Final Program
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404 WEDNESDAY • MAY 18<br />
604 CARMA3 Mediates the Pulmonary Immune Response to<br />
Alternaria Alternata/B. Causton, K. Jones, J.L. Cho, B.D. Medoff,<br />
Charlestown, MA, p.A7545<br />
605 Novel Nasal Sampling Techniques Identify ILC2s as Important<br />
Responders in Asthma During Nasal Allergen Challenge/J.<br />
Dhariwal, A. Cameron, B. Trujillo-Torralbo, A. Del Rosario, M.<br />
Paulsen, D.J. Jackson, M.R. Edwards, D. Cousins, T.T. Hansel,<br />
S.L. Johnston, R.P. Walton, London, United Kingdom, p.A7546<br />
606 The Expression of the Interleukin-33 Receptor ST2L on<br />
Eosinophils Following Bronchial Allergen Challenge in Allergic<br />
Asthma Subjects/P.D. Mitchell, B. Watson, J.P. Oliveria, S. Smith,<br />
D. Tworek, A. El-Gammal, G. Gauvreau, R. Sehmi, P.M. O’Byrne,<br />
Hamilton, Canada, p.A7547<br />
607 IL-36 Induces Inflammation in the Lung/Y. Sun, H.A. Arnett,<br />
South San Francisco, CA, p.A7548<br />
608 Circadian Changes in Glucocorticoid Receptor Expression and<br />
Function in Airway Epithelial Cells/E.D. Larson, Z. Jiang, S. Ott,<br />
K. Chmiel, A.A. Zeki, A. Haczku, Davis, CA, p.A7549<br />
609 Dysregulation of Type 2 Innate Lymphoid Cells and TH2 Cells<br />
Impairs Diesel-Enhanced Allergic Airway Responses/S.<br />
Provoost, K.C. De Grove, R.W. Hendriks, L.J. Seys, S. Kumar, T.<br />
Maes, G.G. Brusselle, G.F. Joos, Ghent, Belgium, p.A7550<br />
610 TLR2 Contributes to Allergic Airway Inflammation Through<br />
JNK Signaling Pathway with Activation of Autophagy/L. Fang,<br />
R. Liu, Hefei, China, p.A7551<br />
611 Lung-Targeted Dual PI3Kgd Inhibition: Evidence for a Novel<br />
Therapeutic Strategy for Multiple Severe Asthma<br />
Phenotypes/M. Thomas, P. Bold, K. Bjorhall, A. Butcher, J.F.<br />
Carlsson, P. Cygan, M. Karlsson, H. Lindmark, M. Perry, M.<br />
Mogemark, V. Morrisson, M. Norberg, S. Rodrigo Blomqvist, C.<br />
Goodyear, K. Karabelas, Gothenburg, Sweden, p.A7552<br />
612 Peripheral Pathological ILC2: An Inflammatory Indicator for the<br />
Assessment of Asthma Control in Clinics/Z. Chen, Y. Jia, R.<br />
Tang, C. Bai, L. Zhu, Shanghai, China, p.A7553<br />
613 Role of ChemR23 Signaling in Diesel-Enhanced Allergic<br />
Airway Inflammation/K.C. De Grove, S. Provoost, G.L. Fraser,<br />
V.J. Lannoy, G.G. Brusselle, T. Maes, G.F. Joos, Ghent, Belgium,<br />
p.A7554<br />
614 CLEC-2 Regulates Type 2 and Type 17 Lung Inflammation/P.<br />
Burkett, A. Wallrapp, V.K. Kuchroo, Boston, MA, p.A7555<br />
615 Secreted Phospholipase A2 Group X Plays a Key Role in the<br />
Airway Response to an Inhaled Allergen and Orchestrates a<br />
Type-2 Innate Immune Response/J.D. Nolin, H.L. Ogden, Y. Lai,<br />
D. An, A.M. Manicone, C.W. Frevert, M.W. Gelb, W.A. Altemeier,<br />
T.S. Hallstrand, Seattle, WA, p.A7556<br />
616 Impact of High Sugar Diet on L-Arginine Metabolism in the<br />
Lung/A.L. Linderholm, M.R. Showalter, E.B. Nonnecke, B.L.<br />
Lonnerdal, O. Fiehn, N.J. Kenyon, Davis, CA, p.A7557<br />
617 Inhibition of RORa Blocks Rhinovirus-Induced Expansion of<br />
Type 2 Innate Lymphoid Cells and Expression of IL-13 in<br />
Immature Mice/C. Rajput, J.K. Bentley, T. Cui, J. Lei, M. Han, M.B.<br />
Hershenson, Ann Arbor, MI, p.A7558<br />
618 Elevated Levels of Circulating CRTh2+CD4+T Cells<br />
Characterize Severe Asthma/N. Shrestha Palikhe, C.R. Laratta,<br />
D. Nahirney, D. Vethanayagam, M. Bhutani, H. Vliagoftis, L.<br />
Cameron, Edmonton, Canada, p.A7559<br />
619 Peripheral Pathological Type 2 Innate Lymphoid Cells<br />
Associate with Human Asthma Control Status/Y. Jia, X. Fang,<br />
Z. Chen, R. Tang, Shanghai, China, p.A7560<br />
620 Alveolar Macrophages from Subjects with Asthma Release<br />
Pro-Inflammatory LTB4 in Ratio Excess to LXA4 Upon P2X7<br />
Stimulation, Promoting Fibrotic Remodeling/E.C. Roti Roti, E.E.<br />
Torr, P. Fichtinger, A. Guadarrama, N. Sandbo, L.C. Denlinger,<br />
Madison, WI, p.A7561<br />
621 Airway Epithelium-Specific Deletion of Leptin Receptor<br />
Worsens Murine Asthma/V. Anathy, B. Mihavics, N. Ubags, E.<br />
Dilli, A. Wallace, A.E. Dixon, B.T. Suratt, Burlington, VT, p.A7562<br />
622 Breastfeeding and Delivery Mode Modify the Association<br />
Between Maternal Atopy and Childhood Allergic<br />
Outcomes/N.S. Kasmikha, A. Sitarik, H. Kim, G. Wegienka, C.C.<br />
Johnson, S. Havstad, D. Ownby, E. Zoratti, Detroit, MI, p.A7563<br />
623 P2Y14 Receptor Activation Mediates LPS and Allergen Induced<br />
Pulmonary Leukocyte Recruitment in Mice/R.T. Amison, S.<br />
Arnold, B.G. O’Shaughnessey, S. Cicko, A. Meyer, M. Idzko, C.P.<br />
Page, S.C. Pitchford, London, United Kingdom, p.A7564<br />
624 Alternative Splicing of Exons 3 and 4 in IL-33 Is Associated<br />
with Type 2 Inflammation in Human Asthma/E. Gordon, A.<br />
Wesolowska-Andersen, C. Urbanek, M.E. Lachowicz-Scroggins, M.<br />
Peters, M. Seibold, J.V. Fahy, San Francisco, CA, p.A7565<br />
625 Helicobacter Pylori Elicits a Heightened Innate Immune<br />
Response in Pediatric Airway Epithelium : Evidence of NOD1<br />
Developmental Regulation/M.A. Dela Pena, M.T. Jimenez, J.V.<br />
Solnick, L.A. Miller, Davis, CA, p.A7566<br />
D102<br />
POSTER DISCUSSION SESSION<br />
FIGURING OUT WHAT WE DON’T KNOW:<br />
ADVANCES IN MEDICAL EDUCATION<br />
1:30 p.m. - 3:30 p.m. MOSCONE CENTER<br />
Room 304 (South Building, Esplanade Level)<br />
Poster Viewing 1:30-2:15<br />
Discussion 2:15-3:30<br />
Chairing: M.M. Hayes, MD, Boston, MA<br />
J.B. Richards, MD, MA, Charleston, SC<br />
R. Adamson, MBBS, Seattle, WA<br />
201 Building Research Capacity in Middle and Low-Income<br />
Countries Through Research Methodology and Career<br />
Development Education/C.M. Patino, D.H. Au, C.J. Lane, A.S.<br />
Buist, W.M. Vollmer, Los Angeles, CA, p.A7567<br />
202 Increased Mortality Associated with Resident Handoff in a<br />
Multi-Center Cohort/J.L. Denson, A. Jensen, H. Saag, B. Wang,<br />
Y. Fang, L. Horwitz, L. Evans, S. Sherman, Denver, CO, p.A7568<br />
ATS 2016 • San Francisco