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108 SUNDAY • MAY 15<br />

12:15 Post-Prematurity Respiratory Disease<br />

R. Keller, MD, San Francisco, CA<br />

12:45 Assessing Severity of Post-Prematurity Respiratory Disease<br />

P.E. Moore, MD, Nashville, TN<br />

1:00 Infant Lung Function Outcomes at 1 Year in ELGANs<br />

S. Davis, MD, Indianapolis, IN<br />

L6<br />

NATIONAL HEART, LUNG, AND BLOOD INSTITUTE,<br />

DIVISION OF LUNG DISEASES, NIH<br />

MOLECULAR ATLAS OF LUNG DEVELOPMENT<br />

12:15 p.m. - 1:15 p.m. MOSCONE CENTER<br />

Room 2001/2003 (West Building, Level 2)<br />

Target Audience<br />

Providers of lung health, medical fellows in training, and basic researchers on<br />

lung biology, developmental biology, pediatrics, and informatics.<br />

Objectives<br />

At the conclusion of this session, the participant will be able to:<br />

• learn the newest datasets of LungMAP;<br />

• understand and learn the innovative technologies for molecular profiling and<br />

imaging of the developing lung;<br />

• learn how to access the LungMAP resources.<br />

Molecular Atlas of Lung Development (LungMAP) is an NHLBI-sponsored program.<br />

The overall goal of this program is to build an open-access reference resource by<br />

creating a comprehensive molecular atlas of the late-stage developing lung with data<br />

and reagents available to the research community. The atlas will integrate gene and<br />

protein expression profiles, transcriptome, epigenome, and other molecular<br />

characterizations with high-resolution anatomical information to provide molecular<br />

profiles of functionally or anatomically defined cell types in the developing lung.<br />

Participants in this session will learn about the newest data generated by the<br />

LungMAP, data analysis tools, and how to access the website, database and other<br />

publicly available resources of LungMAP.<br />

Chairing: R.F. Clark, PhD, Research Triangle Park, NC<br />

S. Lin, PhD, Bethesda, MD<br />

12:15 BREATH: A Web Accessible Database of Normal Human and<br />

Mouse Lung Development<br />

R.F. Clark, PhD, Research Triangle Park, NC<br />

12:27 Mass Spectrometry-Based Omics and High Throughput<br />

Imaging Characterization of Lung Development<br />

C. Ansong, PhD, Richland, WA<br />

12:39 Reconstructed Regulatory Networks Provide Novel Insights<br />

into Mechanisms of Postnatal Mouse Lung Development<br />

N. Ambalavanan, MD, Birmingham, AL<br />

12:51 LungMAP Postnatal Human Lung Tissue and Dissociated Cell<br />

Repository<br />

G.S. Pryhuber, MD, Rochester, NY<br />

L7<br />

NATIONAL HEART, LUNG, AND BLOOD INSTITUTE,<br />

DIVISION OF LUNG DISEASES, NIH<br />

NEW INSIGHTS ABOUT SEVERE ASTHMA FROM<br />

THE NHLBI SEVERE ASTHMA RESEARCH<br />

PROGRAM<br />

12:15 p.m. - 1:15 p.m. MOSCONE CENTER<br />

Room 2006/2008 (West Building, Level 2)<br />

Target Audience<br />

Providers of lung health, especially providers who manage patients with<br />

asthma; investigators interested in mechanisms of disease in asthma.<br />

Objectives<br />

At the conclusion of this session, the participant will be able to:<br />

• learn new findings about clinical and molecular phenotypes of severe asthma;<br />

• review research being supported by NHLBI to improve understanding of severe<br />

asthma and accelerate progress toward new treatments;<br />

• improve understanding of how the clinical features of severe asthma varies in<br />

children and adults.<br />

In this session on work in progress in the NHLBI-sponsored severe asthma research<br />

program, there are four presentations planned to provide the learner with a<br />

cutting-edge, data-driven understanding of the clinical features of pediatric and adult<br />

severe asthma. Each presentation will cover the context, rationale and recent<br />

progress in addressing clinically relevant questions in severe asthma pathobiology,<br />

diagnosis and management, including baseline cross-sectional data on recruited<br />

healthy and asthmatic subjects, their response to systemic corticosteroids, risk<br />

factors for asthma exacerbations as well as advances in imaging for the detection of<br />

pathologic mucus and its association with clinical outcome.<br />

Chairing: S.E. Wenzel, MD, Pittsburgh, PA<br />

T. Croxton, MD, PhD, Bethesda, MD<br />

12:15 Age and Gender Impacts<br />

W.G. Teague, MD, Charlottesville, VA<br />

12:30 Phenotypic Characteristics<br />

L.C. Denlinger, MD, PhD, Madison, WI<br />

12:45 Identification of Intraluminal Mucus by CT Imaging<br />

E. Dunican, MD, San Francisco, CA<br />

1:00 Characterization of Steroid Responsiveness<br />

E. Israel, MD, Boston, MA<br />

L8<br />

NATIONAL HEART, LUNG, AND BLOOD INSTITUTE,<br />

DIVISION OF LUNG DISEASES, NIH<br />

LESSONS LEARNED FROM THE NHLBI-SPONSORED<br />

TUBERCULOSIS SYSTEM BIOLOGY PROGRAM<br />

12:15 p.m. - 1:15 p.m. MOSCONE CENTER<br />

Room 2016/2018 (West Building, Level 2)<br />

Target Audience<br />

Providers of lung health, medical fellows in training, graduates, post-doctoral<br />

ATS 2016 • San Francisco

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