Final Program
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412 WEDNESDAY • MAY 18<br />
404 Intermittent Hypoxia Augments Mesangial Matrix Expansion by<br />
Increasing Glomerular Expression of TGF-b and CTGF<br />
Proteins/B.H. Abuyassin, M. Badran, N. Ayas, I. Laher, Vancouver,<br />
Canada, p.A7725<br />
405 nmMLCK: A Key Player in Intermittent Hypoxia-Induced<br />
Inflammatory Vascular Remodeling?/C. Arnaud, S. Recoquillon,<br />
S. Bouyon, E. Lemarie, S. Cachot, M. Toral, C. Martinez, R.<br />
Andriantsitohaina, J.L. Pepin, Grenoble, France, p.A7726<br />
406 Circulating Plasma Exosomes and CardioMetabolic Function<br />
in Mice Exposed to Long-Term Alternating Dark-Light Cycles<br />
Mimicking Shift Work/A. Khalyfa, Z. Qiao, V. Poroyko, A.<br />
Gileles-Hillel, A.A. Khalyfa, M. Akbarpour, D. Gozal, Chicago, IL,<br />
p.A7727<br />
407 Activation of Integrated Stress Response (ISR) and<br />
Intermittent Hypoxia (IH)-Induced Metabolic Dysfunction in a<br />
Mouse Model of Sleep Apnea/A. Khalyfa, Z. Qiao, A.<br />
Gileles-Hillel, A.A. Khalyfa, M. Akbarpour, B. Popko, B, D. Gozal,<br />
Chicago, IL, p.A7728<br />
408 Activation of Integrated Stress Response (ISR) By Sleep<br />
Fragmentation During Late Gestation (LG-SF) in Mouse Is<br />
Critical to Emergence of Metabolic Phenotype in Adult<br />
Offspring/A. Khalyfa, Z. Qiao, A.A. Khalyfa, A. Gileles-Hillel, M.<br />
Akbarpour, B. Poroyko, D. Gozal, Chicago, IL, p.A7729<br />
409 Endoplasmic Reticulum Stress as a Novel Inducer of Hypoxia<br />
Inducible Factor-1 Activity: Its Role in the Susceptibility to<br />
Myocardial Ischemia-Reperfusion Induced by Chronic<br />
Intermittent Hypoxia/E. Belaidi, A. Thomas, G. Bourdier, S.<br />
Moulin, E. Lemarie, R. Tamisier, P. Levy, J.L. Pepin, I. Korichneva,<br />
D. Godin-Ribuot, C. Arnaud, Grenoble, France, p.A7730<br />
410 High-Intensity Training Reduces Intermittent Hypoxia-Induced<br />
ER Stress and Myocardial Infarct Size/G. Bourdier, P. Flore, H.<br />
Sanchez, J.L. Pepin, E. Belaidi, C. Arnaud, Grenoble, France,<br />
p.A7731<br />
411 NF-kB Pathway Plays a Critical Role in Intermittent Hypoxia<br />
Induced Macrophage Foam Cell Formation/T. Imamura, G.G.<br />
Haddad, La Jolla, CA, p.A7732<br />
412 Endothelial Dysfunction in Diabetic Mice Is Exacerbated by<br />
Chronic Intermittent Hypoxia (CIH)/M. Badran, N. Ayas, I. Laher,<br />
Vancouver, Canada, p.A7733<br />
413 Low Frequency Intermittent Hypoxia Reduces<br />
Endothelium-Dependent Contraction in C57 Mice with<br />
Diet-Induced Obesity/M.Y.K. Lee, J.C.W. Mak, M.S.M. Ip, Hong<br />
Kong, Hong Kong Prc, p.A7734<br />
414 Hepatocyte Knockout of HIF-1a Accentuates Metabolic<br />
Improvement in Sustained Hypoxia/O. Mesarwi, M.-K. Shin, S.<br />
Bevans-Fonti, C.P. O’Donnell, V.Y. Polotsky, Baltimore, MD,<br />
p.A7735<br />
415 Various Degrees of Intensities of Intermittent Hypoxia on<br />
Adipogenesis in Diet-Induced Obese Mouse Model/Y. Wang,<br />
M.Y.K. Lee, J.C.W. Mak, M.S.M. Ip, Hong Kong, Hong Kong Prc,<br />
p.A7736<br />
416 Late Gestational Intermittent Hypoxia Leads to Metabolic and<br />
Epigenomic Alterations in Adult Offspring/R. Cortese, A.<br />
Khalyfa, R. Bao, J. Andrade, D. Gozal, Chicago, IL, p.A7737<br />
417 Role of COX-2 in Intermittent Hypoxia-Induced Tumor Growth<br />
in a Murine Model of Obstructive Sleep Apnea/I. Almendros, N.<br />
Campillo, M. Torres, D. Gozal, J.M. Montserrat, C. Picado, R.<br />
Farre, D. Navajas, Barcelona, Spain, p.A7738<br />
418 Intermitent Hypoxia Increases Tumor Angiogenesis in a<br />
Mouse Model of Heterotropic Kidney Cancer/M. Torres, A.<br />
Vilaseca, N. Campillo, M. Musquera, J.M. Montserrat, A. Alcaraz,<br />
R. Farre, I. Almendros, Barcelona, Spain, p.A7739<br />
419 Progression of Tumor Growth in Intermittent Hypoxia is<br />
Associated with Decreased Number of Granzyme B Expressing<br />
CD8+ T Cell Lymphocytes/M. Akbarpour, A. Khalyfa, Q.<br />
Zhuanhong, A.A. Khalyfa, A. Gileles-Hillel, I. Almendros, R. Farre,<br />
D. Gozal, Chicago, IL, p.A7740<br />
420 Antioxidant Tempol Ameliorates Intermittent Hypoxia-Induced<br />
Melanoma Lung Metastasis in a Mouse Model of OSA/L. Li, M.<br />
Liang, Y. Fang, J. Cao, B. Chen, Tianjin, China, p.A7741<br />
421 A Membrane Progesterone Receptor Agonist Reduces Apnea<br />
Frequency in Newborn Male and Female Rats/N. Uppari, H.<br />
Kouchi, V. Joseph, A. Bairam, Quebec, Canada, p.A7742<br />
422 Severe Chronic Intermittent Hypoxia Could Mask the Severity<br />
of Lung Cancer, in Terms of Plasmatic Tumor Markers/T.<br />
Gallego-Martin, E. Gonzalez-Obeso, E. Olea, S. Yubero, I. Docio,<br />
A. Obeso, Valladolid, Spain, p.A7743<br />
D110<br />
POSTER DISCUSSION SESSION<br />
UNUSUAL TUMORS OF THE CHEST<br />
1:30 p.m. - 3:30 p.m. MOSCONE CENTER<br />
Room 309 (South Building, Esplanade Level)<br />
Poster Viewing 1:30-2:15<br />
Discussion 2:15-3:30<br />
Chairing: D.E. Ost, MD, MPH, Houston, TX<br />
L.T. Tanoue, MD, New Haven, CT<br />
301 Atypical Multifocal Pulmonary Carcinoid Tumor: A Case<br />
Report of a Very Rare Neoplasm/C.A. Celis Preciado, P. Gil, C.<br />
Zuluaga, L. Jaramillo, Bogota, Colombia, p.A7744<br />
302 Bilateral Synchronous Pulmonary Carcinoid Tumors Treated<br />
with Staged Segmentectomy/A. Attili, J. Shaw, Brooklyn, NY,<br />
p.A7745<br />
303 Atypical Large Hydropneumothorax in the Setting of an<br />
Uncommon Lung Neuroendocrine Tumor/J.M. Sosa, L.<br />
Carrasco, F. Hafeez, M. Abdullahi, R. Ayinla, New York, NY,<br />
p.A7746<br />
304 A Rare Case of Mucoepidermoid Carcinoma of the Lung/A.<br />
Rajagopal, A.P. Maskey, Lexington, KY, p.A7747<br />
305 Endobronchial Leiomyoma Presenting with Asthma-Like<br />
Symptoms: Successfully Treated by Sleeve Resection/R.<br />
Hurezeanu, A. Kaell, L. Cardinal, Port Jefferson, NY, p.A7748<br />
ATS 2016 • San Francisco