, Japan,<br />

p.A2650<br />

112 Uncoupled Inducible Nitric Oxide Synthase Influences<br />

Macrophage Polarization in Acute Lung Injury/T. Golden, M.<br />

Crabtree, K. Channon, A.J. Gow, Piscataway, NJ, p.A2651<br />

113 1,5-Anhydro-D-Fructose, a Monosaccharide from<br />

Glycogen/Starch, Ameliorates Bleomycin-Induced Lung Injury<br />

by Inhibiting Inflammasome Activation/S. Noma, T. Saitoh, K.-I.<br />

Kawahara, Y. Ito, H. Inoue, I. Maruyama, Kamogawa City, Japan,<br />

p.A2652<br />

114 Deficiency of a7 Nicotinic Acetylcholine Receptor Lessens<br />

Bleomycin-Induced Lung Injury and Fibrosis/X. Su, P. Sun, M.<br />

Pan, C. Zhao, L. Li, Shanghai, China, p.A2653<br />

115 Heme Oxygenase-1 Regulates ROS-ERK1/2 Signaling in<br />

Silica-Induced Lung Injury/K. Nakashima, T. Sato, Y. Shibata, R.<br />

Ushio, M. Ikeda, H. Watanabe, K. Nagai, K. Tashiro, H. Nagakura,<br />

N. Horita, M. Yamamoto, M. Shinkai, M. Kudo, T. Kaneko,<br />

Yokohama, Japan, p.A2654<br />

116 Immune Exhaustion and IL-6/STAT3 Activation in IPF<br />

Lymphocytes/A. Young, G. Shaginurova, J.A. Kropski, T.S.<br />

Blackwell, W. Drake, Nashville, TN, p.A2655<br />

117 The EC-SOD R213G Polymorphism Enhances Recovery of<br />

Bleomycin-Induced Airway Inflammation Mitigating<br />

Subsequent Fibrosis and Pulmonary Hypertension/G.C.<br />

Mouradian, R. Gaurav, J. Maltzahn, J. Varasteh, B.C. Hartman,<br />

R.P. Bowler, E. Grayck, Aurora, CO, p.A2656<br />

118 Circulating Fibrocytes as Biomarkers of Outcome in Acute<br />

Respiratory Distress Syndrome/A. Alrbiaan, M. Burdick, A. Kadl,<br />

K.B. Enfield, B. Mehrad, Charlottesville, VA, p.A2657<br />

119 In Immature Mice, Hyperoxia-Activated CLEC9A+, CD103+<br />

Dendritic Cells Are Sufficient to Confer Exaggerated T Cell<br />

Activation and Type 1 Inflammation/T. Cui, B. Maheshwer, A.P.<br />

Popova, Ann Arbor, MI, p.A2658<br />

120 A Genome-Wide Association Study Identifies Genetic Variation<br />

in MBP that Is Associated with Ventilator-Free Days in Patients<br />

with ARDS in the iSPAAR Consortium/I. Barnett, C.S. Calfee, M.<br />

Matthay, N.J. Meyer, C. Mikacenic, G. O’Keefe, H. Hakonarson,<br />

A.J. Sandford, M. Obeidat, D.S. Postma, D.C. Nickle, Y. Bosse,<br />

G.P. Jarvik, K. Walley, J. Russell, X. Lin, D.C. Christiani, M.M.<br />

Wurfel, Boston, MA, p.A2659<br />

121 Airway Inflammation at Birth and Lung Function at School Age<br />

in Preterm Neonates: A Pilot Study/M. Slaats, M. Al-Nejar, N.<br />

Everaars, E. Wouters, L. Mahieu, E. Oostveen, J. De Dooy, W. De<br />

Backer, S. Verhulst, Edegem, Belgium, p.A2660<br />

122 Regulation of Pseudomonas Aeruginosa Exoprotease and<br />

Elastase Activity by Thrombospondin-1/J. Zupetic, Y. Qu, T.F.<br />

Olonisakin, M. Hulver, Z. Xiong, J. Bomberger, P. Thibodeau, P.<br />

Ray, J.S. Lee, Pittsburgh, PA, p.A2661<br />

123 Circulating Thrombogenic Endothelial Cell-Derived<br />

Microparticles Are Present in Patients with Systemic<br />

Sclerosis/M.J. Scott, S. Osher, M. Hinchcliff, J.E. Dematte, I.<br />

Weiss, M. Cuttica, L. Morales-Nebreda, J. Varga, D. Vaughan, H.C.<br />

Kwaan, G.S. Budinger, G.M. Mutlu, Chicago, IL, p.A2662<br />

124 G-CSF and IL-6 Are Required for Early Post Burn Neutrophilia<br />

and Increased Lung Myeloperoxidase Activity/J.C. Gardner,<br />

J.G. Noel, L. Pitstick, N.M. Nikolaidis, F.X. McCormack, Cincinnati,<br />

OH, p.A2663<br />

125 Genome-Wide Expression Profiling of Acute Respiratory<br />

Distress Syndrome (ARDS)/P. Tejera, R. Zhang, Y. Wei, Z. Zhu,<br />

Z. Wang, L. Su, D.C. Christiani, Boston, MA, p.A2664<br />

A102<br />

POSTER DISCUSSION SESSION<br />

HIGHLIGHTS IN PATIENT-CENTERED RESEARCH:<br />

METHODS AND OUTCOMES<br />

2:15 p.m. - 4:15 p.m. MOSCONE CENTER<br />

Room 309 (South Building, Esplanade Level)<br />

Poster Viewing 2:15-3:00<br />

Discussion 3:00-4:15<br />

ATS 2016 • San Francisco

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