Final Program

MONDAY • MAY 16 225
717 Biomarkers of Endothelial and Epithelial Dysfunction in Adult
and Pediatric Acute Respiratory Distress Syndrome/N. Yehya,
T. Dolinay, N.J. Thomas, J.A. Howrylak, S.S. Margulies,
Philadelphia, PA, p.A4418
718 Oxylipin Profiling in the Acute Respiratory Distress
Syndrome/N. Larsson, S. Gouveia-Figueira, J. Claesson, S.
Lehtipalo, A.F. Behndig, J. Tyden, J. Johansson, R. Pinto, M.L.
Nording, Umea, Sweden, p.A4419
719 Inhibition of Phospholipase-Mediated Phoshatidylglycerol
Depletion and Replacement of Surfactant Improve Surfactant
Function in a Murine ARDS Model/R.D. Hite, A. Chakrabarti, M.V.
Novotny, M. Waite, M.C. Seeds, Cleveland, OH, p.A4420
720 Transpulmonary Pressure Based on Absolute Esophageal
Pressure Measurement Predicts Morphological Changes of
Lung Parenchyma in an Experimental Animal Model/J.
Fumagalli, C. Zhang, V. Torsani, M. Pirrone, S. Gomez, S.R.R. De
Santis, M.R. Tucci, O.P. Ramos, C. Lima, G. Bento, L. Berra, R.
Kacmarek, M.B.P. Amato, Boston, MA, p.A4421
721 Net Alveolar Fluid Clearance Is Associated with Phenotypes of
Lung Morphology in Acute Respiratory Distress Syndrome/R.
Blondonnet, J. Lutz, L. Roszyk, D. Bouvier, R. Guerin, S. Perbet, S.
Cayot, T. Godet, L. Blanchon, J.-E. Bazin, E. Futier, V. Sapin, J.-M.
Constantin, M. Jabaudon, Clermont-Ferrand, France, p.A4422
722 Lung Inflammation in ARDS and Heart Failure is Not Related to
the Degree of Regional Strain/K.A. Hibbert, T. Winkler, L.F. Cruz,
V.J. Kelly, C.A. Holland, K.L. Brait, J.G. Venegas, M. Vidal-Melo,
R.S. Harris, E.K. Bajwa, Boston, MA, p.A4423
723 Non-Invasive Assessment of Regional Respiratory Airflow in
Acute Respiratory Failure Patients/T. Mauri, C. Turrini, N. Eronia,
B. Cambiaghi, G. Grasselli, P. Tagliabue, T. Sasso, G. Bellani, L.
Gattinoni, A. Pesenti, Milan, Italy, p.A4424
724 Cell Therapy for the Treatment of Acute Lung Injury: Alveolar
type II Cells or Mesenchymal Stem Cells?/R. Guillamat-Prats, M.
Camprubi-Rimblas, F. Puig, R. Herrero, A. Serrano-Mollar, J. Tijero,
M.N. Gomez, L. Blanch, A. Artigas, Sabadell, Spain, p.A4425
725 The Composition of the Oral, Lung and Gut Microbiome in
Adult Critically Ill Patients with or at Risk for the Acute
Respiratory Distress Syndrome/G.D. Kitsios, A. Fitch, S.
Rapport, M.J. Morowitz, A.M. Morris, B.J. McVerry, Pittsburgh, PA,
p.A4426
B105
POSTER DISCUSSION SESSION
COPD: EPIDEMIOLOGY AND GENETICS
2:15 p.m. - 4:15 p.m. MOSCONE CENTER
Room 133 (North Building, Lower Level)
Poster Viewing 2:15-3:00
Discussion 3:00-4:15
Chairing: C.P. Hersh, MD, MPH, Boston, MA
I. Pavord, MD, Oxford, United Kingdom
M.C. McCormack, MD, MHS, Baltimore, MD
101 Identification of Novel Genes Related to Two Definitions of
Airway Obstruction in Never-Smokers/D.A. Van Der Plaat, K. De
Jong, A. Faiz, J.M. Vonk, C.C. Van Diemen, I. Nedeljkovic, N. Amin,
C.A. Brandsma, Y. Bosse, D.D. Sin, D.C. Nickle, C.M. Van Duijn,
D.S. Postma, H.M. Boezen, Groningen, Netherlands, p.A4427
102 Identification of Novel Genes Related to Obstruction of the
Small Airways in Adult Never-Smokers/D.A. Van Der Plaat, K.
De Jong, A. Faiz, J.M. Vonk, C.C. Van Diemen, I. Nedeljkovic, N.
Amin, C.A. Brandsma, Y. Bosse, D.D. Sin, D.C. Nickle, C.M. Van
Duijn, H.M. Boezen, D.S. Postma, Groningen, Netherlands,
p.A4428
103 Variants in the Nicotine Acetylcholine Receptor (CHRNA 3/5)
Locus May Play a Role in COPD Development Via Smoking
Status/D.A. Van Der Plaat, K. De Jong, J.M. Vonk, C.C. Van
Diemen, I. Nedeljkovic, N. Amin, C.M. Van Duijn, D.S. Postma,
H.M. Boezen, Groningen, Netherlands, p.A4429
104 Genome-Wide Association Analysis of Pulmonary Disease
Factors Reveals Different Genetic Variation for Emphysema
and Airway Disease/K.A. Young, G.L. Kinney, M.H. Cho, P.J.
Castaldi, T.H. Beaty, J.D. Crapo, E.K. Silverman, J. Hokanson,
S.M. Lutz, Aurora, CO, p.A4430
105 Genome-Wide Association Identifies rs28929474 (Glu342Lys)
in SERPINA1 Associated with Post-Bronchodilator FEV1/FVC
and Percent Predicted FEV1 in SPIROMICS/X. Li, V.E. Ortega,
E.J. Ampleford, R.G. Barr, D.J. Couper, M.K. Han, E.A. Hoffman,
R. Kanner, E. Kleerup, F.J. Martinez, P.G. Woodruff, G.A. Hawkins,
E.R. Bleecker, D.A. Meyers, Winston-Salem, NC, p.A4431
106 Association of CHRNA3 and CYP26A with Pulmonary Function
Is Partially Mediated by Smoking/S.M. Lutz, M.H. Cho, G.L.
Kinney, K.A. Young, T. Fingerlin, C. Lange, T.H. Beaty, E.K.
Silverman, J. Hokanson, Denver, CO, p.A4432
107 Rare SERPINA1 Variants in the Multi-Ethnic SPIROMICS
Population/V.E. Ortega, X. Li, W.K. O’Neal, E.J. Pennington, R.G.
Barr, D.J. Couper, M.K. Han, R. Kanner, E. Kleerup, F.J. Martinez,
S.P. Peters, MD, PhD, S.I. Rennard, P.G. Woodruff, E.A. Hoffman,
D.A. Meyers, E.R. Bleecker, Winston-Salem, NC, p.A4433
108 TLR4 Asp2999Gly (rs4986790) Is Associated with Chronic
Bronchitis and Decreased LPS-Induced IL-6 Production in
Agricultural Workers/L.A. Weissenburger-Moser, L. Smith, A.J.
Heires, K.M. Kelly, J.A. Merchant, J. Meza, D.J. Romberger, T.D.
LeVan, Omaha, NE, p.A4434
109 RGS6 Contribution to Chronic Obstructive Pulmonary Disease
and Lung Cancer/J. She, L. Zhu, C. Bai, P. Yang, Shanghai,
China, p.A4435
110 Epigenome-Wide Association Study in Blood DNA from a
Cohort of Chronic Obstructive Pulmonary Disease/W.J. Kim, J.
Park, H.-K. Koo, Chuncheon, Korea, Republic of, p.A4436
111 Genome-Wide Pathway Analysis of Chronic Bronchitis in the
Framingham Heart Study/S.-Y. Liao, D.C. Christiani, Riverside,
CA, p.A4437
112 Interaction of CD14 Haplotypes and Soluble CD14 on
Pulmonary Function in Agricultural Workers/T.D. LeVan, L.
Smith, A.J. Heires, J. Meza, L.A. Weissenburger-Moser, D.J.
Romberger, Omaha, NE, p.A4438
MONDAY AFTERNOON
ATS 2016 • San Francisco