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404 WEDNESDAY • MAY 18<br />

604 CARMA3 Mediates the Pulmonary Immune Response to<br />

Alternaria Alternata/B. Causton, K. Jones, J.L. Cho, B.D. Medoff,<br />

Charlestown, MA, p.A7545<br />

605 Novel Nasal Sampling Techniques Identify ILC2s as Important<br />

Responders in Asthma During Nasal Allergen Challenge/J.<br />

Dhariwal, A. Cameron, B. Trujillo-Torralbo, A. Del Rosario, M.<br />

Paulsen, D.J. Jackson, M.R. Edwards, D. Cousins, T.T. Hansel,<br />

S.L. Johnston, R.P. Walton, London, United Kingdom, p.A7546<br />

606 The Expression of the Interleukin-33 Receptor ST2L on<br />

Eosinophils Following Bronchial Allergen Challenge in Allergic<br />

Asthma Subjects/P.D. Mitchell, B. Watson, J.P. Oliveria, S. Smith,<br />

D. Tworek, A. El-Gammal, G. Gauvreau, R. Sehmi, P.M. O’Byrne,<br />

Hamilton, Canada, p.A7547<br />

607 IL-36 Induces Inflammation in the Lung/Y. Sun, H.A. Arnett,<br />

South San Francisco, CA, p.A7548<br />

608 Circadian Changes in Glucocorticoid Receptor Expression and<br />

Function in Airway Epithelial Cells/E.D. Larson, Z. Jiang, S. Ott,<br />

K. Chmiel, A.A. Zeki, A. Haczku, Davis, CA, p.A7549<br />

609 Dysregulation of Type 2 Innate Lymphoid Cells and TH2 Cells<br />

Impairs Diesel-Enhanced Allergic Airway Responses/S.<br />

Provoost, K.C. De Grove, R.W. Hendriks, L.J. Seys, S. Kumar, T.<br />

Maes, G.G. Brusselle, G.F. Joos, Ghent, Belgium, p.A7550<br />

610 TLR2 Contributes to Allergic Airway Inflammation Through<br />

JNK Signaling Pathway with Activation of Autophagy/L. Fang,<br />

R. Liu, Hefei, China, p.A7551<br />

611 Lung-Targeted Dual PI3Kgd Inhibition: Evidence for a Novel<br />

Therapeutic Strategy for Multiple Severe Asthma<br />

Phenotypes/M. Thomas, P. Bold, K. Bjorhall, A. Butcher, J.F.<br />

Carlsson, P. Cygan, M. Karlsson, H. Lindmark, M. Perry, M.<br />

Mogemark, V. Morrisson, M. Norberg, S. Rodrigo Blomqvist, C.<br />

Goodyear, K. Karabelas, Gothenburg, Sweden, p.A7552<br />

612 Peripheral Pathological ILC2: An Inflammatory Indicator for the<br />

Assessment of Asthma Control in Clinics/Z. Chen, Y. Jia, R.<br />

Tang, C. Bai, L. Zhu, Shanghai, China, p.A7553<br />

613 Role of ChemR23 Signaling in Diesel-Enhanced Allergic<br />

Airway Inflammation/K.C. De Grove, S. Provoost, G.L. Fraser,<br />

V.J. Lannoy, G.G. Brusselle, T. Maes, G.F. Joos, Ghent, Belgium,<br />

p.A7554<br />

614 CLEC-2 Regulates Type 2 and Type 17 Lung Inflammation/P.<br />

Burkett, A. Wallrapp, V.K. Kuchroo, Boston, MA, p.A7555<br />

615 Secreted Phospholipase A2 Group X Plays a Key Role in the<br />

Airway Response to an Inhaled Allergen and Orchestrates a<br />

Type-2 Innate Immune Response/J.D. Nolin, H.L. Ogden, Y. Lai,<br />

D. An, A.M. Manicone, C.W. Frevert, M.W. Gelb, W.A. Altemeier,<br />

T.S. Hallstrand, Seattle, WA, p.A7556<br />

616 Impact of High Sugar Diet on L-Arginine Metabolism in the<br />

Lung/A.L. Linderholm, M.R. Showalter, E.B. Nonnecke, B.L.<br />

Lonnerdal, O. Fiehn, N.J. Kenyon, Davis, CA, p.A7557<br />

617 Inhibition of RORa Blocks Rhinovirus-Induced Expansion of<br />

Type 2 Innate Lymphoid Cells and Expression of IL-13 in<br />

Immature Mice/C. Rajput, J.K. Bentley, T. Cui, J. Lei, M. Han, M.B.<br />

Hershenson, Ann Arbor, MI, p.A7558<br />

618 Elevated Levels of Circulating CRTh2+CD4+T Cells<br />

Characterize Severe Asthma/N. Shrestha Palikhe, C.R. Laratta,<br />

D. Nahirney, D. Vethanayagam, M. Bhutani, H. Vliagoftis, L.<br />

Cameron, Edmonton, Canada, p.A7559<br />

619 Peripheral Pathological Type 2 Innate Lymphoid Cells<br />

Associate with Human Asthma Control Status/Y. Jia, X. Fang,<br />

Z. Chen, R. Tang, Shanghai, China, p.A7560<br />

620 Alveolar Macrophages from Subjects with Asthma Release<br />

Pro-Inflammatory LTB4 in Ratio Excess to LXA4 Upon P2X7<br />

Stimulation, Promoting Fibrotic Remodeling/E.C. Roti Roti, E.E.<br />

Torr, P. Fichtinger, A. Guadarrama, N. Sandbo, L.C. Denlinger,<br />

Madison, WI, p.A7561<br />

621 Airway Epithelium-Specific Deletion of Leptin Receptor<br />

Worsens Murine Asthma/V. Anathy, B. Mihavics, N. Ubags, E.<br />

Dilli, A. Wallace, A.E. Dixon, B.T. Suratt, Burlington, VT, p.A7562<br />

622 Breastfeeding and Delivery Mode Modify the Association<br />

Between Maternal Atopy and Childhood Allergic<br />

Outcomes/N.S. Kasmikha, A. Sitarik, H. Kim, G. Wegienka, C.C.<br />

Johnson, S. Havstad, D. Ownby, E. Zoratti, Detroit, MI, p.A7563<br />

623 P2Y14 Receptor Activation Mediates LPS and Allergen Induced<br />

Pulmonary Leukocyte Recruitment in Mice/R.T. Amison, S.<br />

Arnold, B.G. O’Shaughnessey, S. Cicko, A. Meyer, M. Idzko, C.P.<br />

Page, S.C. Pitchford, London, United Kingdom, p.A7564<br />

624 Alternative Splicing of Exons 3 and 4 in IL-33 Is Associated<br />

with Type 2 Inflammation in Human Asthma/E. Gordon, A.<br />

Wesolowska-Andersen, C. Urbanek, M.E. Lachowicz-Scroggins, M.<br />

Peters, M. Seibold, J.V. Fahy, San Francisco, CA, p.A7565<br />

625 Helicobacter Pylori Elicits a Heightened Innate Immune<br />

Response in Pediatric Airway Epithelium : Evidence of NOD1<br />

Developmental Regulation/M.A. Dela Pena, M.T. Jimenez, J.V.<br />

Solnick, L.A. Miller, Davis, CA, p.A7566<br />

D102<br />

POSTER DISCUSSION SESSION<br />

FIGURING OUT WHAT WE DON’T KNOW:<br />

ADVANCES IN MEDICAL EDUCATION<br />

1:30 p.m. - 3:30 p.m. MOSCONE CENTER<br />

Room 304 (South Building, Esplanade Level)<br />

Poster Viewing 1:30-2:15<br />

Discussion 2:15-3:30<br />

Chairing: M.M. Hayes, MD, Boston, MA<br />

J.B. Richards, MD, MA, Charleston, SC<br />

R. Adamson, MBBS, Seattle, WA<br />

201 Building Research Capacity in Middle and Low-Income<br />

Countries Through Research Methodology and Career<br />

Development Education/C.M. Patino, D.H. Au, C.J. Lane, A.S.<br />

Buist, W.M. Vollmer, Los Angeles, CA, p.A7567<br />

202 Increased Mortality Associated with Resident Handoff in a<br />

Multi-Center Cohort/J.L. Denson, A. Jensen, H. Saag, B. Wang,<br />

Y. Fang, L. Horwitz, L. Evans, S. Sherman, Denver, CO, p.A7568<br />

ATS 2016 • San Francisco

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